The book presents the proceedings of the XXV National Congress of the Italian Association of Theoretical and Applied Mechanics (Palermo, September 2022). The topics cover theoretical, computational, experimental and technical-applicative aspects. Chapters: Fluid Mechanics, Solid Mechanics, Structural Mechanics, Mechanics of Machine, Computational Mechanics, Biomechanics, Masonry Modelling and Analysis, Dynamical Systems in Civil and Mechanical Structures, Control and Experimental Dynamics, Mechanical Modelling of Metamaterials and Periodic Structures, Novel Stochastic Dynamics, Signal Processing Techniques for Civil Engineering Applications, Vibration-based Monitoring and Dynamic Identification of Historic Constructions, Modeling and Analysis of Nanocomposites and Small-Scale Structures, Gradient Flows in Mechanics and Continuum Physics, Multibody Systems Vibration Analysis, Mechanics of Renewable Energy Systems, Mathematical Modeling and Experimental Techniques for Quantification and Prediction of Fluid Dynamic Noise, and Advanced Process Mechanics. Keywords: Fluid Mechanics, Solid Mechanics, Structural Mechanics, Mechanics of Machine, Computational Mechanics, Biomechanics, Masonry Modelling and Analysis, Dynamical Systems in Civil and Mechanical Structures, Control and Experimental Dynamics, Mechanical Modelling of Metamaterials and Periodic Structures, Novel Stochastic Dynamics, Signal Processing Techniques for Civil Engineering Applications, Vibration-based Monitoring and Dynamic Identification of Historic Constructions, Modeling and Analysis of Nanocomposites and Small-Scale Structures, Gradient Flows in Mechanics and Continuum Physics, Multibody Systems Vibration Analysis, Mechanics of Renewable Energy Systems, Mathematical Modeling and Experimental Techniques for Quantification and Prediction of Fluid Dynamic Noise, and Advanced Process Mechanics.