Synthesis And Biological Evaluation Of 15 Diphenylpyrrole Derivatives As Cox 2 Selective Inhibitors And No Releasing Agents And Development Of A Novel Brd9 Chemical Probe
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| Author | : Sara Consalvi |
| Publisher | : Sapienza Università Editrice |
| Total Pages | : 130 |
| Release | : 2020-06-30 |
| Genre | : Science |
| ISBN | : 8893771373 |
This PhD thesis consists of three projects: the first and the second ones, carried out at Sapienza University of Rome, deal with the design and synthesis of novel COX-2 selective inhibitors and dual COX-2 inhibitors/NO-releasing agents, respectively. The third project concerns the development of a novel BRD9 chemical probe and was realized at the University of Oxford (Department of Chemistry).
| Author | : Davide Comite |
| Publisher | : Sapienza Università Editrice |
| Total Pages | : 349 |
| Release | : 2020-06-30 |
| Genre | : Computers |
| ISBN | : 889377142X |
This volume collects the main results of the Author’s Ph.D. course in Electromagnetics and Mathematical Models for Engineering, attended at ‘Sapienza’ University of Rome from November 2011 to February 2015, in the Electromagnetic Fields 1 Lab of the Department of Information Engineering, Electronics and Telecommunications, under the tutoring of Prof. Alessandro Galli.
| Author | : Angelo Gaetani |
| Publisher | : Sapienza Università Editrice |
| Total Pages | : 202 |
| Release | : 2020-06-30 |
| Genre | : Architecture |
| ISBN | : 8893771446 |
Considering the seismic behaviour of cultural heritage buildings, recent earthquakes have emphasised the high vulnerability of vaulted structures. In this regard, the present thesis deals with masonry cross vaults, among the most diffused and fascinating structural typologies of the European cultural heritage. After a thorough review of cross vault historical developments, the focus is shifted to the shaking table tests of a scaled arch. These two points provided valuable information to calibrate the finite element model of cross vault, discussed next. Finally, the influence of the main geometrical and mechanical parameters on the seismic capacity of cross vaults are examined by means of a sensitivity analysis.
| Author | : L.R. Watkins |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 248 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9783764358495 |
The purpose of this book is to examine immune-to-brain communication from the viewpoint of its effect on pain processing, and to clarify the major role that substances released by immune cells play in pain modulation. In these chapters, contributed by major laboratories whose focus is understanding how cytokines modulate pain, the perspectives examined range from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans. -- book cover.
| Author | : Jun Kimura |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 989 |
| Release | : 2006-06-08 |
| Genre | : Medical |
| ISBN | : 0444513582 |
A volume in the Handbook of Clinical Neurophysiology series on peripheral neuropathies. The ultimate reference source for clinical neurophysiologists on peripheral neuropathies. Volume in a prestigious series published in association with the International Federation of Clinical Neurophysiology. International contributor list drawn from around the world.
| Author | : Pedro Navascués Palacio |
| Publisher | : |
| Total Pages | : 347 |
| Release | : 2004-01-01 |
| Genre | : Cathedrals |
| ISBN | : 9788497851084 |
