The Zebrafish: Disease Models and Chemical Screens
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 748 |
| Release | : 2017-01-25 |
| Genre | : Science |
| ISBN | : 0128034874 |
The Zebrafish: Disease Models and Chemical Screens
The Zebrafish Disease Models And Chemical Screens
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The Zebrafish: Disease Models and Chemical Screens
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 591 |
| Release | : 2011-09-09 |
| Genre | : Technology & Engineering |
| ISBN | : 0123813212 |
This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens
The Zebrafish: Disease Models and Chemical Screens
| Author | : H. William Detrich |
| Publisher | : Academic Press |
| Total Pages | : 591 |
| Release | : 2011-09-23 |
| Genre | : Medical |
| ISBN | : 0123813204 |
This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens
The Zebrafish: Disease Models and Chemical Screens
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 616 |
| Release | : 2011-10-07 |
| Genre | : Technology & Engineering |
| ISBN | : 9780123813206 |
This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens
Zebrafish
| Author | : Patricia McGrath |
| Publisher | : John Wiley & Sons |
| Total Pages | : 360 |
| Release | : 2012-01-03 |
| Genre | : Science |
| ISBN | : 1118102142 |
Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using zebrafish as a tool for toxicology studies. Consolidating key protocols and approaches to help researchers navigate the important and evolving field of zebrafish models for toxicity screening, this new title describes the methods for using the zebrafish as a model organism to assess compound-induced toxicity on all major organs. Individual chapters that concentrate on assays for each organ system are included and various analytical tools including microscopy, microplate readers, high content imaging systems, ECG, blood pressure monitors, high speed video and motion detectors are described.
Zebrafish in Development and Disease
| Author | : Gokhan Dalgin |
| Publisher | : Frontiers Media SA |
| Total Pages | : 157 |
| Release | : 2019-12-06 |
| Genre | : |
| ISBN | : 2889632482 |
There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.
Zebrafish: A Model for Marine Peptide Based Drug Screening
| Author | : Saravanan Ramachandran |
| Publisher | : Springer |
| Total Pages | : 73 |
| Release | : 2019-06-14 |
| Genre | : Medical |
| ISBN | : 9811378444 |
This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
Cancer and Zebrafish
| Author | : David M. Langenau |
| Publisher | : Springer |
| Total Pages | : 552 |
| Release | : 2016-05-10 |
| Genre | : Medical |
| ISBN | : 3319306545 |
This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
