Antimicrobials

Antimicrobials
Author: Flavia Marinelli
Publisher: Springer Science & Business Media
Total Pages: 363
Release: 2013-10-04
Genre: Medical
ISBN: 3642399681

Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.

Crime and the Imaginary of Disaster

Crime and the Imaginary of Disaster
Author: M. Yar
Publisher: Springer
Total Pages: 185
Release: 2015-05-05
Genre: Social Science
ISBN: 1137509074

This study explores the 'imaginary of disaster' that appears in popular fictions about the apocalyptic breakdown of society. Focusing on representations of crime, law, violence, vengeance and justice, it argues that an exploration post-apocalyptic story-telling offer us valuable insights into social anxieties.

The Philosophy of the Western

The Philosophy of the Western
Author: Jennifer L. McMahon
Publisher: University Press of Kentucky
Total Pages: 379
Release: 2010-05-28
Genre: Political Science
ISBN: 081312591X

The great German novelist Thomas Mann implored readers to resist the persistent and growing militarism of the mid-twentieth century. To whom should we turn for guidance during this current era of global violence, political corruption, economic inequality, and environmental degradation? For more than two millennia, the worldÕs great thinkers have held that the ethically Ògood lifeÓ is the highest purpose of human existence. Renowned political philosopher Fred Dallmayr traces the development of this notion, finding surprising connections among Aristotelian ethics, Abrahamic and Eastern religious traditions, German idealism, and postindustrial social criticism. In Search of the Good Life does not offer a blueprint but rather invites readers on a cross-cultural quest. Along the way, the author discusses the teachings of Aristotle, Confucius, Nicolaus of Cusa, Leibniz, and Schiller, in addition invoking more recent writings of Gadamer and Ricoeur, as guideposts and sources of hope during our troubled times. Among contemporary themes Dallmayr discusses are the role of the classics in education, proper and improper ways of spreading democracy globally, the possibility of transnational citizenship, the problem of politicized evil, and the role of religion in our predominantly secular culture. Dallmayr restores the notion of the good life as a hallmark of personal conduct, civic virtue, and political engagement, and as the road map to enduring peace. In Search of the Good Life seeks to arouse complacent and dispirited citizens, guiding them out of the distractions of shallow amusements and perilous resentments in the direction of mutual learning and civic pedagogyÑa direction that will enable them to impose accountability on political leaders who stray from fundamental ethical standards.

Sketches of Virginia

Sketches of Virginia
Author: William Henry Foote
Publisher: Legare Street Press
Total Pages: 0
Release: 2023-07-18
Genre:
ISBN: 9781019657836

Originally published in the mid-19th century, this book provides a richly detailed history of Virginia from colonial times up through the antebellum period. Written by a prominent Virginia clergyman and historian, this book is an essential resource for anyone interested in the history of the Old Dominion. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Patterson's American Education

Patterson's American Education
Author: Homer L. Patterson
Publisher:
Total Pages: 712
Release: 1904
Genre: Education
ISBN:

The most current information on United States secondary schools-- both public and private-- in a quick, easy-to-use format.

The Imago Sequence

The Imago Sequence
Author: Laird Barron
Publisher: Start Publishing LLC
Total Pages: 429
Release: 2007-07-01
Genre: Fiction
ISBN: 1597802581

The title story of this collection — a devilishly ironic riff on H. P. Lovecraft’s “Pickman’s model” — was nominated for a World Fantasy Award, while “Probiscus” was nominated for an International Horror Guild award and reprinted in The Year’s Best Fantasy and Horror 19. In addition to his previously published work, this collection contains an original story.