T Type Calcium Channels In Basic And Clinical Science
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| Author | : Stephen W. Schaffer |
| Publisher | : Springer |
| Total Pages | : 158 |
| Release | : 2014-11-26 |
| Genre | : Science |
| ISBN | : 3709114136 |
T-type calcium channels are prevalent in every organ of the body, and are believed to play a part in a variety of physiological processes, including contraction, shape change, secretion, endo- and exocytosis, cell proliferation and differentiation, modulation of enzyme function, and cell cycle progression. As such, research on the roles of these channels in a wide range of diseases has attracted increasing attention in recent years. The purpose of this book is to present a series of unique and comprehensive reviews of our current understanding of T-type calcium channels at the level of the basic sciences as well as the clinical sciences. For key organ systems, information is provided on the correlation between the molecular, biophysical and pharmacological properties of the channels, their cellular mechanisms, and their potential roles in the pathogenesis of various diseases. The compilation presents both commonplace and less well-known findings on these channels in a format designed to appeal to both casual readers and specialists in basic and clinical research on these transporters.
| Author | : Gerald W. Zamponi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 402 |
| Release | : 2005-02-10 |
| Genre | : Medical |
| ISBN | : 9780306478406 |
Voltage Gated Calcium Channels is the first comprehensive book in the calcium channel field, encompassing over thirty years of progress towards our understanding of calcium channel structure, function, regulation, physiology, pharmacology, and genetics. This book balances contributions from many of the leading authorities in the calcium channel field with fresh perspectives from risings stars in the area, taking into account the most recent literature and concepts. This is the only all-encompassing calcium channel book currently available, and is an essential resource for academic researchers at all levels in the areas neuroscience, biophysics, and cardiovascular sciences, as well as to researchers in the drug discovery area.
| Author | : Richard W. Tsien |
| Publisher | : |
| Total Pages | : 420 |
| Release | : 1998 |
| Genre | : Calcium |
| ISBN | : |
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 307 |
| Release | : 2013-07-24 |
| Genre | : Science |
| ISBN | : 0124079385 |
Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
| Author | : Juliusz Ashot Kozak |
| Publisher | : CRC Press |
| Total Pages | : 343 |
| Release | : 2017-07-14 |
| Genre | : Science |
| ISBN | : 149875273X |
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
| Author | : Fatima Shad Kaneez |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 204 |
| Release | : 2018-10-10 |
| Genre | : Science |
| ISBN | : 1789842271 |
Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.
| Author | : Constance Hammond |
| Publisher | : Elsevier |
| Total Pages | : 602 |
| Release | : 2024-05-30 |
| Genre | : Psychology |
| ISBN | : 0323986137 |
Unveiling the latest research in neurophysiology, Cellular and Molecular Neurophysiology, Fifth Edition continues to stand as the only resource in the field. This book remains the standard for those who seek to explore the intricate molecular and cellular physiology of neurons and synapses. Notably, this new edition delves even deeper into the molecular properties and functions of excitable cells, offering unparalleled insights. In this edition, there are two groundbreaking chapters. The first reviews metabotropic receptors for olfactory transduction, while the second presents cutting-edge techniques for neuroscience research. Hypothesis-driven rather than a dry presentation of facts, the content firmly based on numerous experiments performed by top experts in the field, teaches students how to build and conduct intelligent research experiments. This book promotes a true understanding of nerve cell function and will be a useful resource for practicing neurophysiologists, neurobiologists, neurologists, and students in a graduate-level course on the topic alike. - Authoritative foundational coverage of basic cellular and molecular neurophysiology - Includes new chapters on metabotropic olfactory receptors for sensory transduction and experimental techniques used by neurophysiologists
| Author | : Avital Schurr |
| Publisher | : CRC Press |
| Total Pages | : 355 |
| Release | : 2020-02-06 |
| Genre | : Medical |
| ISBN | : 1000714357 |
Brain Slices in Basic and Clinical Research describes advancements in the field of brain function and dysfunction through use of central nervous system slice preparations. Topics are authored by leading scientists and include the following: Mechanisms of synaptic plasticity as the basis of memory processes Chaos and synaptic variability Brain calcium currents Glutamate receptors Pathophysiology of excitotoxins Cerebral hypoxia-ischemia Neuronal injury Free radicals Optical methods of measuring brain metabolism Voltammetry in brain slices Calcium imaging Patch-clamp recording and application of macromolecules through patch-clamp pipettes in brain slices Intracellular double labeling of various neuronal populations Use of brain slices in teaching neurophysiological methods Most of the topics are published in book format for the first time, and some of the techniques are more fully detailed than in any other book.
| Author | : Ihor Gussak |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 982 |
| Release | : 2008-09-08 |
| Genre | : Medical |
| ISBN | : 1846288541 |
This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 42 |
| Release | : 2012-12-26 |
| Genre | : Science |
| ISBN | : 148162170X |
Calcium Channels—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Calcium Channels in a concise format. The editors have built Calcium Channels—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Calcium Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Calcium Channels—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
