Superoxide Dismutase Sod
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| Author | : Giuseppe Valacchi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 324 |
| Release | : 2008-06-06 |
| Genre | : Medical |
| ISBN | : 1402083998 |
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
| Author | : Dirk Inze |
| Publisher | : CRC Press |
| Total Pages | : 417 |
| Release | : 2001-10-18 |
| Genre | : Science |
| ISBN | : 0203303148 |
Plants depend on physiological mechanisms to combat adverse environmental conditions, such as pathogen attack, wounding, drought, cold, freezing, salt, UV, intense light, heavy metals and SO2. Many of these cause excess production of active oxygen species in plant cells. Plants have evolved complex defense systems against such oxidative stress. The
| Author | : Kelong Fan |
| Publisher | : Frontiers Media SA |
| Total Pages | : 151 |
| Release | : 2021-05-31 |
| Genre | : Science |
| ISBN | : 2889668215 |
| Author | : Nancy H. Phillips |
| Publisher | : Nova Science Publishers |
| Total Pages | : 0 |
| Release | : 2016 |
| Genre | : Superoxide dismutase |
| ISBN | : 9781634854603 |
Superoxide dismutase (SOD) is an antioxidant enzyme that scavenges superoxide radicals, and are found in all living cells. SODs have been studied as a therapeutic tool for very diverse pathological situations for more than 30 years and, in many animal models and a few clinical trials, their use has shown positive outcomes. In this book, Chapter One begins with an overview of the association between manganese superoxide dismutase and cardiovascular disease. Chapter Two examines the indispensable roles of superoxide dismutation in mammalian erythrocytes. Chapter Three discusses the structure, catalysis and therapeutic uses of the Fe/Mn SOD family. Chapter Four reviews several strategies of nanomedicines development that have been used to prolong the circulation time and improve the therapeutic action of SODs. Chapter Five studies the emerging role of SOD3 in controlling skin inflammation and immune responses.
| Author | : Sudhir P. Singh |
| Publisher | : Springer Nature |
| Total Pages | : 507 |
| Release | : 2019-10-01 |
| Genre | : Science |
| ISBN | : 9811506906 |
This book discusses molecular approaches in plant as response to environmental factors, such as variations in temperature, water availability, salinity, and metal stress. The book also covers the impact of increasing global population, urbanization, and industrialization on these molecular behaviors. It covers the natural tolerance mechanism which plants adopt to cope with adverse environments, as well as the novel molecular strategies for engineering the plants in human interest. This book will be of interest to researchers working on the impact of the changing environment on plant ecology, issues of crop yield, and nutrient quantity and quality in agricultural crops. The book will be of interest to researchers as well as policy makers in the environmental and agricultural domains.
| Author | : M. Senthilkumar |
| Publisher | : |
| Total Pages | : 296 |
| Release | : 2021 |
| Genre | : Botany |
| ISBN | : 9781071610800 |
This manual details the techniques involved in the study of plant microbe interactions (PMI). Covering a wide range of basic and advanced techniques associated with research on biological nitrogen fixation, microbe-mediated plant nutrient use efficiency, the biological control of plant diseases and pests such as nematodes, it will appeal to postgraduate students, research scholars and postdoctoral fellows, as well as teachers from various fields, including pathology, entomology and agronomy. It consists of five broad sections featuring different units. Information panels at the beginning of each unit present essential knowledge as well as advances in a particular topic. The manual can also serve as a textbook for undergraduate courses like Techniques for Plant-Microbe Interactions; Biological Control of Plant Diseases; and Nutrient Use Efficiency. Providing basic insights and working protocols from all related disciplines, this unique laboratory manual is a valuable resource for researchers interested in investigating PMI.
| Author | : Sergei Magliozzi |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2018 |
| Genre | : Superoxide dismutase |
| ISBN | : 9781536130805 |
In this compilation, the authors comprehensively investigate SOD effects in the homeostasis of mammal endometrium, using available information on several species and their team experience relating to the topic. In addition, they also address its role in endometrial integrity and some uterine clinical conditions and infertility. The current knowledge of plant SODs, their abiotic-stress modulated expression and activity, and analyses results on genetic engineering of plant SODs are summarized. Significance of superoxide dismutases in the crop improvement for stress tolerance is also discussed. This book reviews the oxidative stress and damage to plants, while also summarizing the characteristics of SOD enzymes and discussing their involvement in the tolerance of plants against abiotic stress. Additionally, many authors have studied the protective role of SOD in the mice cochlea, however more recently the role of SOD gene polymorphisms in the susceptibility of sudden sensorineural hearing loss has been investigated. Therefore, the authors also examine the role of SOD in the cochlea and its involvement in the pathogenesis of noise induced hearing loss, age related hearing loss and sudden sensorineural hearing loss.
| Author | : Nancy H. Phillips |
| Publisher | : Nova Biomedical Books |
| Total Pages | : 185 |
| Release | : 2016 |
| Genre | : Medical |
| ISBN | : 9781634854818 |
Superoxide dismutase (SOD) is an antioxidant enzyme that scavenges superoxide radicals, and are found in all living cells. SODs have been studied as a therapeutic tool for very diverse pathological situations for more than 30 years and, in many animal models and a few clinical trials, their use has shown positive outcomes. In this book, Chapter One begins with an overview of the association between manganese superoxide dismutase and cardiovascular disease. Chapter Two examines the indispensable roles of superoxide dismutation in mammalian erythrocytes. Chapter Three discusses the structure, catalysis and therapeutic uses of the Fe/Mn SOD family. Chapter Four reviews several strategies of nanomedicines development that have been used to prolong the circulation time and improve the therapeutic action of SODs. Chapter Five studies the emerging role of SOD3 in controlling skin inflammation and immune responses.
| Author | : Michael Simic |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1064 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 1468455680 |
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
| Author | : Murat Şentürk |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 270 |
| Release | : 2017-03-29 |
| Genre | : Science |
| ISBN | : 9535130579 |
Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.
