Saving Lives, Buying Time

Saving Lives, Buying Time
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 384
Release: 2004-09-09
Genre: Medical
ISBN: 0309165938

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

The Tomorrow of Malaria

The Tomorrow of Malaria
Author: Socrates Litsios
Publisher:
Total Pages: 186
Release: 2014-12-24
Genre:
ISBN: 9782940543168

A short history of malaria control and eradication. Robert Desowitz advised all malaria graduate students and their mentors to read it; Mary Galinski recommended this book to anyone working in the area of malaria research or control. Important lessons for those engaged in malaria elimination and mosquito control.

Mosquitoes of the World

Mosquitoes of the World
Author: Richard C. Wilkerson
Publisher: Johns Hopkins University Press
Total Pages: 1332
Release: 2021-01-19
Genre: Science
ISBN: 1421438143

The most complete reference work on mosquitoes ever produced, Mosquitoes of the World is an unmatched resource for entomologists, public health professionals, epidemiologists, and reference libraries.

Indian Anophelines

Indian Anophelines
Author: B. N. Nagpal
Publisher:
Total Pages: 434
Release: 1995
Genre: Anopheles
ISBN:

Indian Anophelines is the first book of its kind on the fauna of anopheline mosquitoes from India. The following aspects of mosquito systematics, biology and distribution are described: Worldwide distribution of anophelines in 12 malaria epidemiological zones, Reported distribution of anophelines in India; Bio-ecology and behaviour of mosquitoes; Updated vector status; Pictorial keys; Bibliography; and Glossary. Indian Anophelines assume special importance because of the deteriorating malaria situation in India, complicated by vector resistance to insecticides, ecological succession of mosquitoes, invasion of mosquitoes to new areas, as also their disappearance from certain areas. As a result mosquito fauna has undergone major changes and this precise knowledge at the local level in endemic regions is invariably lacking. Often the identification is made difficult due to variations in many appendages. For each anopheline species the book provides names, derivatives, type form availability, resting habits, breeding ecology, biting time, flight range, susceptibility to insecticides, relation to disease, reported distribution in India and the world, and results of vector incrimination studies. Using this book it is easy to identify specimens correctly up to species level. Taxonomic description of each species is supported by high quality illustrations giving distinguishing features of each species and their variations. The style of presentation is lucid and simple. This book is intended as a reference material for students of mosquito systematics. The book therefore would be a valuable addition in the libraries and a source of knowledge for the students engaged in research and those interested in the study of the bioecology and control of mosquitoes.

Genetic Control of Malaria and Dengue

Genetic Control of Malaria and Dengue
Author: Zach N. Adelman
Publisher: Academic Press
Total Pages: 487
Release: 2015-10-15
Genre: Medical
ISBN: 0128004053

Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

The Molecular Biology of Insect Disease Vectors

The Molecular Biology of Insect Disease Vectors
Author: J.M. Crampton
Publisher: Springer Science & Business Media
Total Pages: 590
Release: 2012-12-06
Genre: Science
ISBN: 9400915357

Only one generation ago, entomology was a proudly isolated discipline. In Comstock Hall, the building of the Department of Entomology at Cornell University where I was first introduced to experimental science in the laboratory of Tom Eisner, those of us interested in the chemistry of life felt like interlopers. In the 35 years that have elapsed since then, all of biology has changed, and entomology with it. Arrogant molecular biologists and resentful classical biologists might think that what has happened is a hostile take-over of biology by molecular biology. But they are wrong. More and more we now understand that the events were happier and much more exciting, amounting to a new synthesis. Molecular Biology, which was initially focused on the simplest of organisms, bacteria and viruses, broke out of its confines after the initial fundamental questions were answered - the structure of DNA, the genetic code, the nature of regulatory genes - and, importantly, as its methods became more and more generally applicable. The recombinant DNA revo lution of the 1970s, the development of techniques for sequencing macromolecules, the polymerase chain reaction, new molecular methods of genetic analysis, all brought molecular biology face to face with the infinite complexity and the exuber ant diversity of life. Molecular biology itself stopped being an isolated diScipline, pre occupied with the universal laws of life, and became an approach to addressing fas cinating specific problems from every field of biology.

Taxonomists' Glossary of Mosquito Anatomy

Taxonomists' Glossary of Mosquito Anatomy
Author: Ralph E. Harbach
Publisher: Plexus Publishing (NJ)
Total Pages: 440
Release: 1980
Genre: Science
ISBN:

Anatomical and descriptive terminology of mosquitoes listed under separate sections on adult, egg, larva, pupa, and vestiture. Each entry gives recommended abbreviation, illustrative figures in this publication, original reference, definitions, synonyms, and supplementary information. Bibliography. Index.

The Mosquito

The Mosquito
Author: Timothy C. Winegard
Publisher: Penguin
Total Pages: 639
Release: 2019-08-06
Genre: History
ISBN: 1524743437

**The instant New York Times bestseller.** *An international bestseller.* Finalist for the Lane Anderson Award Finalist for the RBC Taylor Award “Hugely impressive, a major work.”—NPR A pioneering and groundbreaking work of narrative nonfiction that offers a dramatic new perspective on the history of humankind, showing how through millennia, the mosquito has been the single most powerful force in determining humanity’s fate Why was gin and tonic the cocktail of choice for British colonists in India and Africa? What does Starbucks have to thank for its global domination? What has protected the lives of popes for millennia? Why did Scotland surrender its sovereignty to England? What was George Washington's secret weapon during the American Revolution? The answer to all these questions, and many more, is the mosquito. Across our planet since the dawn of humankind, this nefarious pest, roughly the size and weight of a grape seed, has been at the frontlines of history as the grim reaper, the harvester of human populations, and the ultimate agent of historical change. As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power. The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village. Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable. Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito’s reign through human history and her indelible impact on our modern world order.