This timely Companion provides a comprehensive overview of the relationship between applied ethics and the development and use of Artificial Intelligence (AI). Adopting a holistic approach, an array of global experts identify the norms at stake, map the legal landscape, and contextualize normative expectations in relevant use cases of AI. The Elgar Companion to Applied AI Ethics explores the principles and notions that stakeholders confront in the development and implementation of AI technologies. Chapters examine the EU and US approaches to AI legalization, and question the extent to which different legal strategies adopted by Western governments foster a common international understanding of AI regulation. Diverse case studies of applied AI are discussed, covering autonomous driving, digital finance, AI and education, virtual cities, video games, and social robots. Ultimately, the Companion emphasizes the importance of incorporating non-Western perspectives into the global discourse on AI ethics and highlights the need to create effective frameworks which prevent AI solutions from negatively impacting individuals' mental health. This Companion is an invaluable resource for legal students and academics working in AI, information technology, social sciences, computer sciences, and human rights. Its practical implications for the future of technology will also be of interest to professionals working in international public policy and management staff concerned with digital ethics.