Thalassaemia: The Biography

Thalassaemia: The Biography
Author: David Weatherall
Publisher: Oxford University Press
Total Pages: 258
Release: 2010-08-26
Genre: Language Arts & Disciplines
ISBN: 0199565600

Here is a complete history of Thalassaemia, the most common type of genetic disorder in the human population, and one of the first whose genetic basis was established. Treatment is also discussed as well at an assessment of how molecular approaches are impacting medicine. - Publisher.--

The Thalassaemia Syndromes

The Thalassaemia Syndromes
Author: David J. Weatherall
Publisher: John Wiley & Sons
Total Pages: 864
Release: 2008-04-30
Genre: Medical
ISBN: 0470695943

In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.

Prevention of Thalassaemias and Other Haemoglobin Disorders

Prevention of Thalassaemias and Other Haemoglobin Disorders
Author: Galanello Renzo
Publisher:
Total Pages: 190
Release: 2003
Genre:
ISBN: 9789963623396

Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.

Cholera: The Biography

Cholera: The Biography
Author: Christopher Hamlin
Publisher: Oxford University Press, USA
Total Pages: 355
Release: 2009-10-08
Genre: Medical
ISBN: 019954624X

Cholera is a dangerous and frightening disease that can kill within hours. Chris Hamlin not only tells how the bacterial cause of cholera was discovered, but describes the experience of different countries, some of which continue to struggle with the disease today. Cholera is part of the Oxford series, Biographies of Diseases.

Iron Boy

Iron Boy
Author: Arthur Bozikas
Publisher: Next Chapter
Total Pages: 297
Release: 2022-02-16
Genre: Biography & Autobiography
ISBN:

If you ask people about their earliest memories, most will recall holidays and family parties. But for Arthur, many of his earliest memories include going with his parents to regular hospital visits and staying overnight for blood transfusions. These treatments have been a frequent part of his life since birth because he has beta-thalassemia major: a rare genetic disorder that reduces his body's ability to produce enough healthy red blood cells. When reaching adolescence, most teenagers want more freedom, independence and control in their lives. For Arthur, it was the opposite, as he discovered that his lifespan would only last up to adulthood. After becoming an adult, Arthur was waiting for his death. It was at the eleventh hour, at the age of twenty-one, when Arthur was introduced to a miracle treatment, but only after the damage of iron overload from all the blood transfusion was done to his body. Grateful to be given a chance to survive for a few more years, Arthur decided to do something with his life; to get married, buy a house and also to have children, knowing he had no prospect of any future for himself.

Disorders of Hemoglobin

Disorders of Hemoglobin
Author: Martin H. Steinberg
Publisher: Cambridge University Press
Total Pages: 883
Release: 2009-08-17
Genre: Medical
ISBN: 0521875196

Completely revised new edition of the definitive reference on disorders of hemoglobin.

Haemoglobinopathy Diagnosis

Haemoglobinopathy Diagnosis
Author: Barbara J. Bain
Publisher: John Wiley & Sons
Total Pages: 452
Release: 2020-02-28
Genre: Medical
ISBN: 1119579996

An updated, essential guide for the laboratory diagnosis of haemoglobin disorders This revised and updated third edition of Haemoglobinopathy Diagnosis offers a comprehensive review of the practical information needed for an understanding of the laboratory diagnosis of haemoglobin disorders. Written in a concise and approachable format, the book includes an overview of clinical and laboratory features of these disorders. The author focuses on the selection, performance, and interpretation of the tests that are offered by the majority of diagnostic laboratories. The book also explains when more specialist tests are required and explores what specialist referral centres will accomplish. The information on diagnosis is set in a clinical context. The third edition is written by a leading haematologist with a reputation for educational excellence. Designed as a practical resource, the book is filled with illustrative examples and helpful questions that can aide in the retention of the material presented. Additionally, the author includes information on the most recent advances in the field. This important text: • Contains a practical, highly illustrated, approach to the laboratory diagnosis of haemoglobin disorders • Includes “test-yourself” questions and provides an indispensable tool for learning and teaching • Presents new material on antenatal screening/prenatal diagnostic services • Offers myriad self-assessment case studies that are ideal for the trainee Written for trainees and residents in haematology, practicing haematologists, and laboratory scientists, Haemoglobinopathy Diagnosis is an essential reference and learning tool that provides a clear basis for understanding the diagnosis of haemoglobin disorders.

Iron Chelation Therapy

Iron Chelation Therapy
Author: Chaim Hershko
Publisher: Taylor & Francis US
Total Pages: 290
Release: 2002
Genre: Medical
ISBN: 9780306467851

Within the last few years, iron research has yielded exciting new insights into the understanding of normal iron homeostasis. Such development, and the evolution of improved strategies of Iron Chelating Therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant developments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload. This volume highlights the impact of long term Iron Celating Therapy using deferoxamine or the new, but controversial oral iron chelator deferiprone based on experience gained by multicenter trails, with special emphasis on survival, morbidity and drug toxicity; it reviews the development of the new and improved orally effective chelators suitable for clinical use in the near future and examines novel strategies of iron chelating treatment for the control of cell proliferation in malignant disease or malaria.

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 804
Release: 2002-07-19
Genre: Medical
ISBN: 9780309072793

This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.