The Biology Of Early Life Stress
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| Author | : Jennie G. Noll |
| Publisher | : Springer |
| Total Pages | : 178 |
| Release | : 2018-06-14 |
| Genre | : Psychology |
| ISBN | : 3319725890 |
This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma. Included in the coverage: Biological embedding of child maltreatment Toward an adaptation-based approach to resilience Developmental traumatology: brain development and maltreated children with and without PTSD Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry An integrative temporal framework for psychological resilience The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.
| Author | : Donna Jackson Nakazawa |
| Publisher | : Simon and Schuster |
| Total Pages | : 304 |
| Release | : 2016-07-26 |
| Genre | : Family & Relationships |
| ISBN | : 1476748365 |
An examination of the link between Adverse Childhood Events (ACE's) and adult illnesses.
| Author | : Ruth A. Lanius |
| Publisher | : Cambridge University Press |
| Total Pages | : 329 |
| Release | : 2010-08-05 |
| Genre | : Medical |
| ISBN | : 9780521880268 |
There is now ample evidence from the preclinical and clinical fields that early life trauma has both dramatic and long-lasting effects on neurobiological systems and functions that are involved in different forms of psychopathology as well as on health in general. To date, a comprehensive review of the recent research on the effects of early and later life trauma is lacking. This book fills an obvious gap in academic and clinical literature by providing reviews which summarize and synthesize these findings. Topics considered and discussed include the possible biological and neuropsychological effects of trauma at different epochs and their effect on health. This book will be essential reading for psychiatrists, clinical psychologists, mental health professionals, social workers, pediatricians and specialists in child development.
| Author | : Rachel Yehuda |
| Publisher | : Frontiers Media SA |
| Total Pages | : 141 |
| Release | : 2015-03-16 |
| Genre | : Diseases of the endocrine glands. Clinical endocrinology |
| ISBN | : 2889194817 |
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
| Author | : William R. Lovallo |
| Publisher | : SAGE Publications |
| Total Pages | : 366 |
| Release | : 2015-01-29 |
| Genre | : Psychology |
| ISBN | : 1483378284 |
Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.
| Author | : Daniel P. Keating |
| Publisher | : Macmillan + ORM |
| Total Pages | : 225 |
| Release | : 2017-04-11 |
| Genre | : Psychology |
| ISBN | : 146688648X |
Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations—with significant consequences. Born Anxious introduces a new word into our lexicon: “methylated.” It’s short for “epigenetic methylation,” and it offers insight into behaviors we have all observed but never understood—the boss who goes ballistic at the slightest error; the infant who can’t be calmed; the husband who can’t fall asleep at night. In each case, because of an exposure to environmental adversity in utero or during the first year of life, a key stress system has been welded into the “on” position by the methylation process, predisposing the child’s body to excessive levels of the stress hormone cortisol. The effect: lifelong, unrelenting stress and its consequences–from school failure to nerve-wracking relationships to early death. Early adversity happens in all levels of society but as income gaps widen, social inequality and fear of the future have become the new predators; in Born Anxious, Daniel P. Keating demonstrates how we can finally break the cycle.
| Author | : Joao L. de Quevedo |
| Publisher | : Academic Press |
| Total Pages | : 472 |
| Release | : 2020-11-25 |
| Genre | : Medical |
| ISBN | : 012819183X |
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
| Author | : Thomas Frodl |
| Publisher | : Academic Press |
| Total Pages | : 422 |
| Release | : 2016-03-16 |
| Genre | : Psychology |
| ISBN | : 0128026286 |
Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. - Knowledge covering the whole life span from early to later life - Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience - Understanding the neurobiology of major depressive disorder - Integrating stress and environmental factors with molecular underpinnings - More than 25 illustrations and tables
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 493 |
| Release | : 2019-07-26 |
| Genre | : Social Science |
| ISBN | : 0309490111 |
Adolescenceâ€"beginning with the onset of puberty and ending in the mid-20sâ€"is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€"rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish.
| Author | : David Costantini |
| Publisher | : Springer |
| Total Pages | : 316 |
| Release | : 2022-02-16 |
| Genre | : Science |
| ISBN | : 9783030901301 |
Development is a complex and highly dynamic process involving the cross talk among genes, maternal effects and environmental circumstances. Widespread evidence from plant to animal species show that variation in developmental conditions can modulate life history trajectories and influence key traits, such as growth, reproduction, and senescence. These effects are not limited to a single generation but can also be passed on future generations. This book aims to bring together studies of early life effects from the fields of evolutionary biology, global change biology, and biomedicine to synthesise and improve current knowledge of the mechanisms involved, and how variation in early life conditions translates into Darwinian fitness outcomes. Relying on examples of organisms’ responses to the ongoing and future environmental challenges of the Anthropocene, this book takes a novel approach to address the adaptive meaning of early life effects. The book has a broad scientific approach, targeting eco-evolutionary biologists, behavioural biologists, eco-physiologists, eco-toxicologists, as well as epidemiologists and biomedical scientists.
