Theoretical Thermal Dosimetry In Realistic Patient Geometries For Regional Hyperthermia Treatment Of Cancer
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| Author | : Michel Gautherie |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 225 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642487122 |
When in the future improved and more flexible heating equipment becomes available, and when hyperthermia is applied more routinely, computerized simulations of treatments will become commonplace, as they are in radia tion therapy. For hyperthermia, however, such simulations will be used not only for the traditional role of planning patient treatment, but also for three other applications not needed in radiation therapy - the comparative evalu ation of equipment, feedback control during treatment, and the post-treat ment evaluation of therapy. The present simulations of hyperthermia are crude and simple when compared with what is required for these future ap plications, a fact which indicates the nedd for considerable research and de velopment in this area. Indeed, this research is proceeding rapidly within the hyperthermia community, whre three-dimensional power deposition and temperature calculations have just become available for realistic patief\t anatomies. Of equal significance are the even more rapid development in diagnostic imaging for the determination and display of patient anatomy and blood flow rates - information required for the planning of realistic hyperthermia treatment. These simulations will be very valuable tools which can be used to great ad vantage when combined with data obtained from treatments of patients.
| Author | : |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2018-07-31 |
| Genre | : Science |
| ISBN | : 9783319266947 |
This Handbook provides researchers, faculty, design engineers in industrial R&D, and practicing engineers in the field concise treatments of advanced and more-recently established topics in thermal science and engineering, with an important emphasis on micro- and nanosystems, not covered in earlier references on applied thermal science, heat transfer or relevant aspects of mechanical/chemical engineering. Major sections address new developments in heat transfer, transport phenomena, single- and multiphase flows with energy transfer, thermal-bioengineering, thermal radiation, combined mode heat transfer, coupled heat and mass transfer, and energy systems. Energy transport at the macro-scale and micro/nano-scales is also included. The internationally recognized team of authors adopt a consistent and systematic approach and writing style, including ample cross reference among topics, offering readers a user-friendly knowledgebase greater than the sum of its parts, perfect for frequent consultation. The Handbook of Thermal Science and Engineering is ideal for academic and professional readers in the traditional and emerging areas of mechanical engineering, chemical engineering, aerospace engineering, bioengineering, electronics fabrication, energy, and manufacturing concerned with the influence thermal phenomena.
| Author | : M.Heinrich Seegenschmiedt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 479 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642578586 |
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
| Author | : Leonore Handl-Zeller |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 195 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3709191556 |
This book presents all effective and safe techniques in interstitial hyperthermia and gives examples of applications in areas of clinical interest. Interstitial hyperthermia has been preferentially accepted by oncologists because it can be easily combined with other forms of treatment. One of the principal advantages is the threedimensionally restricted heat deposition to the tumor site. The contributions in this book are written by experts in the fields of biology, physics, and clinical implementation. The technical and clinical state of the art as well as quality assurance in interstitial hyperthermia is presented and practical information for the oncologists working in this field is given.
| Author | : Ping Xia, PhD |
| Publisher | : Springer Publishing Company |
| Total Pages | : 274 |
| Release | : 2015-09-08 |
| Genre | : Medical |
| ISBN | : 161705240X |
This guide & companion to the Radiation Oncology Self-Assessment Guide is a comprehensive physics review for anyone in the field of radiation oncology looking to enhance their knowledge of medical physics. It covers in depth the principles of radiation physics as applied to radiation therapy along with their technical and clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly ìflash cardî question and answer format with over 800 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The Guide is comprised of 14 chapters that lead the reader through the radiation oncology physics field, from basic physics to current practice and latest innovations. Aspects of basic physics covered include fundamentals, photon and particle interactions, and dose measurement. A section on current practice covers treatment planning, safety, regulations, quality assurance, and SBRT, SRS, TBI, IMRT, and IGRT techniques. A chapter unique to this volume is dedicated to those topics in diagnostic imaging most relevant to radiology, including MRI, ultrasound, fluoroscopy, mammography, PET, SPECT, and CT. New technologies such as VMAT, novel IGRT devices, proton therapy, and MRI-guided therapy are also incorporated. Focused and authoritative, this must-have review combines the expertise of clinical radiation oncology and radiation physics faculty from the Cleveland Clinic Taussig Cancer Institute. Key Features: Includes more than 800 questions with detailed answers and rationales A one-stop guide for those studying the physics of radiation oncology including those wishing to reinforce their current knowledge of medical physics Delivered in a ìflash cardî format to facilitate recall of key concepts and data Presents a unique chapter on diagnostic imaging topics most relevant to radiation oncology Content provided by a vast array of contributors, including physicists, radiation oncology residents, dosimetrists, and physicians About the Editors: Andrew Godley, PhD, is Staff Physicist, Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland OH Ping Xia, PhD, is Head of Medical Physics and Professor of Molecular Medicine, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
| Author | : Jennifer R. Bellon |
| Publisher | : Springer |
| Total Pages | : 162 |
| Release | : 2016-09-15 |
| Genre | : Medical |
| ISBN | : 3319403923 |
This book addresses the day-to-day treatment planning issues that radiation oncologists are likely to encounter during the treatment of breast cancer patients and provides numerous practical “tips” that will assist in navigation of the treatment planning process, from delineation of the tumor boundaries to discrimination of adjacent normal tissues and critical structures at risk of radiation injury. Differences in target delineation and treatment planning according to technique are emphasized, with coverage of conventional radiation therapy and advanced techniques including cardiac-sparing approaches, e.g., using active breathing control, intensity-modulated radiation therapy, proton beam therapy, and electron beam therapy post mastectomy. Individual chapters also focus on radiation setup and verification techniques and radiation treatment planning systems. The book, which is part of the Springer series Practical Guides in Radiation Oncology, is designed for hands-on use by radiation oncology residents/fellows in training and practicing radiation oncologists.
| Author | : Devashish Shrivastava |
| Publisher | : John Wiley & Sons |
| Total Pages | : 897 |
| Release | : 2018-07-02 |
| Genre | : Science |
| ISBN | : 1119127300 |
An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.
| Author | : Michael C. Joiner |
| Publisher | : CRC Press |
| Total Pages | : 711 |
| Release | : 2018-08-28 |
| Genre | : Medical |
| ISBN | : 0429955391 |
Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.
| Author | : Francis Duck |
| Publisher | : Academic Press |
| Total Pages | : 357 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483288420 |
This unique reference book describes quantitatively the measured and predicted values of all the physical properties of mammalian tissue. Reported measurements are thoroughly documented and are complemented by a range of empirical mathematical models which describe the observed physical behavior of tissue.**Intended as a broad-ranging reference, this volume gives the bioengineer, physicist, radiologist, or physiologist access to a literature which may not be known in detail. It will also be of value for those concerned with the study of a range of environmental radiation hazards.Most extensive compilation of values of physical properties of tissue**Presents data for thermal, optical, ultrasonic, mechanical, x-ray, electrical, and magnetic resonance properties**Comprehensive bibliography
| Author | : William M. Reichert |
| Publisher | : CRC Press |
| Total Pages | : 300 |
| Release | : 2007-12-17 |
| Genre | : Medical |
| ISBN | : 1420009303 |
Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
