Marek's Disease

Marek's Disease
Author: Fred Davison
Publisher: Academic Press
Total Pages: 208
Release: 2004-09-30
Genre: Medical
ISBN: 9780120883790

Marek's disease is a form of cancer of poultry caused by an important herpesvirus (MDV). It continues to be a threat to poultry health and welfare and worldwide losses are estimated to be US$ 1 billion annually. Marek's Disease provides a timely review of the problems of Marek's disease with descriptions of the complex viral life cycle, how MDV targets different types of white blood cells, and details of the virus structure, its genes and proteins. The multiplicity of factors contributing to susceptibility is explored in detail Vaccination - the problems arising from current vaccination strategies and how these can be improved and made sustainable in future The lessons learned in the control of MD over the past 30 years, and how we can use MD as a model for other animal and human diseases is discussed

Marek’s Disease

Marek’s Disease
Author: K. Hirai
Publisher: Springer Science & Business Media
Total Pages: 302
Release: 2012-12-06
Genre: Medical
ISBN: 3642568637

Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses. This volume gives an overview on many aspects of MDV research and summarizes recent advances in the field. The topics include the history, biology,and molecular biology of MDV, pathogenesis, vaccinal immunity, immune response, genetic resistance and development of recombinant polyvalent vaccines. It is hoped that this volume will make an important contribution towards the control of infectious diseases.

Human Herpesviruses

Human Herpesviruses
Author: Ann Arvin
Publisher: Cambridge University Press
Total Pages: 1325
Release: 2007-08-16
Genre: Medical
ISBN: 1139461648

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Avian Immunology

Avian Immunology
Author: Bernd Kaspers
Publisher: Academic Press
Total Pages: 456
Release: 2012-12-02
Genre: Medical
ISBN: 0123972728

The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research

Varicella-zoster Virus

Varicella-zoster Virus
Author: Allison Abendroth
Publisher: Springer Science & Business Media
Total Pages: 382
Release: 2010-09-30
Genre: Medical
ISBN: 3642127282

This book offers a comprehensive review of basic and clinical research on Varicella-zoster Virus, the only human herpesvirus for which vaccines to prevent both primary and recurrent infection are approved.

Diseases of Poultry

Diseases of Poultry
Author: Aly M. Fadly
Publisher: John Wiley & Sons
Total Pages: 2938
Release: 2011-11-16
Genre: Medical
ISBN: 1119949505

Now in its Twelfth Edition, Diseases of Poultry continues its tradition of excellence as the definitive reference of poultry disease. Following the same user-friendly format, the book has been thoroughly updated to reflect the most current knowledge of avian pathology, including new coverage of genetic resistance to disease. Coverage is given to both common and uncommon diseases, and chapters are organized by disease type, including viral, bacterial, fungal, parasitic diseases as well as others, such as nutritional, developmental, metabolic, noninfectious diseases and toxins. Each disease section provides detailed coverage of history, etiology, pathobiology, diagnosis, and intervention strategies, as well as the economic and public health significance of each disease. With a host of international authors, Diseases of Poultry is a must-have resource for all veterinary pathologists, practitioners, agricultural managers and industry leaders involved in poultry health and production.