The Elucidation Of Mechanism And Transition State Structure For Enzyme And Non Enzyme Catalyzed Reactions With The Aid Of Novel Methods For The Measurement Of Oxygen 18 Isotope Effects
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Comprehensive Dissertation Index
| Author | : |
| Publisher | : |
| Total Pages | : 818 |
| Release | : 1984 |
| Genre | : Dissertations, Academic |
| ISBN | : |
Vols. for 1973- include the following subject areas: Biological sciences, Agriculture, Chemistry, Environmental sciences, Health sciences, Engineering, Mathematics and statistics, Earth sciences, Physics, Education, Psychology, Sociology, Anthropology, History, Law & political science, Business & economics, Geography & regional planning, Language & literature, Fine arts, Library & information science, Mass communications, Music, Philosophy and Religion.
Comprehensive Dissertation Index
| Author | : University Microfilms International |
| Publisher | : Ann Arbor, Mich. : University Microfilms International |
| Total Pages | : 712 |
| Release | : 1984 |
| Genre | : Reference |
| ISBN | : |
Transition States in Biological Chemistry
| Author | : G. Michael Blackburn |
| Publisher | : |
| Total Pages | : 300 |
| Release | : 2020-05-14 |
| Genre | : Science |
| ISBN | : 9781788017961 |
Transition states play a significant role in the function of enzymes, but to make use of this fact in the design of novel catalysts it is necessary to understand the underlying chemistry of these states. Although other texts touch upon transitions states in relation to enzymes and catalysis this is the first to provide a focused and comprehensive overview of the topic. It discusses how an understanding of transition states impacts drug discovery and the engineering of novel biocatalysts, and highlights key problems in the field that remain to be addressed. Combining both computational and experimental research, this accessible text is a useful reference for those studying enzyme catalysed reactions at a postgraduate level, as well as being a handy primer for the more advanced researcher.
Theoretical Studies of Transition States and Reaction Mechanisms in Solvent and Enzyme Catalyzed Reactions
| Author | : Renán Cárdenas Marín |
| Publisher | : |
| Total Pages | : 61 |
| Release | : 1992 |
| Genre | : Enzyme kinetics |
| ISBN | : 9789157644916 |
New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions
| Author | : Gertz I. Likhtenshtein |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 244 |
| Release | : 2003 |
| Genre | : Science |
| ISBN | : 9781402010064 |
Enzyme catalysis is an important and vigorously developing field of basic and applied research, posing challenging problems to biochemists and chemists. This volume embraces modern areas of enzyme catalysis where other books in the field concentrate mainly on kinetic, bioorganic and biochemical aspects of the enzyme catalysis and do not cover biophysical and physicochemical problems. Topics covered include: modern physical and kinetic methods of investigation;contemporary theories of elementary chemical processes in enzymes; structure, dynamics and action mechanism of enzyme active sites; concept of pretransition state; theory of long-range electron transfer and proton translocation;mechanisms of tough biochemical reactions (dinitrogen reduction, light energy conversation, water photooxidation, hydroxilation);the achievements and problems of biomimetic chemical reactions.
Dynamics in Enzyme Catalysis
| Author | : Judith Klinman |
| Publisher | : Springer |
| Total Pages | : 217 |
| Release | : 2013-09-14 |
| Genre | : Science |
| ISBN | : 3642389627 |
Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole, A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov, Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.
