The Cytoskeletal Protein Adducin And Its Role In Vascular Smooth Muscle
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| Author | : Jose C. Jimenez-Lopez |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 344 |
| Release | : 2017-05-17 |
| Genre | : Science |
| ISBN | : 9535131699 |
The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.
| Author | : Martin P. Schwellnus |
| Publisher | : John Wiley & Sons |
| Total Pages | : 624 |
| Release | : 2009-01-26 |
| Genre | : Medical |
| ISBN | : 9781444300642 |
This comprehensive new volume in the Encyclopaedia of SportsMedicine series, published under the auspices of the InternationalOlympic Committee, delivers an up-to-date, state of the artpresentation of the medical conditions that athletes may sufferfrom during training and competition. Presented in a clear style and format, The Olympic Textbookof Medicine in Sport, covers not only the basic approach totraining, monitoring training and the clinical implications ofexcessive training, but also deals with all the major systems inthe body, and focuses on medical conditions that athletes maysuffer from in each system. Medical conditions in athletes withdisabilities, genetics and exercise and emergency sports medicineare also uniquely examined. The Olympic Textbook of Medicine in Sport draws on theexpertise of an international collection of contributors who arerecognized as leaders in their respective fields. The systematic approach followed in the book will make itinvaluable to all medical doctors and other health personnel whoserve athletes and sports teams. Sports practitioners are providedwith a clinical approach to the prevention, diagnosis and treatmentof common and less common medical problems encountered by athletes.This volume should be kept close at hand for frequentconsultation.
| Author | : Kwang W. Jeon |
| Publisher | : Academic Press |
| Total Pages | : 341 |
| Release | : 2012-03-07 |
| Genre | : Science |
| ISBN | : 0123943051 |
Presents current advances and comprehensive reviews in cell biology--both plant and animal.
| Author | : Philippe Jeanteur |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 242 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 3642585914 |
The internal structure of a cell can be affected by signals in the form of small molecules outside the cell. These changes can then alter the shape or adhesiveness of the cell. This volume centers particularly on one family of cellular proteins which transmit these signals, the Rho Ras-like GTPases, and examines their role in normal cellular processes and development. Also discussed are their roles in cancer formation and microbial pathogenesis.
| Author | : Kermit L. Carraway |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 293 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 3662129930 |
This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?
| Author | : |
| Publisher | : |
| Total Pages | : 2036 |
| Release | : 2004 |
| Genre | : Medicine |
| ISBN | : |
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
| Author | : José Marín-García |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 511 |
| Release | : 2011-06-21 |
| Genre | : Medical |
| ISBN | : 1441994610 |
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
| Author | : Paolo Mulatero |
| Publisher | : MDPI |
| Total Pages | : 200 |
| Release | : 2021-01-21 |
| Genre | : Science |
| ISBN | : 3039366270 |
Arterial hypertension affects about 1 billion people worldwide and it is the strongest modifiable risk factor for cardiovascular disease and related disability. Since the initial discovery of rare monogenic disorders with large effects, the role of genomics has evolved into large genome-wide association studies detecting common variants with a modest effect size. Similarly, pharmacogenomics has emerged as a new tool for understanding variability in drug response, to maximize efficacy and reduce toxicity. This book presents the most recent advances in the field of genetics and genomics of arterial hypertension and their potential impact on clinical management. The book is a useful tool for clinicians but also to the research community and those who want to be updated in the field.
| Author | : Leonard S. Lilly |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 917 |
| Release | : 2020-05-26 |
| Genre | : Medical |
| ISBN | : 1975120604 |
Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management.
| Author | : Joseph Flynn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 597 |
| Release | : 2013-06-26 |
| Genre | : Medical |
| ISBN | : 1627034900 |
The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.
