Stereochemistry - Workbook

Stereochemistry - Workbook
Author: Karl-Heinz Hellwich
Publisher: Springer Science & Business Media
Total Pages: 203
Release: 2006-10-11
Genre: Science
ISBN: 3540329129

This workbook in stereochemistry is designed for students, lecturers and scientists in chemistry, pharmacy, biology and medicine who deal with chiral chemical compounds and their properties. It serves as a supplement to textbooks and seminars and thus provides selected examples for students to practice the use of the conventions and terminology for the exact three-dimensional description of chemical compounds. It contains 191 problems with extended solutions.

Introduction to Stereochemistry

Introduction to Stereochemistry
Author: Kurt Mislow
Publisher: Courier Corporation
Total Pages: 210
Release: 2012-06-11
Genre: Science
ISBN: 0486151158

Molecular shape, form, and symmetry play a central role in organic chemistry, and this text presents a brief introduction to the conceptual basis of stereochemistry. Its focus lies in the fundamentals of structural stereochemistry, rather than the dynamic aspects that are more relevant to reaction mechanisms. The three-part treatment deals with structure and symmetry, stereoisomerism, and the separation and configuration of stereoisomers. The first section reviews molecular architecture, relating empirical bonding geometries to the hybridization of the central carbon atom. Students receive a nonrigorous treatment of symmetry elements and point groups, with particular focus on the presence or absence of reflection symmetry. The second section classifies stereoisomers according to symmetry properties and to the nature of their barriers; it also discusses the dependence of optical activity on structure and concludes with an examination of topological isomerism. The third and final section explores the conceptual basis of asymmetric syntheses and kinetic resolutions. Each of the major sections features a series of exercises that reinforce and extend the preceding material, and answers are provided. Preface to the Dover edition. Answers to Exercises. Bibliography. Index.

Stereochemistry

Stereochemistry
Author: Anil V. Karnik
Publisher: Elsevier
Total Pages: 622
Release: 2021-07-21
Genre: Science
ISBN: 012821063X

Stereochemistry: A Three-Dimensional Insight draws on the knowledge of its expert authors, providing a systematic treatment on the fundamental aspects of stereochemistry, covering conformational aspects, configurational aspects, effects of bulkiness, stereoelectronic effects on properties of molecules, and the genesis of enantiomerism, among other topics. Visuals and exercises are included to consolidate the principles learned, and the contents are carefully structured to prepare readers for predicting and organizing reaction components to obtain desired stereochemical outcomes. This book is an indispensable guide for all those exploring stereochemistry within their work. The principles of stereochemistry are fundamental to understanding chemical behavior and can provide insights into a whole range of problems, from unusual selectivity and unexpected behaviors, to abnormally fast reactions and surprising biochemical preferences. However, understanding and exploring these 3D effects can be difficult within a 2D medium. This book has been designed to address this problem, providing foundational guidance on the principles and applications of stereochemistry that are fully supported by multimedia visuals. - Combines foundational concepts and definitions with examples of stereochemistry in practice - Highlights the conformational and configurational impact of atomic arrangement on chemical behavior - Outlines methods of analysis - Provides practical exercises and detailed multimedia visuals to support learning

Stereochemistry of Organic Compounds

Stereochemistry of Organic Compounds
Author: Ernest L. Eliel
Publisher: John Wiley & Sons
Total Pages: 1296
Release: 1994-09-28
Genre: Science
ISBN: 0471016705

Stereochemistry of Organic Compounds The first fully referenced, comprehensive book on this subject in more than thirty years, Stereochemistry of Organic Compounds contains up-to-date coverage and insightful exposition of all important new concepts, developments, and tools in the rapidly advancing field of stereochemistry, including: * Asymmetric and diastereoselective synthesis * Conformational analysis * Properties of enantiomers and racemates * Separation and analysis of enantiomers and diastereoisomers * Developments in spectroscopy (including NMR), chromatography, and molecular mechanics as applied to stereochemistry * Prostereoisomerism * Conceptual foundations of stereochemistry, including terminology and symmetry concepts * Chiroptical properties Written by the leading authorities in the field, the text includes more than 4,000 references, 1,000 illustrations, and a glossary of stereochemical terms.

Introduction to Stereochemistry

Introduction to Stereochemistry
Author: Andrew Clark
Publisher: Royal Society of Chemistry
Total Pages: 201
Release: 2023-01-17
Genre: Science
ISBN: 1839164131

CHEMISTRY STUDENT GUIDES. GUIDED BY STUDENTS Why did the drug thalidomide cause birth defects? What is the chemical difference between sucrose and lactose in your food? Stereochemistry holds the answer and is essential to the understanding of the chemistry of life. Stereochemistry is an important concept that often causes confusion amongst students when they learn it for the first time. Unlike most other areas of chemistry, it requires the chemist to visualise molecules in 3D, which can be difficult. In this book we deal with tricky concepts like conformation and configuration, how to represent them accurately and how to use the correct terms to describe them in both organic and inorganic chemistry. We involved students in the writing process to ensure we deal with areas that you find difficult, in an understandable language. With problems designed to focus on common errors and misconceptions, real life examples, and practical hands-on exercises coupled with visualisation tips, our intention is to give you the tools to become confident in stererochemistry. Complementing mainstream organic textbooks, or self-study, this book is for anyone who has struggled with describing alkenes as E or Z, assigning R and S absolute configurations, drawing Newman projections or chair representations of cyclohexanes, axial chirality, understanding the stereochemistry of octahedral metal complexes and indeed explaining complexities observed in NMR spectra. Chemistry Student Guides are written with current students involved at every stage, guiding the books towards the most challenging aspects of the topic. Student co-authors for Introduction to Stereochemistry are Caroline Akamune, Michael Lloyd and Matthew Taylor.

Introduction to Stereochemistry

Introduction to Stereochemistry
Author: Torsten Schmiermund
Publisher: Springer Nature
Total Pages: 56
Release: 2021-06-07
Genre: Science
ISBN: 3658320354

Conformal, diastereomers, rotamers, tautomers, anomers: The multitude of terms used in stereochemistry quickly makes this subfield of chemistry confusing. In addition, there are different nomenclatures and different forms of representation (Fischer projection, Haworth ring formula, Newman projection). This essential deals with basic static stereochemistry and gives an overview of the different isomeric forms and nomenclatures. It is thus both a help and a reference book. This Springer essential is a translation of the original German 1st edition essentials, Einführung in die Stereochemie by Torsten Schmiermund, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2019. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.

Stereochemistry and Organic Reactions

Stereochemistry and Organic Reactions
Author: Dipak Kumar Mandal
Publisher: Academic Press
Total Pages: 640
Release: 2021-04-21
Genre: Science
ISBN: 0128240938

Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects and Asymmetric Synthesis provides coverage on the stereochemistry of reactions of all mechanistic types, ranging from ionic, pericyclic and transition metal-catalyzed to radical and photochemical. Chapters cover acyclic molecules, cyclic molecules, the stereochemistry of organic reactions, the perturbation molecular orbital theory for the origin of stereoelectronic effects, and an introduction to the principles of stereoselectivity and hierarchical levels of asymmetric synthesis. Each chapter includes problems that reinforce main themes, making it valuable to students, teachers and researchers working in organic, biological and medicinal chemistry, as well as biologists, pharmacologists, polymer chemists and chemists. - Presents a holistic and unified approach to stereochemical understanding and predictions, covering reactions of all mechanistic classes - Includes two background chapters on perturbation theory and stereoselective principles, along with asymmetric designs - Features novel rules and mnemonics to delineate product stereochemistry - Includes up-to-date coverage with over 1300 selective references

Organic Stereochemistry

Organic Stereochemistry
Author: Hua-Jie Zhu
Publisher: John Wiley & Sons
Total Pages: 336
Release: 2015-08-10
Genre: Science
ISBN: 3527338225

Adopting a novel approach to the topic by combining theoretical knowledge and practical results, this book presents the most popular and useful computational and experimental methods applied for studying the stereochemistry of chemical reactions and compounds. The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the second part covers the different methodologies, such as optical rotation, electronic circular dichroism, vibrational circular dicroism, and Raman spectroscopy. The third section then goes on to describe selective examples in organic synthesis, classified by reaction type, i.e. enantioselective, chemoselective and stereoselective reactions. A final chapter on total synthesis of natural products rounds off the book. A valuable reference for researchers in academia and industry working in the field of organic synthesis, computational chemistry, spectroscopy or medicinal chemistry.

Basic Concepts in Organic Stereochemistry

Basic Concepts in Organic Stereochemistry
Author: Sunil Kumar Talapatra
Publisher: Springer Nature
Total Pages: 266
Release: 2023-01-01
Genre: Science
ISBN: 3030959902

This book discusses essential stereochemical concepts associated with organic molecules (natural or synthetic), as reflected in the course of their many reactions, their mechanisms, their asymmetric synthesis, biosynthesis, and biological activities. This treatise provides useful insights and understanding of the chiral/achiral designations (nomenclatures), the stereochemical features, and related properties of the natural and synthetic products. Without having an adequate knowledge of stereochemical concepts, it will not be possible to understand and appreciate the stereochemistry of natural or synthetic products. Thus, essential static and dynamic aspects of stereochemistry with sufficient illustrative examples along with discussions are presented. The structure of the monograph allows for easy selection of separate topics for reading and teaching. This book will also provide an idea of basic stereochemical concepts, as applied to organic molecules in general as well as to organic ligands in coordination complexes, and will, therefore, be valuable resources to teachers and students of advanced undergraduates and post-graduates, researchers, and professionals.

Stereochemistry of Organic Compounds

Stereochemistry of Organic Compounds
Author: D. Nasipuri
Publisher: John Wiley & Sons
Total Pages: 554
Release: 1991
Genre: Science
ISBN:

This text deals with the new concepts and terminology that have been introduced into the treatment of organic stereochemistry over the last decade. Organic reaction mechanisms, as they relate to stereochemistry, are included, and the pericyclic reaction using the frontier molecular orbital approach is explained. The text does not assume a strong grounding in organic chemistry and will therefore be useful to a broader spectrum of students - both graduate and undergraduate. The volume features numerous illustrations and programmed problems.