Insect infestations can severely damage museum collections and buildings. This Technical Bulletin is intended as a guide to help museum staff understand commercial pest control operations. It describes chemical methods of controlling insects, and includes information on regulations, modes of action, and application methods necessary for the safe use of insecticides. Insecticide safety and poisoning are also discussed, and the properties and side-effects of specific insecticides are outlined. Pest-by-pest recommendations guide the reader in deciding upon the appropriate chemical method of control.