The challenges associated with the struggles for attainment of the Sustainable Development Goals (SDGs) and objectives are as diverse and complex as the variety of human societies, national conditions and natural ecosystems worldwide. Despite decades of economic growth and technological advances, our world is plagued by poverty, hunger, disease, conflicts and inequality, and many societies are under the strain of environmental changes and governance failure. Such global-scale challenges call for the SDGs to be translated beyond bold concepts and aspirational targets into concrete programs and feasible plans that are substantively valuable, locally acceptable, pragmatic and operationally implementable. In the pursuit of the SDGs, positive results are far from guaranteed. Success is uncertain. Instead, the path forward requires difficult learning, experimentation and adaptation by multiple stakeholders. Loss and sacrifice are foreseeable and often inevitable. This important book captures the lessons from ongoing struggles and the early successes. Productive failures and emerging practices are identified, analyzed and promulgated for interdisciplinary learning by, and for the inspiration of, like-minded individuals, organizations, communities and nations worldwide. They can also inform and enrich the curricula in universities, training institutions and schools to prepare future generations of citizens, leaders and activists with the ethos and values of sustainability and social responsibility. The book offers a platform for academics, practitioners and concerned global citizens to identify pathways forward on the immense challenges of sustainability.