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| Author | : Krishnarao Appasani |
| Publisher | : Cambridge University Press |
| Total Pages | : 449 |
| Release | : 2016-01-14 |
| Genre | : Medical |
| ISBN | : 1107042763 |
Experts from academia and industry highlight the potential of genome-wide association studies from basic science to clinical and biotechnological/pharmaceutical applications.
| Author | : Xinghua Mindy Shi |
| Publisher | : Humana |
| Total Pages | : 252 |
| Release | : 2021-01-02 |
| Genre | : Science |
| ISBN | : 9781071600283 |
This volume details state-of-art eQTL analysis, where interdisciplinary researchers are provided both theoretical and practical guidance to eQTL analysis and interpretation. Chapters guide readers through methods and tools for eQTL and QTL analysis and the usage of such analysis in various scenarios. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, eQTL Analysis: Methods and Protocols to ensure successful results in the further study of this vital field.
| Author | : Veronica van Heyningen |
| Publisher | : Academic Press |
| Total Pages | : 415 |
| Release | : 2011-09-02 |
| Genre | : Science |
| ISBN | : 0080877818 |
Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer
| Author | : Karl W. Broman |
| Publisher | : Springer |
| Total Pages | : 400 |
| Release | : 2011-12-02 |
| Genre | : Science |
| ISBN | : 9781461417088 |
Comprehensive discussion of QTL mapping concepts and theory Detailed instructions on the use of the R/qtl software, the most featured and flexible software for QTL mapping Two case studies illustrate QTL analysis in its entirety
| Author | : Michael Lynch |
| Publisher | : Sinauer Associates Incorporated |
| Total Pages | : 980 |
| Release | : 1998-01 |
| Genre | : Science |
| ISBN | : 9780878934812 |
Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.
| Author | : Trygve Tollefsbol |
| Publisher | : Academic Press |
| Total Pages | : 944 |
| Release | : 2016-06-21 |
| Genre | : Science |
| ISBN | : 0128032405 |
Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine
| Author | : Keith DiPetrillo |
| Publisher | : Methods in Molecular Biology |
| Total Pages | : 368 |
| Release | : 2009-09-25 |
| Genre | : Medical |
| ISBN | : |
The first section of this guide provides methods for cardiovascular phenotyping of rodent models; the second section covers bioinformatic integration of phenotypde data with genome-wide genotype and expression data. Chapters include step-by-step protocols.
| Author | : Rongling Wu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 371 |
| Release | : 2007-07-17 |
| Genre | : Science |
| ISBN | : 038768154X |
This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.
| Author | : Paul Maria Selzer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 297 |
| Release | : 2008-01-18 |
| Genre | : Science |
| ISBN | : 3540728007 |
At last, here is a baseline book for anyone who is confused by cryptic computer programs, algorithms and formulae, but wants to learn about applied bioinformatics. Now, anyone who can operate a PC, standard software and the internet can also learn to understand the biological basis of bioinformatics, of the existence as well as the source and availability of bioinformatics software, and how to apply these tools and interpret results with confidence. This process is aided by chapters that introduce important aspects of bioinformatics, detailed bioinformatics exercises (including solutions), and to cap it all, a glossary of definitions and terminology relating to bioinformatics.
| Author | : Sir Ronald Aylmer Fisher |
| Publisher | : |
| Total Pages | : 172 |
| Release | : 1965 |
| Genre | : Genetics |
| ISBN | : |
Segregating inbreed lines; Progress towards homozygosity; Various systems of inbreeding; Junctions; Appendix.
