The Chemistry Of Microbiomes
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| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 133 |
| Release | : 2017-07-19 |
| Genre | : Science |
| ISBN | : 0309458390 |
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 133 |
| Release | : 2017-08-19 |
| Genre | : Science |
| ISBN | : 0309458366 |
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 318 |
| Release | : 2017-10-06 |
| Genre | : Science |
| ISBN | : 0309449839 |
People's desire to understand the environments in which they live is a natural one. People spend most of their time in spaces and structures designed, built, and managed by humans, and it is estimated that people in developed countries now spend 90 percent of their lives indoors. As people move from homes to workplaces, traveling in cars and on transit systems, microorganisms are continually with and around them. The human-associated microbes that are shed, along with the human behaviors that affect their transport and removal, make significant contributions to the diversity of the indoor microbiome. The characteristics of "healthy" indoor environments cannot yet be defined, nor do microbial, clinical, and building researchers yet understand how to modify features of indoor environmentsâ€"such as building ventilation systems and the chemistry of building materialsâ€"in ways that would have predictable impacts on microbial communities to promote health and prevent disease. The factors that affect the environments within buildings, the ways in which building characteristics influence the composition and function of indoor microbial communities, and the ways in which these microbial communities relate to human health and well-being are extraordinarily complex and can be explored only as a dynamic, interconnected ecosystem by engaging the fields of microbial biology and ecology, chemistry, building science, and human physiology. This report reviews what is known about the intersection of these disciplines, and how new tools may facilitate advances in understanding the ecosystem of built environments, indoor microbiomes, and effects on human health and well-being. It offers a research agenda to generate the information needed so that stakeholders with an interest in understanding the impacts of built environments will be able to make more informed decisions.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 123 |
| Release | : 2018-03-01 |
| Genre | : Science |
| ISBN | : 0309468698 |
A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.
| Author | : Food Forum |
| Publisher | : National Academies Press |
| Total Pages | : 197 |
| Release | : 2013-02-27 |
| Genre | : Medical |
| ISBN | : 030926586X |
The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.
| Author | : Joseph F Pierre |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 213 |
| Release | : 2022-07-01 |
| Genre | : Science |
| ISBN | : 178801748X |
Bringing together expert researchers in the fields of microbiome, metabolism, and nutrition research, this book compiles the current state of knowledge from authorities specifically on how diet regulates microbial function with metabolic implications for the human host. Chapters cover the broad concepts of microbial-host interactions under the dietary influences of specific macronutrients, micronutrients, small molecule generation and bile acid circulation, with inclusion of later clinical chapters encompassing topics like bariatric surgery and our current understanding of probiotics, prebiotics, and synbiotics. Covering a timely topic from a functional standpoint, the book fills a gap in the existing literature. While increased attention is placed on descriptive work, it will importantly highlight emerging functional and mechanistic research findings that illustrate the inner workings of the dietary-microbial-host orchestration of metabolic regulation. Providing an exciting summary of the importance of current microbial function, it will also summarize the next major directions in the field of microbiome research.
| Author | : Rob DeSalle |
| Publisher | : Yale University Press |
| Total Pages | : 260 |
| Release | : 2015-01-01 |
| Genre | : Medical |
| ISBN | : 0300208405 |
Inspired by an exhibition at the American Museum of Natural History in New York, explores microbes and their implications for modern science and medicine.
| Author | : Manoj Kumar Solanki |
| Publisher | : Academic Press |
| Total Pages | : 520 |
| Release | : 2020-08-28 |
| Genre | : Science |
| ISBN | : 0128226013 |
Microbiomes and Plant Health: Panoply and Their Applications includes the most recent advances in phytobiome research. The book emphasizes the use of modern molecular tools such as smart delivery systems for microbiol inoculation, next-generation sequencing, and genome mapping. Chapters discuss a variety of applications and examples, including the sugarcane microbiome, rhizoengineering, nutrient recycling, sustainable agricultural practices and bio-potential of herbal medicinal plants. Written by a range of experts with real-world practical insights, this title is sure to be an essential read for plant and soil microbiologists, phytopathologists, agronomists, and researchers interested in sustainable forestry and agriculture practices. - Offers readers a one-stop resource on the topic of plant and soil microbiome and their applications in plant disease, sustainable agriculture, soil health and medicinal plants - Addresses the role of phytobiome to combat biotic and abiotic factors - Emphasizes the use of modern molecular tools such as smart delivery systems for microbial inoculation, next-generation sequencing and genome mapping
| Author | : Trevor C. Charles |
| Publisher | : Springer |
| Total Pages | : 256 |
| Release | : 2017-10-09 |
| Genre | : Science |
| ISBN | : 3319615106 |
In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.
| Author | : Ed Yong |
| Publisher | : HarperCollins |
| Total Pages | : 285 |
| Release | : 2016-08-09 |
| Genre | : Science |
| ISBN | : 0062368621 |
New York Times Bestseller New York Times Notable Book of 2016 • NPR Great Read of 2016 • Named a Best Book of 2016 by The Economist, Smithsonian, NPR's Science Friday, MPR, Minnesota Star Tribune, Kirkus Reviews, Publishers Weekly, The Guardian, Times (London) From Pulitzer Prize winner Ed Yong, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since Darwin—a “microbe’s-eye view” of the world that reveals a marvelous, radically reconceived picture of life on earth. Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Pulitzer Prize-winning author Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.
