The Behavioral Neurobiology Of Aging
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| Author | : Roberto Cabeza |
| Publisher | : Oxford University Press |
| Total Pages | : 633 |
| Release | : 2016-10-31 |
| Genre | : Medical |
| ISBN | : 0190660236 |
This second edition of the popular Cognitive Neuroscience of Aging provides up-to-date coverage of the most fundamental topics in this discipline. Like the first edition, this volume accessibly and comprehensively reviews the neural mechanisms of cognitive aging appropriate to both professionals and students in a variety of domains, including psychology, neuroscience, neuropsychology, neurology, and psychiatry. The chapters are organized into three sections. The first section focuses on major questions regarding methodological approaches and experimental design. It includes chapters on structural imaging (MRI, DTI), functional imaging (fMRI), and molecular imaging (dopamine PET, etc), and covers multimodal imaging, longitudinal studies, and the interpretation of imaging findings. The second section concentrates on specific cognitive abilities, including attention and inhibitory control, executive functions, memory, and emotion. The third section turns to domains with health and clinical implications, such as the emergence of cognitive deficits in middle age, the role of genetics, the effects of modulatory variables (hypertension, exercise, cognitive engagement), and the distinction between healthy aging and the effects of dementia and depression. Taken together, the chapters in this volume, written by many of the most eminent scientists as well as young stars in this discipline, provide a unified and comprehensive overview of cognitive neuroscience of aging.
| Author | : Elizabeth Head |
| Publisher | : Academic Press |
| Total Pages | : 354 |
| Release | : 2021-08-31 |
| Genre | : Medical |
| ISBN | : 0128188464 |
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. - Discusses the complexities involved with aging and Alzheimer's disease in Down syndrome - Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age - Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
| Author | : Marie-Christine Pardon |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 361 |
| Release | : 2012-04-15 |
| Genre | : Medical |
| ISBN | : 3642238750 |
This volume discusses the current state of research findings related to healthy brain aging by integrating human clinical studies and translational research in animal models. Several chapters offer a unique overview of successful aging, age-related cognitive decline and its associated structural and functional brain changes, as well as how these changes are influenced by reproductive aging. Insights provided by preclinical studies in mouse models and advanced neuroimaging techniques in humans are also presented.
| Author | : Colin R. Martin |
| Publisher | : Academic Press |
| Total Pages | : 1500 |
| Release | : 2021-07-02 |
| Genre | : Medical |
| ISBN | : 9780128183694 |
Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain including Alzheimer's, stroke, and multiple sclerosis. Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. It also examines the use of animal modelling of aging and neurological disease. Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging: Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on diagnosis and biomarkers of neurological aging, Alzheimer's, and stroke Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Focuses on neurological diseases and conditions linked to aging, environmental factors, and clinical recommendations Includes more than 500 illustrations and tables Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet: Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on the genetics influencing aging and diseases of aging Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Focuses on neurological diseases and conditions linked to aging, environmental factors, and clinical recommendations Includes more than 500 illustrations and tables
| Author | : Tobias Egner |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1070 |
| Release | : 2017-01-11 |
| Genre | : Science |
| ISBN | : 1118920473 |
Covering basic theory, new research, and intersections with adjacent fields, this is the first comprehensive reference work on cognitive control – our ability to use internal goals to guide thought and behavior. Draws together expert perspectives from a range of disciplines, including cognitive psychology, neuropsychology, neuroscience, cognitive science, and neurology Covers behavioral phenomena of cognitive control, neuroanatomical and computational models of frontal lobe function, and the interface between cognitive control and other mental processes Explores the ways in which cognitive control research can inform and enhance our understanding of brain development and neurological and psychiatric conditions
| Author | : Martin L. Albert |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 740 |
| Release | : 1994 |
| Genre | : Language Arts & Disciplines |
| ISBN | : 9780195071672 |
This thorough revision of a well-established text presents essential information on the neurobiology of aging. There are new chapters on competency and ethics, problems of daily living, psychopharmacology, and stability and falls. Written in a accessible style, this book will be invaluable to clinicians and neurologists who treat elderly patients.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 285 |
| Release | : 2000-04-18 |
| Genre | : Social Science |
| ISBN | : 0309172195 |
Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.
| Author | : Carl W. Cotman |
| Publisher | : Academic Press |
| Total Pages | : 857 |
| Release | : 2014-04-24 |
| Genre | : Psychology |
| ISBN | : 1483217566 |
Behavioral Neuroscience: An Introduction provides a basic understanding of what is known about the means by which neurons communicate and about the nervous system which interprets, integrates, and transmits signals into meaningful and appropriate behaviors. The book starts with an overview of the nervous system. The text then describes the general operation and organization of the nervous system; and some of the major types of neurons in the context of their systems. The basic characteristics of neurons and how they communicate; the processes and the basic integrative properties of defined groups of neurons; and complex learning and memory are also considered. The book further tackles the auditory, somesthetic, olfactory, gustatory, visual, and motor systems; the functions of the autonomic nervous system and the neuroendocrine system; and the neural basis of two types of motivated behavior, drinking and feeding. The text also encompasses sleep and activity rhythms; the development of the neural circuitry and its plasticity throughout life; and the development of behavior. Behavioral disorders and the aspects of the human nervous system which make man unique among all living creatures are also looked into. Behavioral psychologists, behavioral neuroscientists, and psychobiologists will find the book invaluable.
| Author | : Ayanna K. Thomas |
| Publisher | : Cambridge University Press |
| Total Pages | : 1048 |
| Release | : 2020-05-28 |
| Genre | : Psychology |
| ISBN | : 1108690742 |
Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 300 |
| Release | : 2015-07-21 |
| Genre | : Medical |
| ISBN | : 0309368650 |
For most Americans, staying "mentally sharp" as they age is a very high priority. Declines in memory and decision-making abilities may trigger fears of Alzheimer's disease or other neurodegenerative diseases. However, cognitive aging is a natural process that can have both positive and negative effects on cognitive function in older adults - effects that vary widely among individuals. At this point in time, when the older population is rapidly growing in the United States and across the globe, it is important to examine what is known about cognitive aging and to identify and promote actions that individuals, organizations, communities, and society can take to help older adults maintain and improve their cognitive health. Cognitive Aging assesses the public health dimensions of cognitive aging with an emphasis on definitions and terminology, epidemiology and surveillance, prevention and intervention, education of health professionals, and public awareness and education. This report makes specific recommendations for individuals to reduce the risks of cognitive decline with aging. Aging is inevitable, but there are actions that can be taken by individuals, families, communities, and society that may help to prevent or ameliorate the impact of aging on the brain, understand more about its impact, and help older adults live more fully and independent lives. Cognitive aging is not just an individual or a family or a health care system challenge. It is an issue that affects the fabric of society and requires actions by many and varied stakeholders. Cognitive Aging offers clear steps that individuals, families, communities, health care providers and systems, financial organizations, community groups, public health agencies, and others can take to promote cognitive health and to help older adults live fuller and more independent lives. Ultimately, this report calls for a societal commitment to cognitive aging as a public health issue that requires prompt action across many sectors.
