The Metabolic Ghetto

The Metabolic Ghetto
Author: Jonathan C. K. Wells
Publisher: Cambridge University Press
Total Pages: 625
Release: 2016-07-21
Genre: Science
ISBN: 1316679365

Chronic diseases have rapidly become the leading global cause of morbidity and mortality, yet there is poor understanding of this transition, or why particular social and ethnic groups are especially susceptible. In this book, Wells adopts a multidisciplinary approach to human nutrition, emphasising how power relations shape the physiological pathways to obesity, diabetes, hypertension and cardiovascular disease. Part I reviews the physiological basis of chronic diseases, presenting a 'capacity-load' model that integrates the nutritional contributions of developmental experience and adult lifestyle. Part II presents an evolutionary perspective on the sensitivity of human metabolism to ecological stresses, highlighting how social hierarchy impacts metabolism on an intergenerational timescale. Part III reviews how nutrition has changed over time, as societies evolved and coalesced towards a single global economic system. Part IV integrates these physiological, evolutionary and politico-economic perspectives in a unifying framework, to deepen our understanding of the societal basis of metabolic ill-health.

The Metabolic Ghetto

The Metabolic Ghetto
Author: Jonathan C. K. Wells
Publisher: Cambridge University Press
Total Pages: 625
Release: 2016-07-21
Genre: Business & Economics
ISBN: 1107009472

A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.

Eat Like the Animals

Eat Like the Animals
Author: David Raubenheimer
Publisher: Harvest
Total Pages: 261
Release: 2020
Genre: Health & Fitness
ISBN: 1328587851

Our evolutionary ancestors once possessed the ability to intuit what food their bodies needed, in what proportions, and ate the right things in the proper amounts--effortlessly balanced. When and why did we lose this ability, and how can we get it back? David Raubenheimer and Stephen Simpson answer these questions in a compelling narrative, based upon five "eureka" moments they experienced in the course of their groundbreaking research. The book shares their colorful scientific journey--from the foothills of Cape Town, to the deserts of Australia--culminating in a unifying theory of nutrition that has profound implications for our current epidemic of metabolic diseases and obesity. The authors ultimately offer useful prescriptions to understand the unwanted side effects of fad diets, gain control over one's food environment, and see that delicious and healthy are integral parts of proper eating.

Developmental Origins of Health and Disease

Developmental Origins of Health and Disease
Author: Peter Gluckman
Publisher: Cambridge University Press
Total Pages: 542
Release: 2006-04-20
Genre: Medical
ISBN: 9780521847438

This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.

Sexing the Body

Sexing the Body
Author: Anne Fausto-Sterling
Publisher: Basic Books
Total Pages: 621
Release: 2020-06-30
Genre: Social Science
ISBN: 1541672909

Now updated with groundbreaking research, this award-winning classic examines the construction of sexual identity in biology, society, and history. Why do some people prefer heterosexual love while others fancy the same sex? Is sexual identity biologically determined or a product of convention? In this brilliant and provocative book, the acclaimed author of Myths of Gender argues that even the most fundamental knowledge about sex is shaped by the culture in which scientific knowledge is produced. Drawing on astonishing real-life cases and a probing analysis of centuries of scientific research, Fausto-Sterling demonstrates how scientists have historically politicized the body. In lively and impassioned prose, she breaks down three key dualisms -- sex/gender, nature/nurture, and real/constructed -- and asserts that individuals born as mixtures of male and female exist as one of five natural human variants and, as such, should not be forced to compromise their differences to fit a flawed societal definition of normality.

The Evolutionary Biology of Human Body Fatness

The Evolutionary Biology of Human Body Fatness
Author: Jonathan C. K. Wells
Publisher: Cambridge University Press
Total Pages: 395
Release: 2010
Genre: Health & Fitness
ISBN: 0521884209

Integrates medical and evolutionary data on the role of body fat in human biology, including the current obesity epidemic.

The Rise of Fetal and Neonatal Physiology

The Rise of Fetal and Neonatal Physiology
Author: Lawrence D. Longo
Publisher: Springer
Total Pages: 879
Release: 2018-02-01
Genre: Medical
ISBN: 1493974831

This second edition offers an expanded and updated history of the field of fetal and neonatal development, allowing readers to gain a comprehensive understanding of the biological aspects that contribute to the wellbeing or pathophysiology of newborns. In this concluding opus of a long and prominent career as a clinical scientist, Dr. Longo has invited new contributions from noted colleagues with expertise in various fields to provide a historical perspective on the impact of how modern concepts emerged in the field of fetal physiology and contributed to the current attention paid to the fetal origins of diseases in adults. In addition to new chapters on maternal physiology and complications during pregnancy, others trace the history of the Society for Reproductive Investigation, governmental funding of perinatal research, and major initiatives to support training in the new discipline of maternal fetal medicine, including the Reproductive Scientist Development program. The extensive survey provided by the author, who personally knew most of the pioneers in the field, offers a unique guide for all clinical and basic scientists interested in the history of – and future approaches to diagnosing and treating – pathologies that represent the leading causes of neonatal mortality and, far too often, life-long morbidity.

Impressionable Biologies

Impressionable Biologies
Author: Maurizio Meloni
Publisher: Routledge
Total Pages: 279
Release: 2019-01-10
Genre: Social Science
ISBN: 135168938X

During the twentieth century, genes were considered the controlling force of life processes, and the transfer of DNA the definitive explanation for biological heredity. Such views shaped the politics of human heredity: in the eugenic era, controlling heredity meant intervening in the distribution of "good" and "bad" genes. However, since the turn of the twenty-first century, this centrality of genes has been challenged by a number of "postgenomic" disciplines. The rise of epigenetics in particular signals a shift from notions of biological fixedness to ideas of plasticity and "impressionability" of biological material. This book investigates a long history of the beliefs about the plasticity of human biology, starting with ancient medicine, and analyses the biopolitical techniques required to govern such permeability. It looks at the emergence of the modern body of biomedicine as a necessary displacement or possibly reconfiguration of earlier plastic views. Finally, it analyses the returning of plasticity to contemporary postgenomic views and argues that postgenomic plasticity is neither a modernistic plasticity of instrumental management of the body nor a postmodernist celebration of potentialities. It is instead a plasticity that disrupts clear boundaries between openness and determination, individual and community, with important implications for notions of risk, responsibility and intervention.

Uncivilised Genes

Uncivilised Genes
Author: Gustav Milne
Publisher: Crown House Publishing Ltd
Total Pages: 295
Release: 2017-08-31
Genre: Medical
ISBN: 1781352836

In Uncivilised Genes: Human Evolution and the Urban Paradox, Gustav Milne explores how we can reconfigure our lifestyles and urban environments, based on an understanding of our prehistoric past, in order to bring about a richer future for mankind. We evolved as hunter-gatherers over a period of more than three million years: living off the land within small tribal societies in a symbiotic working relationship with nature. Understanding this legacy and how our evolution has determined our social, psychological, nutritional and physiological needs means we can adopt what Milne has termed evolutionary-concordant behaviours: behaviours designed to reconcile the fundamental mismatch between our current urban lifestyles and our ancient biology. Our ancestral diets and lifestyles could hold the secret not only to enhancing our health and happiness but also to combating the prevalence of western lifestyle diseases such as obesity, type 2 diabetes and various types of cancer to name but a few. Milne expertly evaluates these challenges - along with many other issues pertinent to our urban wellbeing - and proposes solutions within our reach, including adaptations to our dietary regimes, lifestyle-embedded activities and school and university curriculums, and a re-engineering of our built environment to better suit our needs. Drawing on what archaeological evidence reveals about Palaeolithic and Mesolithic diets, as well as on anthropological studies of contemporary hunter-gatherer societies, Uncivilised Genes offers timely insights to enhance our collective and individual health and prosperity. It also shines a spotlight on the evolutionary determinants of social behaviour, and looks at how we can bridge the gap between the world we are creating and the un-urbanised, uncivilised world to which we are genetically and psychologically better adapted. This book is not a rejection of modernity. Neither is it a call to reject towns and seek solace in a rural idyll, nor another celebrity-endorsed fad diet or exercise programme. Rather, it is a comprehensive chronicle of the myriad factors that continue to contribute to our societal and personal wellbeing, and a broad-ranging blueprint for a richer future more in tune with our basic physiology, psychology, metabolism and mindset. Essential reading for anyone interested in living a healthier, more evolutionary-concordant life. Contents include: 1. In the Beginning; 2. Genesis; 3. A View of the Garden; 4. A Hunger Game; 5. Food for Thought; 6. Body of Evidence; 7. A Life Less Sedentary; 8. Lost Tribes; 9. Hunter-Gatherer vs. Football-Shopper; 10. Music and Words; 11. Green and Pleasant; 12. Central Park; 13. Old Town; 14. Urban Regeneration; 15. Revelations.

The Routledge Handbook of Paleopathology

The Routledge Handbook of Paleopathology
Author: Anne L. Grauer
Publisher: Taylor & Francis
Total Pages: 693
Release: 2022-12-30
Genre: Health & Fitness
ISBN: 1000820424

This book 1. explores current methods and techniques employed by paleopathologists as means to highlight the range of data that can be generated. 2. introduces a range of diseases and conditions that have been noted in the fossil, archaeological, and historical record, offering readers a foundational understanding of pathological conditions, along with their potential etiologies. 3. will be indispensable for archaeologists, bioarchaeologists and historians, and those in medical fields, as it reflects current scholarship within paleopathology and the field’s impact on our understanding of health and disease in the past, the present, and implications for our future.