The Essential Synthesis
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| Author | : Ruben Vardanyan |
| Publisher | : Elsevier |
| Total Pages | : 635 |
| Release | : 2006-03-10 |
| Genre | : Medical |
| ISBN | : 008046212X |
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references
| Author | : C. N. R. Rao |
| Publisher | : John Wiley & Sons |
| Total Pages | : 231 |
| Release | : 2015-04-06 |
| Genre | : Science |
| ISBN | : 111883254X |
This compact handbook describes all the important methods of synthesis employed today for synthesizing inorganic materials. Some features: Focuses on modern inorganic materials with applications in nanotechnology, energy materials, and sustainability Synthesis is a crucial component of materials science and technology; this book provides a simple introduction as well as an updated description of methods Written in a very simple style, providing references to the literature to get details of the methods of preparation when required
| Author | : Garry Procter |
| Publisher | : Oxford University Press on Demand |
| Total Pages | : 237 |
| Release | : 1996 |
| Genre | : Science |
| ISBN | : 9780198557258 |
This book covers a wide range of reactions which are of importance in the asymmetric synthesis of organic compounds. The principles of asymmetric additions to carbonyls, enolate alkylation, aldol reactions, additions to C-C double bonds, reduction and oxidation, rearrangements, and hydrolysis/ esterification reactions are covered, and selected examples used to illustrated the various topics. Numerous references to original literature should be of ues to organic chemists interested in the area of asymmetric synthesis.
| Author | : Judy Jacka |
| Publisher | : Hampton Roads Publishing |
| Total Pages | : 513 |
| Release | : 2003-06-01 |
| Genre | : Body, Mind & Spirit |
| ISBN | : 1612831958 |
Throughout her thirty years as a naturopath, consultant, and educator in natural therapies, Judy Jacka has pursued a quest to understand the inner or subjective causes for disease. In her clinical practice in Australia, she combines Esoteric Healing based on her metaphysical studies with natural therapies. Her latest book is a synthesis of natural therapies and Esoteric Healing written with the aim of inspiring healers and patients to become truly holistic. The book is divided into two sections with both theory to introduce the reader to Jacka’s concept, and practice, which is loaded with case studies illustrating both the health problems and their solutions. The resolution of outer causes such as internal pollution, poor nutrition, and inherited predispositions are described in the theory section with an analysis of the role for mineral, vitamin, herbal, and homeopathic treatment. The theory section then delineates the inner causes involving the etheric/energy body and chakra disturbances. The meaning of soul as the main healing factor is explored and explained. Inner factors conditioning health and disease include those subtle states of consciousness that condition the chakras and electromagnetic fields underlying our physical organs. Part 2 is divided into sections that correlate to the main systems of the body such as the immune system, gastrointestinal system, circulatory system, and nervous system. The case histories for each section describe both the physical remedies and subtle healing techniques used and the subsequent progress of each client. *Contains numerous practical exercises to promote truly holistic healing *Judy Jacka, with over 30 years experiences, presents a system for understanding and treating both the inner and outer causes of disease
| Author | : K. C. Nicolaou |
| Publisher | : John Wiley & Sons |
| Total Pages | : 826 |
| Release | : 1996-04-11 |
| Genre | : Science |
| ISBN | : 3527292314 |
K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.
| Author | : Laurie S. Starkey |
| Publisher | : John Wiley & Sons |
| Total Pages | : 360 |
| Release | : 2012-01-18 |
| Genre | : Science |
| ISBN | : 1118180852 |
The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
| Author | : James Beauchamp |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 348 |
| Release | : 2007-08-30 |
| Genre | : Science |
| ISBN | : 038732576X |
This book contains a complete and accurate mathematical treatment of the sounds of music with an emphasis on musical timbre. The book spans the range from tutorial introduction to advanced research and application to speculative assessment of its various techniques. All the contributors use a generalized additive sine wave model for describing musical timbre which gives a conceptual unity, but is of sufficient utility to be adapted to many different tasks.
| Author | : Ruben Vardanyan |
| Publisher | : Academic Press |
| Total Pages | : 870 |
| Release | : 2016-01-07 |
| Genre | : Medical |
| ISBN | : 0124115241 |
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
| Author | : Manfred Schlosser |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1028 |
| Release | : 2013-04-15 |
| Genre | : Science |
| ISBN | : 047012217X |
WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.
| Author | : John McGrail |
| Publisher | : Red Wheel/Weiser |
| Total Pages | : 240 |
| Release | : 2012-03-22 |
| Genre | : Body, Mind & Spirit |
| ISBN | : 1601636121 |
For far too many of us, modern life is a struggle. We are stressed, depressed, anxious, addicted, obese, terrified, and angry. Are we doomed to live this way? Dr. John McGrail answers with an emphatic: “No. Anyone and everyone can create the life of their dreams.” In The Synthesis Effect he shows you how, sharing his unique process in an engaging, friendly narrative that includes stories of real people overcoming real issues and empowering their lives quickly and profoundly. The Synthesis Effect will show you: How you became you—your personality, values, feelings, habits, beliefs, and behaviors—how you create your own reality, and why it’s so difficult to change it. That you already have everything you need within you to change and transform your life, and how to use the models, tools, techniques, and exercises of Synthesis to do so. How to reach “practical enlightenment,” living your life virtually free of suffering...and how to pass it on to others. The Synthesis Effect provides simple, powerful, and clinically proven techniques for creating personal change and transformation while outlining a realistic roadmap to help us rediscover our power, save ourselves, and save our planet.
