Genetic Twists of Fate

Genetic Twists of Fate
Author: Stanley Fields
Publisher: MIT Press
Total Pages: 235
Release: 2010-09-24
Genre: Science
ISBN: 0262289008

How tiny variations in our personal DNA can determine how we look, how we behave, how we get sick, and how we get well. News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

The Oxford Handbook of Quantitative Methods, Vol. 2: Statistical Analysis

The Oxford Handbook of Quantitative Methods, Vol. 2: Statistical Analysis
Author: Todd D. Little
Publisher: Oxford University Press
Total Pages: 784
Release: 2013-02-01
Genre: Psychology
ISBN: 0199934908

Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.

Twin Mythconceptions

Twin Mythconceptions
Author: Nancy L. Segal
Publisher: Academic Press
Total Pages: 336
Release: 2017-02-08
Genre: Psychology
ISBN: 0128039957

Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins sheds new light on over 70 commonly held ideas and beliefs about the origins and development of identical and fraternal twins. Using the latest scientific findings from psychology, psychiatry, biology, and education, the book separates fact from fiction. Each idea about twins is described, followed by both a short answer about the truth, and then a longer, more detailed explanation. Coverage includes embryology of twins, twin types, intellectual growth, personality traits, sexual orientation of twins, marital relationships, epigenetic analyses, and more. Five appendices cover selected topics in greater depth, such as the frequency of different twin types and the varieties of polar body twin pairs. This book will inform and entertain behavioral and life science researchers, health professionals, twins, parents of twins, and anyone interested in the fascinating topic of twins. - Identifies common misunderstandings about twins - Provides scientific answers to questions about twins - Encompasses the biology, psychology, genetics, and personality of twins - Includes discussion of identical, fraternal same-sex, and fraternal opposite-sex twins - Allows for quick answers to common questions and more detailed explanations

Born Together—Reared Apart

Born Together—Reared Apart
Author: Nancy L. Segal
Publisher: Harvard University Press
Total Pages: 417
Release: 2012-06-18
Genre: Psychology
ISBN: 0674065158

The Minnesota Study of Twins Reared Apart startled scientists by demonstrating that twins reared apart are as alike, across a number of personality traits and other measures, as those raised together, suggesting that genetic influence is pervasive. Segal offers an overview of the study’s scientific contributions and effect on public consciousness.

Methodology for Genetic Studies of Twins and Families

Methodology for Genetic Studies of Twins and Families
Author: M. Neale
Publisher: Springer Science & Business Media
Total Pages: 503
Release: 2013-03-09
Genre: Medical
ISBN: 9401580189

Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

The Wiley Encyclopedia of Personality and Individual Differences, Set

The Wiley Encyclopedia of Personality and Individual Differences, Set
Author:
Publisher: John Wiley & Sons
Total Pages: 4768
Release: 2020-11-04
Genre: Psychology
ISBN: 1119793955

The Encyclopedia of Personality and Individual Differences (EPID) beschäftigt sich in vier Bänden mit Gemeinsamkeiten und Unterschieden bei Individuen. Jeder Band konzentriert sich auf einen wichtigen Themenbereich bei der Untersuchung der Persönlichkeitspsychologie und den Unterschieden von Individuen. Der erste Band mit dem Titel Models and Theories betrachtet die wichtigsten klassischen und modernen Standpunkte, Perspektiven, Modelle und theoretischen Ansätze im Studium der Persönlichkeit und Unterschiede von Individuen. Der zweite Band, Measurement and Assessment, untersucht die wesentlichen klassischen und modernen Beurteilungsmethoden und -techniken. Der dritte Band mit dem Titel Personality Processes and Individual Differences erläutert die traditionellen und aktuellen Dimensionen, Konstrukte und Merkmale der Studienrichtung. Im vierten Band werden drei Hauptkategorien behandelt: klinische Zuarbeit, angewandte Forschung und interkulturelle Betrachtungen. Darüber hinaus werden Themen wie Kultur und Identität, multikulturelle Identitäten, interkulturelle Untersuchungen von Merkmalsstrukturen und Personalitätsprozesses u. v. m. behandelt. - Jeder Band enthält rund 100 Einträge zu Personalität und individuellen Unterschieden. Die Beiträge stammen von international führenden Psychologen. - Beschäftigt sich mit wichtigen klassischen und zeitgenössischen Modellen und Theorien der Persönlichkeitspsychologie, mit Mess- und Beurteilungsverfahren, Personalitätsprozessen und Unterschieden bei Individuen sowie mit Forschungsansätzen. - Bietet einen umfassenden und ausführlichen Überblick über die Persönlichkeitspsychologie. - The Encyclopedia of Personality and Individual Differences ist ein wichtiges Referenzwerk für Studenten der Psychologie und Fachexperten, die sich mit der Untersuchung und Erforschung von Persönlichkeit beschäftigen.

Developmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins
Author: Alexandra Matias
Publisher: Academic Press
Total Pages: 387
Release: 2020-05-15
Genre: Medical
ISBN: 0128203072

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. - Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management - Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis - Features contributions from international experts in twin genetics and developmental biology

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
Author: Thomas Lehner
Publisher: Academic Press
Total Pages: 798
Release: 2016-06-07
Genre: Science
ISBN: 0128005300

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. - Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics - Identifies key concepts, methods, and findings - Includes coverage of multiple disorders from autism to schizophrenia - Reviews specific genes associated with disorders - Discusses the genetic architecture of these syndromes - Explains how recent findings are influencing the understanding of biology - Clarifies the promise of these findings for future treatment

Functional Neuromarkers for Psychiatry

Functional Neuromarkers for Psychiatry
Author: Juri D. Kropotov
Publisher: Academic Press
Total Pages: 500
Release: 2016-05-03
Genre: Science
ISBN: 0124105203

Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results. - Identifies specific brain activation patterns that are neuromarkers for psychiatric disorders - Includes neuromarkers as seen via fMRI, PET, qEEG, and ERPs - Addresses neuromarkers for ADHD, schizophrenia, and OCD in detail - Provides information on using neuromarkers for diagnosis and/or personalized treatment

No Two Alike: Human Nature and Human Individuality

No Two Alike: Human Nature and Human Individuality
Author: Judith Rich Harris
Publisher: W. W. Norton & Company
Total Pages: 343
Release: 2010-02-15
Genre: Psychology
ISBN: 0393079511

"A display of scientific courage and imagination." —William Saletan, New York Times Book Review Why do people—even identical twins reared in the same home—differ so much in personality? Armed with an inquiring mind and insights from evolutionary psychology, Judith Rich Harris sets out to solve the mystery of human individuality.