Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles
Author: Eric Marsault
Publisher: John Wiley & Sons
Total Pages: 617
Release: 2017-09-12
Genre: Science
ISBN: 1119092566

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Macrocycles in Drug Discovery

Macrocycles in Drug Discovery
Author: Jeremy I Levin
Publisher: Royal Society of Chemistry
Total Pages: 526
Release: 2015
Genre: Medical
ISBN: 1849737010

This series provides a comprehensive resource for postgraduate students and for scientists in academia or industry wanting to learn topics outside their own areas of expertise.

Anion Receptor Chemistry

Anion Receptor Chemistry
Author: Jonathan L Sessler
Publisher: Royal Society of Chemistry
Total Pages: 431
Release: 2007-10-31
Genre: Science
ISBN: 1847552471

Anion recognition plays a critical role in a range of biological processes, and a variety of receptors and carriers can be found throughout the natural world. Chemists working in the area of supramolecular chemistry have created a range of anion receptors, drawing inspiration from nature as well as their own inventive processes. This book traces the origins of anion recognition chemistry as a unique sub-field in supramolecular chemistry while illustrating the basic approaches currently being used to effect receptor design. The combination of biological overview and summary of current synthetic approaches provides a coverage that is both comprehensive and comprehensible. First, the authors detail the key design motifs that have been used to generate synthetic receptors and which are likely to provide the basis for further developments. They also highlight briefly some of the features that are present in naturally occurring anion recognition and transport systems and summarise the applications of anion recognition chemistry. Providing as it does a detailed review for practitioners in the field and a concise introduction to the topic for newcomers, Anion Receptor Chemistry reflects the current state of the art. Fully referenced and illustrated in colour, it is a welcome addition to the literature.

Anion Coordination Chemistry

Anion Coordination Chemistry
Author: Kristin Bowman-James
Publisher: John Wiley & Sons
Total Pages: 644
Release: 2012-03-27
Genre: Science
ISBN: 3527639519

Building on the pioneering work in supramolecular chemistry from the last 20 years or so, this monograph addresses new and recent approaches to anion coordination chemistry. Synthesis of receptors, biological receptors and metallareceptors, the energetics of anion binding, molecular structures of anion complexes, sensing devices are presented and computational studies addressed to aid with the understanding of the different driving forces responsible for anion complexation. The reader is promised an actual picture of the state of the art for this exciting and constantly evolving field of supramolecular anion coordination chemistry. The topics range from ion channels to selective sensors, making it attractive to all researchers and PhD students with an interest in supramolecular chemistry.

Macrocyclic Chemistry

Macrocyclic Chemistry
Author: K. Gloe
Publisher: Springer Science & Business Media
Total Pages: 450
Release: 2005-12-05
Genre: Science
ISBN: 1402036876

Macrocyclic Chemistry: Current Trends and Future Perspectives illustrates essential concepts in this expanding research field covering both basic and applied studies. Written by well-known experts from around the world, the topics of the chapters range from new macrocyclic architectures with different functions and self-assembly processes through to the modeling and dynamics of such systems. The content also reflects on application possibilities in analytical chemistry, separation processes, material preparation and medicine. Thus this book serves as a creative source of research strategies and methodic tools. Providing an excellent overview of the field, this book will be a valuable resource for researchers in industry and academic institutions as well as for teachers of science and graduate students. This book is devoted to the long-standing tradition of the International Symposia on Macrocyclic Chemistry (ISMC) and published to coincide with the 30th meeting, Dresden, Germany.

Cucurbiturils and Related Macrocycles

Cucurbiturils and Related Macrocycles
Author: Kimoon Kim
Publisher: Royal Society of Chemistry
Total Pages: 572
Release: 2019-11-06
Genre: Science
ISBN: 1788015002

This book provides a complete overview of cucurbituril chemistry, covering fundamental aspects including history, synthesis and host-guest chemistry.

Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles
Author: Eric Marsault
Publisher: John Wiley & Sons
Total Pages: 653
Release: 2017-08-03
Genre: Science
ISBN: 1119092582

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Supramolecular Coordination Complexes

Supramolecular Coordination Complexes
Author: Sankarasekaran Shanmugaraju
Publisher: Elsevier
Total Pages: 498
Release: 2022-10-28
Genre: Science
ISBN: 0323907059

Supramolecular Coordination Complexes: Design, Synthesis, and Applications discusses the growth of the field and explores the advantages, opportunities and latest applications of supramolecular complexes. Beginning with an introduction to design principles, synthetic methods, and post-synthetic functionalization of supramolecular complexes, the book goes on to compile the different analytical and computational modeling methods used to understand the structure and functional properties of supramolecular structures. Applications of supramolecular complexes in biomedicine, sensing, catalysis and materials are then explored in detail. Drawing on the knowledge of a global team of experts, this book provides a wealth of interesting information for students and researchers working in the design, synthesis or application of such complexes. Discusses cutting-edge approaches for the investigation of supramolecular coordination chemistry Summarizes a varied range of supramolecular coordination, complex designs and applications Highlights the interdisciplinary connections between supramolecular chemistry and the fields of biology and materials science