The Imprinted Brain
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| Author | : Christopher Badcock |
| Publisher | : Jessica Kingsley Publishers |
| Total Pages | : 260 |
| Release | : 2009-05-15 |
| Genre | : Psychology |
| ISBN | : 1846429501 |
The Imprinted Brain sets out a radical new theory of the mind and mental illness based on the recent discovery of genomic imprinting. Imprinted genes are those from one parent that, in that parent's interest, are expressed in an offspring rather than the diametrically opposed genes from the other parent. For example, a higher birth weight may represent the dominance of the father's genes in leading to a healthy child, whereas a lower birth weight is beneficial to the mother's immediate wellbeing, and the imprint of the mother's genes will result in a smaller baby. According to this view, a win for the father's genes may result in autism, whereas one for the mother's may result in psychosis. A state of equilibrium - normality - is the most likely outcome, with a no-win situation of balanced expression. Imprinted genes typically produce symptoms that are opposites of each other, and the author uses psychiatric case material to show how many of the symptoms of psychosis can be shown to be the mental mirror-images of those of autism. Combining psychiatry with insights from modern genetics and cognitive science, Christopher Badcock explains the fascinating imprinted brain theory to the reader in a thorough but accessible way. This new theory casts some intriguing new light on other topics as diverse as the nature of genius, the appeal of detective fiction, and the successes - and failures - of psychoanalysis. This thought-provoking book is a must-read for anyone with an interest in autism, psychiatry, cognitive science or psychology in general.
| Author | : Adrianus Aertsen |
| Publisher | : Elsevier |
| Total Pages | : 309 |
| Release | : 1996 |
| Genre | : Computers |
| ISBN | : 0444820469 |
Hardbound. The present collection of papers focuses on the subject of vision. The papers bring together new insights and facts from various branches of experimental and theoretical neuroscience. The experimental facts presented in the volume stem from disparate fields, such as neuroanatomy, electrophysiology, optical imaging and psychophysics. The theoretical models in part are unsophisticated, yet still inspiring, while others skilfully apply advanced mathematical reasoning to results of experimental measurements. The book is the fifth in a series of volumes intending to define a theory of the brain by bringing together formal reasoning and experimental facts. The reader is thus being introduced to a new kind of brain science, where facts and theory are beginning to blend together.
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| Publisher | : |
| Total Pages | : |
| Release | : 2019 |
| Genre | : |
| ISBN | : 9789985588666 |
| Author | : Joseph D. Buxbaum |
| Publisher | : Academic Press |
| Total Pages | : 494 |
| Release | : 2012-10-25 |
| Genre | : Medical |
| ISBN | : 012391924X |
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
| Author | : Arnold H. Modell |
| Publisher | : MIT Press |
| Total Pages | : 284 |
| Release | : 2003 |
| Genre | : Body, Mind & Spirit |
| ISBN | : 9780262134255 |
An exploration of the biology of meaning that integrates the role of subjective processes with current knowledge of brain/mind function.
| Author | : Douglas Wahlsten |
| Publisher | : Academic Press |
| Total Pages | : 300 |
| Release | : 2019-03-19 |
| Genre | : Medical |
| ISBN | : 0128128321 |
Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior.
| Author | : Carlo Sala |
| Publisher | : Academic Press |
| Total Pages | : 396 |
| Release | : 2016-04-30 |
| Genre | : Medical |
| ISBN | : 0128005335 |
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. - Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities - Describes the genes implicated in autistic spectrum disorders and their function - Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies - Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture
| Author | : Simon LeVay |
| Publisher | : MIT Press |
| Total Pages | : 196 |
| Release | : 1994-07-25 |
| Genre | : Medical |
| ISBN | : 9780262620932 |
Written with the same clarity, directness, and humor that have made Simon LeVay one of the most popular lecturers at Harvard Medical School and at the University of California, San Diego, The Sexual Brain examines the biological roots of human sexual behavior. It puts forward the compelling case that the diversity of human sexual feelings and behavior can best be understood in terms of the development, structure, and function of the brain circuits that produce them. Discarding all preconceptions about the motivation and purpose of sexuality, LeVay discusses the scientific evidence bearing on such questions as why we are sexual animals, what the brain mechanisms are that produce sexual behavior, how these mechanisms differ between men and women and how these differences develop, and finally, what determines a person's sexual orientation: genes, prenatal events, family environment, or early sexual experiences? The Sexual Brain is broad in scope, covering evolutionary theory, molecular genetics, endocrinology, brain structure and function, cognitive psychology, and development. It is unified by LeVay's thesis that human sexual behavior, in all its diversity, is rooted in biological mechanisms that can be explored by laboratory science. The book does not shy away from the complexities of the field, but it can be readily appreciated and enjoyed by anyone with an intelligent interest in sex.
| Author | : Kevin J. Mitchell |
| Publisher | : Princeton University Press |
| Total Pages | : 305 |
| Release | : 2020-03-31 |
| Genre | : Psychology |
| ISBN | : 0691204152 |
"What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.
| Author | : Ira B. Black |
| Publisher | : MIT Press |
| Total Pages | : 254 |
| Release | : 1994 |
| Genre | : Molecular neurobiology |
| ISBN | : 9780262521888 |
Drawing on his considerable experience as a neuroscientist and clinical neurologist, Ira Black systematically disentangles the labyrinth of brain and mind in a new concept of mind that relates environment, brain genes, molecular symbols, behavior and mentation. He describes the unity of brain, mind, and experience with singular clarity, showing how mental function, brain function, and biologic information are now comprehensible in molecular terms.Writing in a clear and often conversational style, Black defines the molecular biology and biochemistry of information processing in the nervous system and describes in detail the environmental regulation of brain genes that encode molecular symbols. His coherent vision of the vast biological information system provides insight into questions of how the mind is related to the brain, what constitutes the substance of thought or the physical bases of memory, how experience changes mind function or environmental information is converted into neural language, and what biochemical abnormalities lead to Alzheimer's disease, Parkinson's disease, and schizophrenia.Information in the Brain identifies common concepts and themes in widely diverse fields, revealing the extraordinary scope of modern neuroscience, and makes central issues in the brain sciences accessible to a variety of readers. Black's description of the critical role that gene structure plays in ongoing brain and mind function will appeal to molecular biologists. Protein chemists will understand how molecular structure is translated into behavior and mentation. Neuroscientists will gain an explicit understanding of the central questions in psychology. In turn, psychologists will find new ideas concerning cellular and molecular bases of brain function and clinical neurologists and psychiatrists will discover new formulations of the pathogenesis of disease at genomic, molecular, and systems levels.Ira B. Black is Professor and Chairman, Department of Neuroscience and Cell Biology, the Robert Wood Johnson Medical School/UMDNJ.
