Intracellular Cholesterol Trafficking

Intracellular Cholesterol Trafficking
Author: T.Y. Chang
Publisher: Springer Science & Business Media
Total Pages: 298
Release: 2012-12-06
Genre: Science
ISBN: 1461551137

INTRODUCTION AND RATIONALE FOR INTRACELLULAR CHOLESTEROL TRAFFICKING This volume is an elaboration of an earlier small meeting held in St. Louis, Missouri. In April 1997, many of the authors met for a two-day meeting devoted entirely to intracellular cholesterol trafficking. The rationale for this meeting was that investigators interested in this topic worked in a variety of fields, and rarely, if ever, all met together. Everybody knew each other's papers but mostly worked in isolation from one another. Understanding of cholesterol trafficking also appeared to have reached the point where it would start to rapidly expand beyond these few laboratories. Understanding of cholesterol trafficking was moving from a largely descriptive science into the molecular age. It seemed a good time to get together and see how much we agreed upon up to this point. More authors contributed to this volume than attended the St. Louis meeting. That meeting was generously funded by grants from Bristol-Myers Squibb, Merck and Company and Parke-Davis, however, the total funding available limited the size of the meeting. For the book, we are not so limited and have tried to be as inclusive as possible and pretty much invited everyone who is presently active in this area. We were quite fortunate to successfully recruit the authors we sought for each of these chapters. The authors and their contributions can be organized by particular interests and particular areas of expertise.

Management of Prader-Willi Syndrome

Management of Prader-Willi Syndrome
Author: Merlin G. Butler
Publisher: Springer Nature
Total Pages: 539
Release: 2022-10-10
Genre: Medical
ISBN: 3030981711

Now in a fully revised and updated fourth edition, this book remains the most comprehensive resource on Prader-Willi syndrome (PWS) available on the market. There have been significant changes in the diagnosis, clinical care and treatment of PWS since the previous edition was published in 2006, and more thorough information on understanding the cause and diagnosis of the condition, along with clinical presentation and findings with natural history data now available. The book is divided into three thematic sections. Part One discusses the genetics, diagnosis, research and overview of PWS, including current laboratory testing. The medical physiology and treatment of PWS comprise Part Two, covering the GI system, obesity as well as the use of growth hormone. Part Three, the largest section, presents a wide-ranging, multidisciplinary management approach to PWS, attending to the many manifestations of the condition. Topics here include neurodevelopmental aspects, speech and language disorders, motor issues, psychological and behavioral management, educational and transitional considerations, vocational training and residential care, and advocacy for both school discipline and sexuality. Syndrome-specific growth charts, benefits eligibility information and additional resources are included in helpful appendices. Timely and well-crafted, this latest edition of Management of Prader-Willi Syndrome remains the gold standard for clinicians and health care providers working with patients diagnosed with this rare obesity-related genetic disorder.

Multi-disciplinary Trends in Artificial Intelligence

Multi-disciplinary Trends in Artificial Intelligence
Author: Antonis Bikakis
Publisher: Springer
Total Pages: 465
Release: 2015-11-28
Genre: Computers
ISBN: 3319261819

This book constitutes the refereed conference proceedings of the 9th International Conference on Multi-disciplinary Trends in Artificial Intelligence, MIWAI 2015, held in Fuzhou, China, in November 2015. The 30 revised full papers presented together with 12 short papers were carefully reviewed and selected from 83 submissions. The papers feature a wide range of topics covering knowledge representation, reasoning, and management; multi-agent systems; data mining and machine learning; computer vision; robotics; AI in bioinformatics; AI in security and networks; and other AI applications.