The Therapeutics Of The Respiratory Passages
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Severe Asthma
Author | : Kian Fan Chung |
Publisher | : European Respiratory Society |
Total Pages | : 365 |
Release | : 2019-06-01 |
Genre | : Medical |
ISBN | : 1849841047 |
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Regulation of Tissue Oxygenation, Second Edition
Author | : Roland N. Pittman |
Publisher | : Biota Publishing |
Total Pages | : 117 |
Release | : 2016-08-18 |
Genre | : Medical |
ISBN | : 1615047212 |
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
How Tobacco Smoke Causes Disease
Author | : United States. Public Health Service. Office of the Surgeon General |
Publisher | : |
Total Pages | : 728 |
Release | : 2010 |
Genre | : Government publications |
ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Anatomy and Physiology
Author | : J. Gordon Betts |
Publisher | : |
Total Pages | : 0 |
Release | : 2013-04-25 |
Genre | : |
ISBN | : 9781947172807 |
Disorders of the Respiratory Tract
Author | : Matthew L. Mintz |
Publisher | : Springer Science & Business Media |
Total Pages | : 335 |
Release | : 2007-11-10 |
Genre | : Medical |
ISBN | : 1597450413 |
A concise review of the epidemiology, pathogenesis, and management of common respiratory conditions seen in a primary care setting. Using an illuminating case-based approach, Dr. Mintz assesses the key clinical questions that a primary care physician would ask and applies the most up-to-date research and guidelines to offer the practitioner evidence-based solutions. The author covers the range of knowledge needed to provide excellent care for patients with respiratory disease, from the basics of pulmonary function testing to understanding and caring for common respiratory illnesses, including chronic obstructive pulmonary disease, asthma, allergic rhinitis, and pneumonia. For each disorder, Dr. Mintz explains the key points regarding the epidemiology of the disease, its pathophysiology, the differential diagnosis and diagnosis, and its recommended treatment. A special PDA version of Disorders of the Respiratory Tract: Common Challenges in Primary Care is also available.
Encyclopedia of Respiratory Medicine
Author | : Geoffrey J. Laurent |
Publisher | : Academic Press |
Total Pages | : 680 |
Release | : 2006 |
Genre | : Medical |
ISBN | : |
An impressive four-volume work that provides an authoritative and comprehensive coverage of the complete field of respiratory medicine. It provides a vital interface between the pure and clinical science environments covering all aspects of respiratory medicine from the relevant molecular biology to the treatment of diseases that affect the respiratory system. It includes comprehensive coverage of lung cells, the structural components of the lung and key molecules that regulate lung function as well as all the major respiratory diseases. Students, researchers and professionals alike will find this an authoritative source of information on all aspects of respiratory medicine. Also available online via ScienceDirect (2006) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. Includes diagrams of uniformly high quality and references to enable readers to access the wider literature Highly structured through the use of chapter templates Key four-color illustrations that will be invaluable teaching tools
ERS Handbook of Respiratory Medicine
Author | : Paolo Palange |
Publisher | : European Respiratory Society |
Total Pages | : 891 |
Release | : 2019-09-01 |
Genre | : Medical |
ISBN | : 1849840806 |
The European Respiratory Society (ERS) Handbook of Respiratory Medicine, now in its third edition, is a concise, compact and easy-to-read guide to each of the key areas in respiratory medicine. Its 20 sections, written by clinicians and researchers at the forefront of the field, explain the structure and function of the respiratory system, its disorders and how to treat them. The Handbook is a must-have for anyone who intends to remain up to date in the field, and to have within arm's reach a reference that covers everything from the basics to the latest developments in respiratory medicine.
Disease Control Priorities, Third Edition (Volume 5)
Author | : Dorairaj Prabhakaran |
Publisher | : World Bank Publications |
Total Pages | : 948 |
Release | : 2017-11-17 |
Genre | : Medical |
ISBN | : 1464805202 |
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
Respiratory Care Anatomy and Physiology
Author | : Will Beachey, PhD, RRT, FAARC |
Publisher | : Elsevier Health Sciences |
Total Pages | : 483 |
Release | : 2012-10-22 |
Genre | : Medical |
ISBN | : 0323078664 |
Perfect for both practicing therapists and students in respiratory therapy and associated professions, this well-organized text offers the most clinically relevant and up-to-date information on respiratory applied anatomy and physiology. Content spans the areas of basic anatomy and physiology of the pulmonary, cardiovascular, and renal systems, and details the physiological principles underlying common therapeutic, diagnostic, and monitoring therapies and procedures. Using a clear and easy-to-understand format, this text helps you take a more clinical perspective and learn to think more critically about the subject matter. Open-ended concept questions require reasoned responses based on thorough comprehension of the text, fostering critical thinking and discussion. Clinical Focus boxes throughout the text place key subject matter in a clinical context to connect theory with practice. Chapter outlines, chapter objectives, key terms, and a bulleted chapter summary highlight important concepts and make content more accessible. Appendixes contain helpful tables and definitions of terms and symbols. NEW! Chapter on the physiological basis for treating sleep-disordered breathing clarifies the physiological mechanisms of sleep-disordered breathing and the various techniques required to treat this type of disorder. NEW! Reorganization of content places the section on the renal system before the section on integrated responses in exercise and aging to create a more logical flow of content. NEW! More Clinical Focus scenarios and concept questions provide additional opportunities to build upon content previously learned and to apply new information in the text.