Theoretical And Experimental Biophysics
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| Author | : Jay L. Nadeau |
| Publisher | : CRC Press |
| Total Pages | : 658 |
| Release | : 2016-04-19 |
| Genre | : Science |
| ISBN | : 1439897409 |
Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s
| Author | : Helmut Schiessel |
| Publisher | : CRC Press |
| Total Pages | : 420 |
| Release | : 2013-12-20 |
| Genre | : Science |
| ISBN | : 9814241652 |
Biophysics is a new way of looking at living matter. It uses quantitative experimental and theoretical methods to open a new window for studying and understanding life processes. This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.
| Author | : William Bialek |
| Publisher | : Princeton University Press |
| Total Pages | : 653 |
| Release | : 2012-12-17 |
| Genre | : Science |
| ISBN | : 1400845572 |
A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes
| Author | : Jay L. Nadeau |
| Publisher | : CRC Press |
| Total Pages | : 196 |
| Release | : 2015-03-25 |
| Genre | : Medical |
| ISBN | : 1466557664 |
Easily Get Started with Biological ExperimentsIntroduction to Experimental Biophysics - A Laboratory Guide presents wet lab methods for courses in biophysics or molecular biology. A companion to the author's highly praised An Introduction to Experimental Biophysics: Biological Methods for Physical Scientists, this manual offers a flexible course pl
| Author | : Fabio Trovato |
| Publisher | : Frontiers Media SA |
| Total Pages | : 322 |
| Release | : 2022-01-11 |
| Genre | : Science |
| ISBN | : 2889740250 |
| Author | : Rassier Dilson J.E |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 360 |
| Release | : 2010-09-08 |
| Genre | : Science |
| ISBN | : 1441963669 |
Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years. Early in the twentieth century, Fenn (1924, 1923) showed that the total energy liberated during a contraction (heat + work) was increased when the muscle was allowed to shorten and perform work. The result implied that chemical reactions during contractions were load-dependent. The observation underlying the “Fenn effect” was taken to a greater extent when Hill (1938) published a pivotal study showing in details the relation between heat production and the amount of muscle shortening, providing investigators with the force-velocity relation for skeletal muscles. Subsequently, two papers paved the way for the current paradigm in the field of muscle contraction. Huxley and Niedergerke (1954), and Huxley and Hanson (1954) showed that the width of the A-bands did not change during muscle stretch or activation. Contraction, previously believed to be caused by shortening of muscle filaments, was associated with sliding of the thick and thin filaments. These studies were followed by the classic paper by Huxley (1957), in which he conceptualized for the first time the cross-bridge theory; filament sliding was driven by the cyclical interactions of myosin heads (cross-bridges) with actin. The original cross-bridge theory has been revised over the years but the basic features have remained mostly intact. It now influences studies performed with molecular motors responsible for tasks as diverse as muscle contraction, cell division and vesicle transport.
| Author | : Gigi Foster |
| Publisher | : Academic Press |
| Total Pages | : 362 |
| Release | : 2019-02-08 |
| Genre | : Business & Economics |
| ISBN | : 0128130938 |
Biophysical Measurement in Experimental Social Science Research is an ideal primer for the experimental social scientist wishing to update their knowledge and skillset in the area of laboratory-based biophysical measurement. Many behavioral laboratories across the globe have acquired increasingly sophisticated biophysical measurement equipment, sometimes for particular research projects or for financial or institutional reasons. Yet the expertise required to use this technology and integrate the measures it can generate on human subjects into successful social science research endeavors is often scarce and concentrated amongst a small minority of researchers. This book aims to open the door to wider and more productive use of biophysical measurement in laboratory-based experimental social science research. Suitable for doctoral students through to established researchers, the volume presents examples of the successful integration of biophysical measures into analyses of human behavior, discussions of the academic and practical limitations of laboratory-based biophysical measurement, and hands-on guidance about how different biophysical measurement devices are used. A foreword and concluding chapters comprehensively synthesize and compare biophysical measurement options, address academic, ethical and practical matters, and address the broader historical and scientific context. Research chapters demonstrate the academic potential of biophysical measurement ranging fully across galvanic skin response, heart rate monitoring, eye tracking and direct neurological measurements. An extended Appendix showcases specific examples of device adoption in experimental social science lab settings. - Demonstrates the strengths and limitations of different tools, in terms of both research objectives and practicality - Provides hands-on guidance for device usage and data integration and assessment - Compares and contrasts the use of different biophysical data options for different research objectives and in different disciplines
| Author | : Alexander Vologodskii |
| Publisher | : Cambridge University Press |
| Total Pages | : 279 |
| Release | : 2015-03-12 |
| Genre | : Science |
| ISBN | : 1107034930 |
This book surveys the last sixty years of research in the rapidly advancing field of DNA biophysics, addressing key questions and facilitating further research.
| Author | : Joel Mispelter |
| Publisher | : World Scientific Publishing Company |
| Total Pages | : 754 |
| Release | : 2015-05-27 |
| Genre | : Technology & Engineering |
| ISBN | : 1783268042 |
NMR Probeheads for Biophysical and Biomedical Experiments 2nd Edition is essential reading for anyone in the field of NMR or MRI, from students to medical or biological scientists performing experiments under certain physical and/or geometrical conditions, unattainable by conventional or available probes. The material guides the reader through the most basic and comprehensive stages in accomplishing a correct probe design, from a very basic oscillating circuit to much more elaborate designs.This new edition has been revised and updated to include a chapter dedicated to RF components, which are commonly used for probes realization and their frequency-dependent characteristics. Another completely revised chapter concerns the multiple coil systems and discusses arrays coils, different decoupling methods, and some principles for interfacing coils with low-noise preamplifiers. The principles of linear circuit analysis are presented in a dedicated chapter. Last but not least, accompanying files containing updated software for probe design have been made available from the publisher's website.
| Author | : Fritz-Albert Popp |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 499 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 9401703736 |
Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.
