The Psychopharmacology of Hallucinogens

The Psychopharmacology of Hallucinogens
Author: Richard C. Stillman
Publisher: Elsevier
Total Pages: 349
Release: 2013-10-22
Genre: Medical
ISBN: 1483146065

The Psychopharmacology of Hallucinogens focuses on the properties, compositions, functions, transformations, and reactions of hallucinogens. The selection first offers information on the biosynthesis and action of hallucinogens in mammals; role of biogenic amines in the actions of monomethoxy-amphetamines; and molecular mechanism of action of hallucinogens. The book then takes a look at the molecular determinants for interaction with the LSD receptor, including biological studies, molecular reactivity, and summation of the molecular polarization complexes. The text examines the progress on the development of a receptor model for hallucinogenic amphetamines; characterization of psychotomimetics; physical identification of hallucinogenic compounds; and aspects of the pharmacology of phencyclidine. The book also underscores the effects of LSD, mescaline, and DMT, including effects on humans, proposed model, and effects of monoamine manipulations. The text also presents analysis of hallucinogens by Pavlovian conditioning, behavioral measures of hallucinogenic behavior, and drug model of hallucinosis. The selection is a dependable reference for readers interested in the study of hallucinogens.

Behavioral Neurobiology of Psychedelic Drugs

Behavioral Neurobiology of Psychedelic Drugs
Author: Adam L. Halberstadt
Publisher: Springer
Total Pages: 434
Release: 2018-03-27
Genre: Medical
ISBN: 3662558807

This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action. Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.

Neuropsychedelia

Neuropsychedelia
Author: Nicolas Langlitz
Publisher: Univ of California Press
Total Pages: 334
Release: 2013
Genre: Medical
ISBN: 0520274822

Neuropsychedelia examines the revival of psychedelic science since the "Decade of the Brain." After the breakdown of this previously prospering area of psychopharmacology, and in the wake of clashes between counterculture and establishment in the late 1960s, a new generation of hallucinogen researchers used the hype around the neurosciences in the 1990s to bring psychedelics back into the mainstream of science and society. This book is based on anthropological fieldwork and philosophical reflections on life and work in two laboratories that have played key roles in this development: a human lab in Switzerland and an animal lab in California. It sheds light on the central transnational axis of the resurgence connecting American psychedelic culture with the home country of LSD. In the borderland of science and religion, Neuropsychedelia explores the tensions between the use of hallucinogens to model psychoses and to evoke spiritual experiences in laboratory settings. Its protagonists, including the anthropologist himself, struggle to find a place for the mystical under conditions of late-modern materialism.

Psychedelic Psychiatry

Psychedelic Psychiatry
Author: Erika Dyck
Publisher: JHU Press
Total Pages: 217
Release: 2008-09-15
Genre: Medical
ISBN: 1421400758

LSD's short but colorful history in North America carries with it the distinct cachet of counterculture and government experimentation. The truth about this mind-altering chemical cocktail is far more complex—and less controversial—than generally believed. Psychedelic Psychiatry is the tale of medical researchers working to understand LSD’s therapeutic properties just as escalating anxieties about drug abuse in modern society laid the groundwork for the end of experimentation at the edge of psychopharmacology. Historian Erika Dyck deftly recasts our understanding of LSD to show it as an experimental substance, a medical treatment, and a tool for exploring psychotic perspectives—as well as a recreational drug. She recounts the inside story of the early days of LSD research in small-town, prairie Canada, when Humphry Osmond and Abram Hoffer claimed incredible advances in treating alcoholism, understanding schizophrenia and other psychoses, and achieving empathy with their patients. In relating the drug’s short, strange trip, Dyck explains how concerns about countercultural trends led to the criminalization of LSD and other so-called psychedelic drugs—concordantly opening the way for an explosion in legal prescription pharmaceuticals—and points to the recent re-emergence of sanctioned psychotropic research among psychiatric practitioners. This challenge to the prevailing wisdom behind drug regulation and addiction therapy provides a historical corrective to our perception of LSD’s medical efficacy.

Clinical Manual of Addiction Psychopharmacology

Clinical Manual of Addiction Psychopharmacology
Author: Henry R. Kranzler
Publisher: American Psychiatric Pub
Total Pages: 466
Release: 2014-10-03
Genre: Medical
ISBN: 1585625280

Clinical Manual of Addiction Psychopharmacology is a comprehensive guide to the pharmacology of drugs of abuse and the medications used to treat dependence on those substances. This new, second edition provides a thorough update on a broad range of addictive substances, along with enhanced coverage in areas where significant advances have been made since publication of the first edition. Clinicians, including psychiatrists, psychiatric residents and fellows, and other mental health practitioners who encounter individuals with substance-related disorders in the course of their clinical work, will find the manual to be well-organized, exhaustively referenced, and current. The book is structured for ease of use and completeness of coverage, with an abundance of beneficial features: Material is presented in a systematic fashion, addressing epidemiology, pharmacology of the abused substance (including pharmacokinetics and pharmacodynamics), psychopharmacological treatments, and issues of dependence, tolerance, withdrawal, and abstinence. Both basic science and clinical dimensions are addressed, and these different perspectives, including pharmacotherapy and the psychosocial aspects of treatment, are integrated to allow clinicians a more holistic and effective treatment approach. Coverage of the pharmacology of drugs of abuse is thorough and reflects the latest research findings, providing a necessary background for understanding the clinical effects and treatment of dependence on these substances. Coverage of pharmacotherapy for dependence on these drugs is equally comprehensive, with meticulously detailed findings and evidence-based recommendations for the clinical care of patients dependent on a variety of substances. Tables are used strategically to present complex information in a logical and accessible way; for example, the table on management of alcohol withdrawal syndrome includes detailed information on the symptom-triggered approach, fixed dose schedules, and delirium in a condensed, yet easy-to-understand format. The book is well written and edited for clarity and accuracy by editors and contributors at the forefront of the psychopharmacology of addiction. As new drugs come into the market and old drugs find new applications, clinicians must stay current to provide the best care. Clinical Manual of Addiction Psychopharmacology helps them to do just that, offering both sound science and clinical wisdom to meet the complex challenges of treating individuals with substance-related disorders.

Turn On, Tune In, Drop Out

Turn On, Tune In, Drop Out
Author: Timothy Leary
Publisher: Ronin Publishing
Total Pages: 121
Release: 2009-04-01
Genre: Body, Mind & Spirit
ISBN: 1579511058

Written in the psychedelic era, Turn On, Tune In, Drop Out is Timothy Leary at his best, beckoning with humor and irreverence, a vision of individual empowerment, personal responsibility, and spiritual awakening. Includes: Start Your Own Religion Education as an Addictive Process Soul Session Buddha as Drop-Out Mad Virgin of Psychedelia God's Secret Agent o Homage to Huxley The Awe-Ful See-Er o The Molecular Revolution MIT is TIM Backwards Neurological Politics "Trickster is a major figure in American Indian folk Wisdom. Also in Sufi Tales … a certain type of "rascal"-with a grin and a wink (and wisdom beyond wisdom) … in the Zen tradition this is known as the School of Crazy Wisdom … Timothy Leary-in his own inimitable way-has become the twentieth century's grand master of crazy wisdom …" - Dr. Jeffrey Mishlove

The Psychopharmacology of Herbal Medicine

The Psychopharmacology of Herbal Medicine
Author: Marcello Spinella
Publisher: MIT Press
Total Pages: 596
Release: 2001-06-08
Genre: Medical
ISBN: 0262307162

A compilation of current scientific knowledge about psychoactive herbal drugs. Virtually all cultures consume drugs from psychoactive plants. Caffeine, for example, is probably the most common stimulant in the world, and many modern medicines, such as morphine and codeine, are derived from plant sources. In these cases, scientific research has revealed the composition of the plants and how they interact with the nervous system. There are also many herbal medications with reputed therapeutic value that have not yet gained acceptance into mainstream medicine, partly because there has not been enough research to support their usefulness. Instead they are regarded as "alternative medicines." This is an active research area, however, and many current studies are focusing on identifying the active components, pharmacological properties, physiological effects, and clinical efficacy of herbal medicines. This book compiles and integrates the most up-to-date information on the major psychoactive herbal medicines—that is, herbal medicines that alter mind, brain, and behavior. It focuses particularly on the effects on various areas of cognition, including attention, learning, and memory. The book covers all major classes of psychoactive drugs, including stimulants, cognitive enhancers, sedatives and anxiolytics, psychotherapeutic herbs, analgesics and anesthetic plants, hallucinogens, and cannabis.

Toxicology Cases for the Clinical and Forensic Laboratory

Toxicology Cases for the Clinical and Forensic Laboratory
Author: Hema Ketha
Publisher: Academic Press
Total Pages: 542
Release: 2020-06-20
Genre: Medical
ISBN: 0128163739

Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. - Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format - Presents unique and challenging cases in clinical laboratories contributed by experts in the field - Consolidated format that make concepts in toxicology easy to learn and teach - Key learning points highlighted with multiple choice questions

Fifty Years of LSD: Current Status and Perspectives of Hallucinogens

Fifty Years of LSD: Current Status and Perspectives of Hallucinogens
Author: D. Ladewig
Publisher: CRC Press
Total Pages: 250
Release: 1994-08-15
Genre: Medical
ISBN: 9781850705697

This volume is the proceedings of the Symposium of the Swiss Academy of Medical Sciences held in Lugano-Agno in Switzerland in September 1993. It includes chapters in pharmacological, psychopathological and clinical aspects of LSD and hallucinogenic drug use in medicine, in addition to a personal historical account of the discovery of LSD by Professor Albert Hofmann, as well as social and cultural aspects of LSD.