Textbook of Organic Medicinal and Pharmaceutical Chemistry
Author | : Charles Owens Wilson |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 1150 |
Release | : 1977 |
Genre | : Medical |
ISBN | : |
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Author | : Charles Owens Wilson |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 1150 |
Release | : 1977 |
Genre | : Medical |
ISBN | : |
Author | : Avianna Stokes |
Publisher | : |
Total Pages | : 222 |
Release | : 2019-06-25 |
Genre | : |
ISBN | : 9781632415356 |
Medicinal chemistry and pharmacology are closely associated fields. They are concerned with the design and synthesis of drugs for the pharmaceutical industry. These drugs are generally organic compounds and can be divided into classes of biologics and small organic compounds. Medicinal chemistry is focused on the production of small organic molecules such as atorvastatin, fluticasone, clopidogrel, etc. The principles of synthetic organic chemistry, computational chemistry, enzymology, structural biology and chemical biology are integrated in medicinal chemistry. The study of drugs and their effects on the living body are explored in pharmacology. It involves the research, discovery and characterization of the chemicals that exhibit a biological effect. All therapies that are designed to target diseases, defects and pathogens and also advance preventive care, diagnostics and personalized medicine are a result of tremendous research in pharmacology. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the fields of medicinal chemistry and pharmacology. The various advancements in these fields are glanced at and their applications as well as ramifications are looked at in detail. This book is a vital tool for all researching and studying pharmaceutical science and medicinal chemistry.
Author | : David G. Watson |
Publisher | : Elsevier Health Sciences |
Total Pages | : 480 |
Release | : 2015-12-24 |
Genre | : Medical |
ISBN | : 0702069884 |
Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on Biotech products. New chapter on electrochemical methods in diagnostics. Greatly extended chapter on molecular emission spectroscopy to accommodate developments and innovations in the area. Now on StudentConsult
Author | : Marc Harrold |
Publisher | : ASHP |
Total Pages | : 405 |
Release | : 2013-01-18 |
Genre | : Medical |
ISBN | : 1585283649 |
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author | : Katja A. Strohfeldt |
Publisher | : John Wiley & Sons |
Total Pages | : 290 |
Release | : 2015-02-16 |
Genre | : Science |
ISBN | : 0470665580 |
A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.
Author | : Donald Cairns |
Publisher | : Pharmaceutical Press |
Total Pages | : 321 |
Release | : 2012 |
Genre | : Medical |
ISBN | : 0853699798 |
An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems
Author | : Christine Bladon |
Publisher | : John Wiley & Sons |
Total Pages | : 240 |
Release | : 2002-04-03 |
Genre | : Science |
ISBN | : 9780471496373 |
Providing a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used therapeutically. With help of numerous illustrations, it covers both the compounds and how therapeutics exert their influence throuhg an understanding of biological processes. * Includes the latest developments in the field * Covers the various strategies behind the development and production of a range of key clinically useful compounds * Focuses on the concepts and ideas of why compounds are developed as pharmaceuticals * Provides many examples and problems Invaluable to all students of chemistry, medicinal and pharmaceutical chemistry, pharmacy and pharmacology. Will also be of interest to researchers and professionals needing a concise, up-to-date account of this subject.
Author | : J. S. Qadry |
Publisher | : |
Total Pages | : 286 |
Release | : 2012 |
Genre | : |
ISBN | : 9788123919195 |
Textbook of Inorganic Pharmaceutical and Medicinal Chemistry in its 11th edition has been meticulously revised in a way that highlights the importance of the role of pharmacy education controlling authorities in India devising study materials that would give them parity with all the courses including the newly introduced Pharm. D. course. The individual chapters are based on my well-known original uniformly designed principles of monographs - like presentation, keeping together drugs' groups with similar therapeutic activities. Actions of drugs on the organism as also actions of organism on the drug (e.g. biotransformation) are - to the extent chemical contemplation is accessible - part of the biochemically oriented pharmaceutical chemistry. The regularly recurring sections of the book refer particularly to structure of drugs, preparation/synthesis, properties, pharmacology, biotransformation, purity tests, analysis, uses, etc. The book is meant for students of all courses in pharmacy and for the interested chemists and medical students. It will further serve the practising hospital pharmacists for continuing education and as a reference book for working pharmacists including those connected with the industry especially the ones engaged in analytical work.
Author | : Camille Georges Wermuth |
Publisher | : Elsevier |
Total Pages | : 903 |
Release | : 2015-07-01 |
Genre | : Science |
ISBN | : 012417213X |
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com
Author | : Ali Mohammed |
Publisher | : Oxford and Ibh Publishers |
Total Pages | : 314 |
Release | : 2018-01-30 |
Genre | : Pharmaceutical chemistry |
ISBN | : 9788123904153 |
The book is intended for use by undergraduate students of pharmacy . It follows the general arrangement and classification of drugs. The general format of presentation of each compound includes introduction preparation physical characters. Chemical properties identification tests purity tests assay methods and uses.