Small Animal Imaging

Small Animal Imaging
Author: Fabian Kiessling
Publisher: Springer
Total Pages: 871
Release: 2017-05-22
Genre: Medical
ISBN: 3319422022

This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes
Author: Franco Cataldo
Publisher: Springer Science & Business Media
Total Pages: 411
Release: 2008-09-08
Genre: Science
ISBN: 140206845X

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications. The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

NMR and MRI of Gels

NMR and MRI of Gels
Author: Yves De Deene
Publisher: Royal Society of Chemistry
Total Pages: 426
Release: 2020-07-07
Genre: Science
ISBN: 1788019202

Gels are used in a large variety of commercial and scientific products from drug delivery systems and food science to biomedical sensors. They also are invaluable in MRI physics research where they mimic biological tissue and in radiotherapy quality assurance where they are used to capture the three dimensional radiation dose distribution. This unique book discusses the state-of-the-art of NMR and MRI techniques in studying the physics and chemistry of gel systems, in their application as MRI phantoms and as three dimensional radiation dosimeters. The first part of the book will cover the fundamental physical concepts of gels and the NMR techniques to study gel systems. The second part is dedicated to the application of gels in the life sciences and in the medical practice to validate radiotherapy and new MRI techniques. Filling the gap in literature, this volume provides the scientific reader with an extensive overview of possible techniques and methods to study the interesting properties and applications of gels. For the MRI researcher and medical physicist, the book will be a valuable resource in using gel phantoms for validating contemporary MRI techniques and radiotherapy treatments.

Fundamentals of Ionizing Radiation Dosimetry

Fundamentals of Ionizing Radiation Dosimetry
Author: Pedro Andreo
Publisher: John Wiley & Sons
Total Pages: 226
Release: 2017-06-14
Genre: Science
ISBN: 3527811044

Fosters a thorough understand of radiation dosimetry concepts: detailed solutions to the exercises in the textbook Fundamentals of Ionizing Radiation Dosimetry!

Iron Oxide Nanoparticles for Biomedical Applications

Iron Oxide Nanoparticles for Biomedical Applications
Author: Sophie Laurent
Publisher: Elsevier
Total Pages: 0
Release: 2017-10-10
Genre: Technology & Engineering
ISBN: 9780081019252

Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine.

Magnetic Fluid Hyperthermia

Magnetic Fluid Hyperthermia
Author: Ulrich Engelmann
Publisher:
Total Pages: 302
Release: 2019-03-07
Genre:
ISBN: 9783945954584

Magnetic fluid hyperthermia (MFH) uses magnetic nanoparticles (MNP) to transform the energy of an alternating magnetic field into heat via magnetic relaxation. This enables organ-confined cancer treatment by delivering cell-damaging temperatures higher than 43°C inside tumors. However, MNP-cell interaction restricts MNP mobility and causes MNP agglomeration, severely limiting the MNP heating behavior. Based on in vitro experiments, this book addresses the applicability of MFH to pancreatic tumor cells and discusses optimizations of intracellular MNP heating for clinical application. The impact of MNP-cell interaction on heating efficiency is quantified and compared to MNP systems mimicking intracellular conditions. Besides, Monte-Carlo simulation of MNP magnetic relaxation is used to predict optimal field parameters and MNP properties to maximize MFH efficiency under medical constraints.

Radiation Effects on Polymers

Radiation Effects on Polymers
Author: Roger Lee Clough
Publisher:
Total Pages: 656
Release: 1991
Genre: Science
ISBN:

Here is the most extensive resource on polymer radiation effects to be available in more than a decade. This new volume reviews the fundamental chemistry and physics of polymer-radiation interaction and examines recent progress in most major areas of the field. Its 38 chapters, written by leading experts from around the world, cover: fundamentals of polymer radiation chemistry; technological applications of radiation to polymers (including radiation processing; radiation curing; sterilization; cross-linking, polymerization, grafting, X-ray resists, and others); and degradation of stabilization of irradiated polymers (including nuclear plants, scintillation detectors for particle physics, and others).

World Congress on Medical Physics and Biomedical Engineering 2018

World Congress on Medical Physics and Biomedical Engineering 2018
Author: Lenka Lhotská
Publisher:
Total Pages:
Release: 2019
Genre: Biomedical engineering
ISBN: 9789811090363

This book presents the proceedings of the IUPESM World Congress on Biomedical Engineering and Medical Physics, a tri-annual high-level policy meeting dedicated exclusively to furthering the role of biomedical engineering and medical physics in medicine. The book offers papers about emerging issues related to the development and sustainability of the role and impact of medical physicists and biomedical engineers in medicine and healthcare. It provides a unique and important forum to secure a coordinated, multileveled global response to the need, demand, and importance of creating and supporting strong academic and clinical teams of biomedical engineers and medical physicists for the benefit of human health.