Basic Science Methods for Clinical Researchers

Basic Science Methods for Clinical Researchers
Author: Morteza Jalali
Publisher: Academic Press
Total Pages: 383
Release: 2017-03-31
Genre: Science
ISBN: 012803078X

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Bridging the Bed-Bench Gap

Bridging the Bed-Bench Gap
Author: National Research Council
Publisher: National Academies Press
Total Pages: 134
Release: 2004-02-05
Genre: Medical
ISBN: 0309166454

Since the 1970s there has been a serious gap between fundamental biological research and its clinical application. In response to this gap the Lucille P. Markey Charitable Trust instituted the General Organizational Grants program, which funded two types of awards to provide training that would bridge the bed-bench gap. These training awards fell into two categories: (1) those that provided significant opportunities for M.D.s to engage in basic research during and immediately following medical school and residency, and (2) those that provided significant clinical exposure for Ph.D.s while they were predoctoral or postdoctoral students. These grants were intended to close the widening gap between rapid advances in our understanding of the biological process and the translation of that knowledge into techniques for preventing diseases. This report examines the General Organizational Grant programs, identifies best practices, and provides observations for future philanthropic funders.

Teaching About Evolution and the Nature of Science

Teaching About Evolution and the Nature of Science
Author: National Academy of Sciences
Publisher: National Academies Press
Total Pages: 150
Release: 1998-05-06
Genre: Education
ISBN: 0309063647

Today many school students are shielded from one of the most important concepts in modern science: evolution. In engaging and conversational style, Teaching About Evolution and the Nature of Science provides a well-structured framework for understanding and teaching evolution. Written for teachers, parents, and community officials as well as scientists and educators, this book describes how evolution reveals both the great diversity and similarity among the Earth's organisms; it explores how scientists approach the question of evolution; and it illustrates the nature of science as a way of knowing about the natural world. In addition, the book provides answers to frequently asked questions to help readers understand many of the issues and misconceptions about evolution. The book includes sample activities for teaching about evolution and the nature of science. For example, the book includes activities that investigate fossil footprints and population growth that teachers of science can use to introduce principles of evolution. Background information, materials, and step-by-step presentations are provided for each activity. In addition, this volume: Presents the evidence for evolution, including how evolution can be observed today. Explains the nature of science through a variety of examples. Describes how science differs from other human endeavors and why evolution is one of the best avenues for helping students understand this distinction. Answers frequently asked questions about evolution. Teaching About Evolution and the Nature of Science builds on the 1996 National Science Education Standards released by the National Research Councilâ€"and offers detailed guidance on how to evaluate and choose instructional materials that support the standards. Comprehensive and practical, this book brings one of today's educational challenges into focus in a balanced and reasoned discussion. It will be of special interest to teachers of science, school administrators, and interested members of the community.

Basic Sciences for Core Medical Training and the MRCP

Basic Sciences for Core Medical Training and the MRCP
Author: Neil Herring
Publisher: Oxford University Press
Total Pages: 577
Release: 2015-10-29
Genre: Medical
ISBN: 0191068128

Providing a clear explanation of the relevant medical science behind the individual medical specialties, Basic Science for Core Medical Training and the MRCP, is an indispensable part of a candidate's MRCP preparation. Directly linked to the Royal College exam, the book follows the same systems-based approach as the syllabus for accurate and effective revision. With full coverage of basic science for the medical specialities, the book features material on genetics, cellular, molecular and membrane biology, and biochemistry. Content is presented in an illustrated and easy-to-read format, ensuring that the basic science for each medical specialty is more approachable and accessible. A focus on how the basic sciences aid understanding of clinical practice is reinforced through key tables of differential diagnoses and pharmacology. Ten multiple choice questions at the end of each chapter consolidate learning and enable candidates to test their knowledge. The book also covers common examination errors and areas of misunderstanding to aid learning and help candidates avoid common pitfalls.

Essentials of Basic Science in Surgery

Essentials of Basic Science in Surgery
Author: Edward Bruce Savage
Publisher: Lippincott Williams & Wilkins
Total Pages: 420
Release: 1993
Genre: Medical
ISBN:

Based on a program that has resulted in scores in the 99th percentile in American Board of Surgery exams...edited by surgeons who have recently passed or given the board exams, Essentials of Basic Science in Surgery will enhance the understanding of how basic science is integrated into surgery. Coverage ranges from atherosclerosis and atherogenesis and wound healing, through principles of anesthesia surgical infectious disease, radiation and chemotherapy to tumor immunobiology and pharmacology.

Basic Science Budget and SSC

Basic Science Budget and SSC
Author: United States. Congress. Senate. Committee on Energy and Natural Resources. Subcommittee on Energy Research and Development
Publisher:
Total Pages: 280
Release: 1988
Genre: Science and state
ISBN:

Ambitious Science Teaching

Ambitious Science Teaching
Author: Mark Windschitl
Publisher: Harvard Education Press
Total Pages: 455
Release: 2020-08-05
Genre: Education
ISBN: 1682531643

2018 Outstanding Academic Title, Choice Ambitious Science Teaching outlines a powerful framework for science teaching to ensure that instruction is rigorous and equitable for students from all backgrounds. The practices presented in the book are being used in schools and districts that seek to improve science teaching at scale, and a wide range of science subjects and grade levels are represented. The book is organized around four sets of core teaching practices: planning for engagement with big ideas; eliciting student thinking; supporting changes in students’ thinking; and drawing together evidence-based explanations. Discussion of each practice includes tools and routines that teachers can use to support students’ participation, transcripts of actual student-teacher dialogue and descriptions of teachers’ thinking as it unfolds, and examples of student work. The book also provides explicit guidance for “opportunity to learn” strategies that can help scaffold the participation of diverse students. Since the success of these practices depends so heavily on discourse among students, Ambitious Science Teaching includes chapters on productive classroom talk. Science-specific skills such as modeling and scientific argument are also covered. Drawing on the emerging research on core teaching practices and their extensive work with preservice and in-service teachers, Ambitious Science Teaching presents a coherent and aligned set of resources for educators striving to meet the considerable challenges that have been set for them.

The Eye

The Eye
Author: John V. Forrester
Publisher: Elsevier Health Sciences
Total Pages: 660
Release: 2015-06-01
Genre: Medical
ISBN: 0702055549

The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. For the first time, this (print) edition also now comes with bonus access to the complete, fully searchable electronic text - including carefully selected additional information and new video content to further explain and expand on key concepts - making The Eye a more flexible, comprehensive and engaging learning package than ever before. The only all-embracing textbook of basic science suitable for trainee ophthalmologists, optometrists and vision scientists - other books concentrate on the individual areas such as anatomy. Attractive page design with clear, colour diagrams and text boxes make this a much more accessible book to learn from than many postgraduate textbooks. Presents in a readable form an account of all the basic sciences necessary for an understanding of the eye - anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology. More on molecular pathology. Thorough updating of the sections on pathology, immunology, pharmacology and immunology. Revision of all other chapters. More colour illustrations Comes with complete electronic version

Research and Networks for Decision Support in the NOAA Sectoral Applications Research Program

Research and Networks for Decision Support in the NOAA Sectoral Applications Research Program
Author: National Research Council
Publisher: National Academies Press
Total Pages: 98
Release: 2007-11-02
Genre: Science
ISBN: 0309179688

This study recommends a definition of "decision support" that emphasizes communication rather than translation and a strategy by which the small NOAA Sectoral Applications Research program can advance decision support. The book emphasizes that seasonal climate forecasts provide fundamentally new kinds of information and that integrating this information into real-world decisions will require social innovations that are not easily accomplished. It recommends that the program invest in (a) research to identify and foster the innovations needed to make information about climate variability and change more usable in specific sectors, including research on the processes that influence success or failure in the creation of knowledge-action networks for making climate information; (b) workshops to identify, catalyze, and assess the potential of knowledge-action networks in particular resource areas or decision domains; and (c) pilot projects to create or enhance these networks for supporting decisions in climate-affected sectors. It recommends that evaluation of the program be addressed with a monitoring approach.