Historians of the intellectual and literary culture of the Enlightenment have recognised the importance of Andrew Millar (1705-68). His publisher's imprint adorned the title-pages of the most important works of the eighteenth century, in fiction, poetry, drama, medicine, and philosophy. This is the first extended study of Millar's commercial and social role in the commissioning, production, circulation, and consumption of Enlightenment literature in Britain. Providing a new intervention on the culture of Enlightenment this study shows how and why Millar provoked major controversies through his role as friend, patron, and publisher to great rivals in the republic of letters. An unprecedent analysis of publishing and authorship at the intersection of politics, business, visual arts, moral debate, and literary self-fashioning, this study of Andrew Millar also shows the degree to which Scottish identity shaped a professional career within London's rise as the cosmopolitan centre of learning and trade at the heart of the British empire. This volume presents hundreds of previously unpublished letters that passed between Millar and his literary network, and includes the 52 letters that passed between Millar and David Hume, the majority of which have been edited for the first time since 1931. This is a major contribution to the material and intellectual worlds that defined the culture of Enlightenment in Britain during the eighteenth century, casting new light in the history of publishing and authorship.