The Tablet of Water

The Tablet of Water
Author: D. Dean Harmon
Publisher: Lulu.com
Total Pages: 323
Release: 2009-03-30
Genre: Fiction
ISBN: 0557058686

Brian Sihdlham's infant son is sick and no one in his village can help, so he starts on a trek to seek out the help of the most powerful sound shaper he knows of: The Great Sage. Little did Brian know that finding the old man was the easy part. The wizened shaper tells him that to help his son, Brian needs to read and follow the instructions on the Tablets of Wefas. Dark followers collide with Brian as he seeks to find them, setting in motion a series of events that have been foretold by prophets and prophecy for thousands of years. The Tablet of Water follows Brian as he starts his journey to learn about himself, his family, the magic of sound, and what it means to follow the principles spelled out upon the Tablets.

Formulating Poorly Water Soluble Drugs

Formulating Poorly Water Soluble Drugs
Author: Robert O. Williams III
Publisher: Springer
Total Pages: 781
Release: 2016-12-16
Genre: Medical
ISBN: 3319426095

The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop

Water-Insoluble Drug Formulation

Water-Insoluble Drug Formulation
Author: Ron Liu
Publisher: CRC Press
Total Pages: 736
Release: 2018-03-12
Genre: Medical
ISBN: 1498729428

Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field. The aim of this book is to provide a handy reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. In addition, this book may be useful to pharmacy and chemistry undergraduate students and pharmaceutical and biopharmaceutical graduate students to enhance their knowledge in the techniques of drug solubilization and dissolution enhancement.

Drug Delivery Strategies for Poorly Water-Soluble Drugs

Drug Delivery Strategies for Poorly Water-Soluble Drugs
Author: Dionysios Douroumis
Publisher: John Wiley & Sons
Total Pages: 543
Release: 2012-12-19
Genre: Science
ISBN: 1118444671

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.

Laboratory Manual of Community Pharmacy and Management

Laboratory Manual of Community Pharmacy and Management
Author: Dr. Remeth J. Dias
Publisher: Trinity Publishing House, Satara
Total Pages: 196
Release: 2023-09-28
Genre: Medical
ISBN: 8195520014

We are very pleased to put forth the revised edition of 'Laboratory Manual of Community Pharmacy and Management'. We have incorporated all the suggestions, modified it to make it easier, student friendly and relevant in terms of achieving curriculum outcome. We are very much thankful to all the learned teachers who have given their feedback whole-heartedly. We have even incorporated the changes in this manual based on the feedback given by the teachers from all the institutes. Now, we believe that the manual has been fulfilling the aspirations of pharmacology teachers and students too. This manual is prepared as per PCI Education Regulations, 2020 for Diploma Course in Pharmacy. The manual is designed to train the students for improving their professional skills of providing various pharmaceutical care services in community pharmacy. The special emphasis is given on the activities that can be performed in the community pharmacy so that the students can do the effective patient counselling on various chronic diseases. The practical manual helps students to gain in-depth knowledge of providing professional services like handling of prescriptions, preparation of dispensing and auxiliary labels, health screening services, administration techniques of various dosage forms and use of community pharmacy software for the betterment of the community health. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. Moreover, assessment scheme is also given to help the student and teacher to know what is to be assessed. Every experiment has the component of activity or role play included so that the students will be able to interact with the patients and give them the counselling tips on administration, proper use and storage of the dosage forms. The preparation of counselling materials such as patient information leaflets is also included as an activity. We acknowledge the help and cooperation extended by various persons in bringing out this manual. We are highly indebted to the authors of various books and articles mentioned in references of each experiment, which became a major source of information for writing this manual. We also admire the publishers, designers, and printers who graciously worked hard to publish this manual. Hope this manual will help the students to learn the concept, principles and perform the activities and role play for counselling the public about diseases and medications. We wish you all the best!!!

Sounds

Sounds
Author:
Publisher: Ginn
Total Pages: 28
Release: 2001-03-22
Genre: Materials
ISBN: 0602299659

Designed to provide the ideal solution for teaching junior science, "New Star Science 6" books are aimed at the sixth primary school year. These teacher's notes provide a background to the unit as well as photocopiables and assessment material. The focus of this text is "different changes".

Pharmaceutical Dosage Forms - Tablets

Pharmaceutical Dosage Forms - Tablets
Author: Larry L. Augsburger
Publisher: CRC Press
Total Pages: 1558
Release: 2016-04-19
Genre: Medical
ISBN: 1420063863

The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients. Pharmaceutical Dosage Forms: Tablets, Third Edition is a comprehensive resource of the design, formulation, manufacture, and evaluation of the tablet dosage form, an

The Complete Book on Water Soluble Polymers

The Complete Book on Water Soluble Polymers
Author: NPCS Board of Consultants & Engineers
Publisher: ASIA PACIFIC BUSINESS PRESS Inc.
Total Pages: 628
Release: 2009-10-01
Genre:
ISBN: 8178331233

Water soluble polymers cover a wide range of highly varied families of products of natural or synthetic origin, and have numerous uses. A water soluble polymer is a polymer that can be diluted in water, with or without the assistance of co solvents and neutralizing agents, to form transparent solutions. They may be classified into two types, totally synthetic polymers and natural products together with their chemically modified derivatives and further can be grouped into three main headings; naturally occurring, semi synthetic and completely synthetic polymers. The water based polymers are quick drying non inflammable, having mild odour and more environmentally acceptability than any other polymers. Most conventional coating polymers at present can be produced in a form that will allow them to be solubilized in water. These include alkydes, polyesters, acrylics epoxies. There are various types of polymerization methods of water soluble polymers such as bulk polymerization, solution polymerization, copolymerization, emulsion polymerization and suspension polymerization. Water soluble polymers are used widely as stabilizers or protective colloids in emulsion polymerization. Its most common use are gum acacia, starch either etherified or in its degraded form, dextrin, polyvinyl alchohol and hydroxyethyl cellulose. Polymers find many applications in oil recovery and production, including areas such as; drilling fluids, cementation of well bore, reservoir fracturing, controlling fluid flow in the reservoir and multistage processes of oil production and refining. The water soluble polymers market encompasses several categories, including starch, cellulose ethers, polyvinylacetate, polyvinyl alcohol and other synthetic water soluble polymers. The starch market is the largest. This book basically deals with flow characteristics of water soluble polymer solutions, emulsion polymerization, water reducible resins, silicone modified alkyds and polyesters, cross linking of water soluble coatings, formulation of water soluble coatings, trouble shooting with water soluble polymers, acrylic solution resins, polyvinylpyrrolidone, commercial uses: compounding and formulating adhesives, methods of polymerization, methods for polymerization of acrylamide, fabrication of water soluble polymers, excluded volume interactions of neutral polymers etc. The book covers classification of water soluble polymers, processes, properties, uses and applications of water soluble polymers with lot of other information. This book will be very resourceful for new entrepreneurs, existing units, technocrats, researchers and technical libraries. TAGS Acrylic, Applications of polymer emulsions, Best small and cottage scale industries, Book on Water Soluble Polymers, Business guidance for Water Soluble Polymers, Business Plan for a Startup Business, Business start-up, Cellulose, Coatings based on waterborne dispersions, Compounding of water soluble polymers, Derivatives, Fabrication of water soluble polymers, Great Opportunity for Startup, How to start a successful Water Soluble Polymers business, How to Start a Water Soluble Polymers Business, How to Start a Water Soluble Polymers?, How to Start Water Soluble Polymers Industry in India, Industrial Water Soluble Polymers, Maleinized, Modern small and cottage scale industries, Most Profitable Water Soluble Polymers Business Ideas, New small scale ideas in Water Soluble Polymers industry, Poly (etylene oxide), Polyesters, Polymer small molecule interactions, Polymerization of water soluble polymers, Polymers Based Small Scale Industries Projects, Polymers in oil recovery and production, Polymers, Polyvinyl alcohol, Polyvinylpyrrolidone, Profitable small and cottage scale industries, Profitable Small Scale Water Soluble Polymers, Project for startups, Properties of water soluble polymers, Requirements for biodegradable water soluble polymers, Rheology, Setting up and opening your Water Soluble Polymers Business, Setting up of Water Soluble Polymers Units, Silicone, Small scale Commercial Water Soluble Polymers, Small scale Water Soluble Polymers production line, Small Scale Water Soluble Polymers Projects, Small Start-up Business Project, Start Up India, Stand Up India, Starting a Water Soluble Polymers Business, Start-up Business Plan for Water Soluble Polymers, Startup ideas, Startup Project, Startup Project for Water Soluble Polymers, Startup project plan, Synthetic, Thermodynamics of non-ionic water soluble polymers, Thixotropy, Water solubility and sensivity, Water soluble polymer in emulsion, Water soluble polymers as stabilizers, Water Soluble Polymers Based Profitable Projects, Water Soluble Polymers Business, Water Soluble Polymers Compounding, Water Soluble Polymers for Industrial Applications, Water Soluble Polymers for Industrial Water Treatment, Water Soluble Polymers for Pharmaceutical Applications, Water Soluble Polymers Formulation, Water Soluble Polymers Industry in India, Water Soluble Polymers Manufacturing, Water Soluble Polymers Projects, Water Soluble Polymers Solution Properties and Applications, Water Soluble Polymers Specialty Chemicals, Water Soluble Polymers, Water-reducible resins, Water-Soluble Polymers, Synthetic Chemical, What products are made from water soluble polymers?

Medicine for the Outdoors E-Book

Medicine for the Outdoors E-Book
Author: Paul S. Auerbach
Publisher: Elsevier Health Sciences
Total Pages: 562
Release: 2015-01-30
Genre: Medical
ISBN: 0323340970

Since 1986, Medicine for the Outdoors has been hailed as the definitive take-along manual on the subject. Packed with step-by-step instructions and how-to explanations, this updated edition tells you the best way to respond to just about any medical problem. Logically organized, simple-to-understand enhanced illustrations and an increased focus on new topics mean this medical reference book may literally save your life. Whether you're venturing into mountains, deserts, forests, or out to sea, it belongs in your pack! - Examine the most diverse and comprehensive coverage of medical conditions related to the outdoors. - Be guided through logical and complete explanations of every topic. - Enhance your understanding with descriptive material including numerous drawings and instructions. - Research recommendations for injury and illness prevention. - Locate answers quickly with a helpful comprehensive index. - Clearly visualize how to perform specific treatments, such as the use of a SAM® splint, with an increased number of helpful illustrations. - Stay abreast of the latest in emergency medicine care, including new antibiotics, medicines, products to control bleeding, and today's most common infectious disease threats. - Enhance your understanding of Lyme disease; water disinfection; emerging diseases (including West Nile Virus); and how to seek safety and act during natural disasters. - Take advantage of Dr. Auerbach's expert guidance with revised recommendations on high-altitude problems, drowning, airways management, toxic plants, and snake bites. - Access new appendices covering AIDS/HIV transmission, expanded treatment instructions, global conflict guidelines (including terrorism), and canine medicine. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Wilderness Medicine E-Book

Wilderness Medicine E-Book
Author: Paul S. Auerbach
Publisher: Elsevier Health Sciences
Total Pages: 2931
Release: 2011-10-31
Genre: Medical
ISBN: 1455733563

Quickly and decisively manage any medical emergency you encounter in the great outdoors with Wilderness Medicine! World-renowned authority and author, Dr. Paul Auerbach, and a team of experts offer proven, practical, visual guidance for effectively diagnosing and treating the full range of emergencies and health problems encountered in situations where time and resources are scarce. Every day, more and more people are venturing into the wilderness and extreme environments, or are victims of horrific natural disasters...and many are unprepared for the dangers and aftermath that come with these episodes. Whether these victims are stranded on mountaintops, lost in the desert, injured on a remote bike path, or ill far out at sea, this indispensable resource--now with online access at www.expertconsult.com for greater accessibility and portability-- equips rescuers and health care professionals to effectively address and prevent injury and illness in the wilderness! This textbook is widely referred to as "The Bible of Wilderness Medicine." Be able to practice emergency medicine outside of the traditional hospital/clinical setting whether you are in remote environments, underdeveloped but highly populated areas, or disaster areas, are part of search and rescue operations, or dealing with casualties from episodes of extreme sports and active lifestyle activities. Face any medical challenge in the wilderness with expert guidance: Dr. Auerbach is a noted author and the world's leading authority on wilderness medicine. He is a founder and Past President of the Wilderness Medical Society, consultant to the Divers Alert Network and many other agencies and organizations, and a member of the National Medical Committee for the National Ski Patrol System. Handle everything from frostbite to infection by marine microbes, not to mention other diverse injuries, bites, stings, poisonous plant exposures, animal attacks, and natural disasters. Grasp the essential aspects of search and rescue. Respond quickly and effectively by improvising with available materials. Improve your competency and readiness with the latest guidance on volcanic eruptions, extreme sports, splints and slings, wilderness cardiology, living off the land, aerospace medicine, mental health in the wilderness, tactical combat casualty care, and much more. Meet the needs and special considerations of specific patient populations such as children, women, elders, persons with chronic medical conditions, and the disabled. Make smart decisions about gear, navigation, nutrition, and survival. Be prepared for everything with expanded coverage on topics such as high altitude, cold water immersion, and poisonous and venomous plants and animals. Get the skills you need now with new information on global humanitarian relief and expedition medicine, plus expanded coverage of injury prevention and environmental preservation. Get guidance on the go with fully searchable online text, plus bonus images, tables and video clips - all available on ExpertConsult.com.