The Togaviridae And Flaviviridae
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| Author | : Sondra Schlesinger |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 464 |
| Release | : 2013-03-09 |
| Genre | : Medical |
| ISBN | : 1475707851 |
The publication of this volume of The Viruses entitled The Togaviridae and Flaviviridae comes at an appropriate time. The structure and rep lication strategies of these viruses are now known to be sufficiently di verse to warrant the removal of flaviviruses from the Togaviridae family and establish them as an independent family. Flaviviridae have a special place in the history of virology. The prototype virus-yellow fever virus was the first virus to be identified as the cause of a human disease. Some of the history of this discovery is described in Chapter 1 of this volume; in Chapter 10 the complete sequence of the RNA genome of the virus is presented. This sequence not only defines the primary structure of the viral proteins, it also clarifies the mechanism of translation of the fla vivirus genome. Knowledge of the sequence of the structural proteins of these viruses represents an important step in the potential goal of using purified flavivirus glycoproteins as vaccines. Many of the chapters in this volume focus on the structure and replication of the Togaviridae. These viruses have provided valuable models for studies in cell biology, partic ularly with regard to the cotranslational and posttranslational steps re quired for the synthesis and localization of membrane glycoproteins. Fur thermore, Togaviridae have been pivotal in our growing understanding of how enveloped viruses enter and exit from cells. The broad outlines of the structure and gene expression of Togavir idae and Flaviviridae are known, but important questions remain.
| Author | : Nikos Vasilakis |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2016 |
| Genre | : Medical |
| ISBN | : 9781910190210 |
Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research literature. In addition authors identify the most pressing questions that remain to be answered, thus providing a stimulus for future research. Topics include: taxonomy, genome organization, virus-host and virus-vector interactions, evolutionary history, role of vertical transmission in arbovirus maintenance and evolution, epidemiology, arbovirus replication, pathogenesis, arbovirus diagnostics and control, including vaccines, novel anti-viral drugs, RNA interference and genetically modified vectors. Essential reading for every arbovirologist and highly recommended for all virologists and public health officials. [Subject: Microbiology, Life Science, Arbovirology, Virology, Taxonomy, Epidemiology]
| Author | : International Committee on Taxonomy of Viruses |
| Publisher | : Elsevier |
| Total Pages | : 1463 |
| Release | : 2011-10-25 |
| Genre | : Science |
| ISBN | : 0123846846 |
The practical need to partition the world of viruses into distinguishable, universally agreed upon entities is the ultimate justification for developing a virus classification system. Since 1971, the International Committee on Taxonomy of Viruses (ICTV) operating on behalf of the world community of virologists has taken on the task of developing a single, universal taxonomic scheme for all viruses infecting animals (vertebrate, invertebrates, and protozoa), plants (higher plants and algae), fungi, bacteria, and archaea. The current report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005. Representing the work of more than 500 virologists worldwide, this report is the authoritative reference for virus organization, distinction, and structure.
| Author | : Walter R Schlesinge |
| Publisher | : Elsevier |
| Total Pages | : 704 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0323138268 |
The Togaviruses: Biology, Structure, Replication deals with the biology, structure, and replication of rotaviruses. This book covers topics such as the biochemistry of rotaviruses and the biological and medical challenges they pose. It also gives an account of their mechanisms of replication that might lead to perceptions of the capacity to solve biological and epidemiological problems through the concepts and technology of molecular biology. This text is comprised of 21 chapters that explore clinical details, routine procedures for diagnostic virus isolation and identification and for serological tests; immunological host responses; the role of interferons; antiviral chemotherapy; and vaccine development. The discussion begins with a historical overview of arboviruses, followed by a description of all the viruses that belong to Togaviridae. These include alpha- and flaviviruses, rubiviruses, pestiviruses, and other ""non-arbo"" togaviruses. The next chapters focus on the arthropod-vertebrate-arthropod transmission cycle and its experimental equivalents, along with the viruses' structure, composition, and replication. This book concludes with a summary of physicochemical, morphological, and clinical data on non-arbo togaviruses. This reference material will be of interest to physicians, veterinarians, ecologists, entomologists, epidemiologists, cell biologists, immunologists, virologists, physical chemists, biochemists, molecular biologists, and geneticists.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 607 |
| Release | : 2003-12-18 |
| Genre | : Medical |
| ISBN | : 0080493831 |
Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. - Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions - Descibes the technologies that have contributed to our current knowledge about the Flaviviruses - Identifies the major problems faced in understanding the virus-host interactins that result in disease - An exhaustive compendium of current and past knowledge on the Flavivirus family
| Author | : Susan Payne |
| Publisher | : Elsevier |
| Total Pages | : 439 |
| Release | : 2022-09-23 |
| Genre | : Science |
| ISBN | : 0323984762 |
Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses. The book includes major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions, and methods to study. In addition, the book assesses the connections between the aforementioned topics and provides an integrated approach and in-depth understanding of how viruses work. The new edition also provides an expanded methods chapter containing new information on deep sequencing for in virus identification, mathematical formulas to calculate titers and a description of quantitiative PCR for enumerating viruses. The vaccine chapter has been updated to include vaccine efficacy, mRNA vaccines and SARS-CoV-2 vaccine development. The viral pathogenesis chapter has been expanded to include mechanisms of virally induced cancers. Viral taxonomy sections have been updated and chapters revised to accommodate new virus family designations. New chapters include nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and COVID-19/SARS-CoV-2. - Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies, and host responses - Presents a review of host cell, molecular biology, and the immune system - Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts - Includes text boxes throughout with experimental approaches used by virologists - Covers learning objectives in each chapter
| Author | : Carlos Brisola Marcondes |
| Publisher | : Springer |
| Total Pages | : 642 |
| Release | : 2016-11-09 |
| Genre | : Medical |
| ISBN | : 3319138847 |
Arthropod borne diseases cause enormous morbidity and mortality in most countries, mostly in those situated in tropical areas, but also in temperate regions. This book provides organized information on all arthropod related diseases, to prevent suffering and deaths, for medical students and professionals. Since arthropod borne diseases are present in many regions of the world and can even surprise professionals and lays in non-endemic regions, like malaria in UK and Canada, the author and its many expert collaborators are sure that it will be essential in all hospitals, clinics and medical libraries around the world. As arthropod borne diseases of domesticated animals are very numerous and in some cases related to human diseases, they are also included in the book.
| Author | : Peter M. Howley |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 2737 |
| Release | : 2020-02-11 |
| Genre | : Medical |
| ISBN | : 1975112555 |
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.
| Author | : Christopher J. Burrell |
| Publisher | : Academic Press |
| Total Pages | : 605 |
| Release | : 2016-11-09 |
| Genre | : Science |
| ISBN | : 0123751578 |
Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control
| Author | : Hans-Wolfgang Ackermann |
| Publisher | : CRC Press |
| Total Pages | : 261 |
| Release | : 2000-11-29 |
| Genre | : Medical |
| ISBN | : 1420039113 |
Viral Pathogenesis in Diagrams is the first book of its kind to illustrate viral pathogenesis on a comparative basis. The text covers the pathogenesis of viral diseases, including vertebrates, invertebrates, plants, and protists. The diagrams summarize and integrate large numbers of observations, from electron microscopy to clinical data, into a si
