The Applied Genomic Epidemiology Handbook
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Author | : Allison Black |
Publisher | : CRC Press |
Total Pages | : 165 |
Release | : 2024-03-18 |
Genre | : Computers |
ISBN | : 100385382X |
The Applied Genomic Epidemiology Handbook: A Practical Guide to Leveraging Pathogen Genomic Data in Public Health provides rationale, theory, and implementation guidance to help public health practitioners incorporate pathogen genomic data analysis into their investigations. During the SARS-CoV-2 pandemic, viral whole genome sequences were generated, analyzed, and shared at an unprecedented scale. This wealth of data posed both tremendous opportunities and challenges; the data could be used to support varied parts of the public health response but could be hard for much of the public health workforce to analyze and interpret, given a historical lack of experience working with pathogen genomic data. This book addresses that gap. Structured into eight wide-ranging chapters, this book describes how the overlapping timescales of pathogen evolution and infection transmission enable exploration of epidemiologic dynamics from pathogen sequence data. Different approaches to sampling and genomic data inclusion are presented for different types of epidemiologic investigations. To support epidemiologists in diving into pathogen genomic data analysis, this book also introduces the analytic tools and approaches that are readily used in public health departments and presents case studies to show step-by-step how genomic data are used and evaluated in disease investigations. Despite the breadth of scientific literature that uses pathogen genomic data to investigate disease dynamics, there remains little practical guidance to help applied epidemiologists build their ability to explore epidemiologic questions with pathogen genomic data. This handbook was written to serve as that guide. Including case studies, common methods, and software tools, this book will be of great interest to public health microbiologists or lab directors, bioinformaticians, epidemiologists, health officers, academics, as well as students working in a public health context.
Author | : Allison Black |
Publisher | : Chapman & Hall/CRC Computational Biology Series |
Total Pages | : 0 |
Release | : 2024-03-15 |
Genre | : Computers |
ISBN | : 9781032530291 |
The Applied Genomic Epidemiology Handbook: A Practical Guide to Leveraging Pathogen Genomic Data in Public Health provides rationale, theory, and implementation guidance to help public health practitioners incorporate pathogen genomic data analysis into their investigations. During the SARS-CoV-2 pandemic, viral whole genome sequences were generated, analyzed, and shared at an unprecedented scale. This wealth of data posed both tremendous opportunities and challenges; the data could be used to support varied parts of the public health response but could be hard for much of the public health workforce to analyze and interpret, given a historical lack of experience working with pathogen genomic data. This book addresses that gap. Structured into eight wide-ranging chapters, this book describes how the overlapping timescales of pathogen evolution and infection transmission enable exploration of epidemiologic dynamics from pathogen sequence data. Different approaches to sampling and genomic data inclusion are presented for different types of epidemiologic investigations. To support epidemiologists in diving into pathogen genomic data analysis, this book also introduces the analytic tools and approaches that are readily used in public health departments and presents case studies to show step-by-step how genomic data are used and evaluated in disease investigations. Despite the breadth of scientific literature that uses pathogen genomic data to investigate disease dynamics, there remains little practical guidance to help applied epidemiologists build their ability to explore epidemiologic questions with pathogen genomic data. This handbook was written to serve as that guide. Including case studies, common methods, and software tools, this book will be of great interest to public health microbiologists or lab directors, bioinformaticians, epidemiologists, health officers, academics, as well as students working in a public health context.
Author | : Mrutyunjaya Panda |
Publisher | : CRC Press |
Total Pages | : 292 |
Release | : 2024-07-15 |
Genre | : Computers |
ISBN | : 1040085628 |
With the advent of computational intelligence-based approaches, such as bio-inspired techniques, and the availability of clinical data from various complex experiments, medical consultants, researchers, neurologists, and oncologists, there is huge scope for CI-based applications in medical oncology and neurological disorders. This book focuses on interdisciplinary research in this field, bringing together medical practitioners dealing with neurological disorders and medical oncology along with CI investigators. The book collects high-quality original contributions, containing the latest developments or applications of practical use and value, presenting interdisciplinary research and review articles in the field of intelligent systems for computational oncology and neurological disorders. Drawing from work across computer science, physics, mathematics, medical science, psychology, cognitive science, oncology, and neurobiology among others, it combines theoretical, applied, computational, experimental, and clinical research. It will be of great interest to any neurology or oncology researchers focused on computational approaches.
Author | : David J. Balding |
Publisher | : John Wiley & Sons |
Total Pages | : 1219 |
Release | : 2019-07-02 |
Genre | : Science |
ISBN | : 1119429226 |
A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.
Author | : Charles Guest |
Publisher | : OUP Oxford |
Total Pages | : 467 |
Release | : 2013-02-28 |
Genre | : Medical |
ISBN | : 0191653284 |
Fully revised and updated for the third edition, the Oxford Handbook of Public Health Practice remains the first resort for all those working in this broad field. Structured to assist with practical tasks, translating evidence into policy, and providing concise summaries and real-world issues from across the globe, this literally provides a world of experience at your fingertips. Easy-to-use, concise and practical, it is structured into seven parts that focus on the vital areas of assessment, data and information, direct action, policy, health-care systems, personal effectiveness and organisational development. Reflecting recent advances, the most promising developments in practical public health are presented, as well as maintaining essential summaries of core disciplines. This handbook is designed to assist students and practitioners around the world, for improved management of disasters, epidemics, health behaviour, acute and chronic disease prevention, community and government action, environmental health, vulnerable populations, and more.
Author | : David Pencheon |
Publisher | : |
Total Pages | : 727 |
Release | : 2006 |
Genre | : Health promotion |
ISBN | : 0198566557 |
This is a practical public health book - written by public health practitioners for public health practitioners. It introduces learning practitioners to the early phases of approaching a public health issue, details why an issue is important and exactly how it can be analysed and addressed.It deals not only with the technical issues, but crucially with how those technical issues can be implemented in order to improve the health of the population directly, or via one of many important causal pathways (quality of health care design and delivery). It is written by experienced,internationally known practitioners of public health.
Author | : Lorrence H Green |
Publisher | : CRC Press |
Total Pages | : 976 |
Release | : 2021-05-04 |
Genre | : Science |
ISBN | : 1000245012 |
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise knowledge and practical information about working with microorganisms. Useful to anyone interested in microbes, the book is intended to especially benefit four groups: trained microbiologists working within one specific area of microbiology; people with training in other disciplines, and use microorganisms as a tool or "chemical reagent"; business people evaluating investments in microbiology focused companies; and an emerging group, people in occupations and trades that might have limited training in microbiology, but who require specific practical information. Key Features Provides a comprehensive compendium of basic information on microorganisms—from classical microbiology to genomics. Includes coverage of disease-causing bacteria, bacterial viruses (phage), and the use of phage for treating diseases, and added coverage of extremophiles. Features comprehensive coverage of antimicrobial agents, including chapters on anti-fungals and anti-virals. Covers the Microbiome, gene editing with CRISPR, Parasites, Fungi, and Animal Viruses. Adds numerous chapters especially intended for professionals such as healthcare and industrial professionals, environmental scientists and ecologists, teachers, and businesspeople. Includes comprehensive survey table of Clinical, Commercial, and Research-Model bacteria. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license. Chapter 21, "Archaea," of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license available at http://www.taylorfrancis.com See Emanuel Goldman's Open Access article: "Lamarck redux and other false arguments against SARS-CoV-2 vaccination," https://www.embopress.org/doi/full/10.15252/embr.202254675
Author | : Joseph Baker |
Publisher | : Routledge |
Total Pages | : 672 |
Release | : 2015-03-24 |
Genre | : Sports & Recreation |
ISBN | : 1317691172 |
Understanding and developing expertise is an important concern for any researcher or practitioner working in elite or high performance sport. Whether it's identifying talented young athletes or developing methods for integrating cutting-edge sport science into daily coaching practice, scientists, coaches and researchers all need to understand the skills, characteristics, and knowledge that distinguish the expert performer in sport. The Routledge Handbook of Sport Expertise is the first book to offer a comprehensive overview of current research and practice in the emerging field of sports expertise. Adopting a multi-disciplinary, multi-faceted approach, the book offers in-depth discussion of methodological and philosophical issues in sport expertise, as well as the characteristics that describe sporting ‘experts’ and how they can be facilitated and developed. Exploring research, theory and practice, the book also examines how scientists and practitioners can work together to improve the delivery of applied sport science. With contributions from many of the world’s leading researchers in expertise and skill acquisition in sport, the Routledge Handbook of Sport Expertise is important reading for any advanced student, researcher, coach or sport science support officer looking to better understand this cutting-edge topic.
Author | : Giuseppe La Torre |
Publisher | : SEEd |
Total Pages | : 400 |
Release | : 2010-11-25 |
Genre | : Medical |
ISBN | : 8889688564 |
This book provides not only the theory of biostatistics, but also the opportunity of applying it in practice. In fact, each chapter presents one or more specific examples on how to perform an epidemiological or statistical data analysis and includes download access to the software and databases, giving the reader the possibility of replicating the analyses described.
Author | : Shili Lin |
Publisher | : Springer Science & Business Media |
Total Pages | : 340 |
Release | : 2009-10-13 |
Genre | : Medical |
ISBN | : 3540692649 |
This handbook offers guidance on selections of appropriate computational methods and software packages for specific genetic problems. Coverage strikes a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches.