Structure Function And Evolution In Proteins
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Proteins
Author | : David Whitford |
Publisher | : John Wiley & Sons |
Total Pages | : 544 |
Release | : 2013-04-25 |
Genre | : Science |
ISBN | : 1118685725 |
Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.
Sequence — Evolution — Function
Author | : Eugene V. Koonin |
Publisher | : Springer Science & Business Media |
Total Pages | : 482 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 1475737831 |
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Hemoglobin
Author | : Jay F. Storz |
Publisher | : |
Total Pages | : 258 |
Release | : 2019 |
Genre | : Medical |
ISBN | : 0198810687 |
Provides a synthesis of our current understanding of hemoglobin (Hb) function and evolution, and illustrates how research on this protein has provided more general insights into mechanisms of protein evolution and biochemical adaptation.
Introduction to Protein Science
Author | : Arthur Lesk |
Publisher | : Oxford University Press, USA |
Total Pages | : 476 |
Release | : 2010-03-25 |
Genre | : Education |
ISBN | : 0199541302 |
Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its function.
Computational Methods in Protein Evolution
Author | : Tobias Sikosek |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2018-10-09 |
Genre | : Science |
ISBN | : 9781493987351 |
This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.
Gene Sharing and Evolution
Author | : Joram Piatigorsky |
Publisher | : Harvard University Press |
Total Pages | : 434 |
Release | : 2007-02-28 |
Genre | : Science |
ISBN | : 9780674023413 |
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
Protein Engineering
Author | : Huimin Zhao |
Publisher | : John Wiley & Sons |
Total Pages | : 41 |
Release | : 2021-08-23 |
Genre | : Science |
ISBN | : 3527344705 |
A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.