Spline Models for Observational Data

Spline Models for Observational Data
Author: Grace Wahba
Publisher: SIAM
Total Pages: 174
Release: 1990-09-01
Genre: Mathematics
ISBN: 0898712440

This book serves well as an introduction into the more theoretical aspects of the use of spline models. It develops a theory and practice for the estimation of functions from noisy data on functionals. The simplest example is the estimation of a smooth curve, given noisy observations on a finite number of its values. Convergence properties, data based smoothing parameter selection, confidence intervals, and numerical methods are established which are appropriate to a number of problems within this framework. Methods for including side conditions and other prior information in solving ill posed inverse problems are provided. Data which involves samples of random variables with Gaussian, Poisson, binomial, and other distributions are treated in a unified optimization context. Experimental design questions, i.e., which functionals should be observed, are studied in a general context. Extensions to distributed parameter system identification problems are made by considering implicitly defined functionals.

Multivariate Splines

Multivariate Splines
Author: Charles K. Chui
Publisher: SIAM
Total Pages: 192
Release: 1988-01-01
Genre: Mathematics
ISBN: 0898712262

Subject of multivariate splines presented from an elementary point of view; includes many open problems.

Smoothing Spline ANOVA Models

Smoothing Spline ANOVA Models
Author: Chong Gu
Publisher: Springer
Total Pages: 0
Release: 2015-06-25
Genre: Mathematics
ISBN: 9781489989840

Nonparametric function estimation with stochastic data, otherwise known as smoothing, has been studied by several generations of statisticians. Assisted by the ample computing power in today's servers, desktops, and laptops, smoothing methods have been finding their ways into everyday data analysis by practitioners. While scores of methods have proved successful for univariate smoothing, ones practical in multivariate settings number far less. Smoothing spline ANOVA models are a versatile family of smoothing methods derived through roughness penalties, that are suitable for both univariate and multivariate problems. In this book, the author presents a treatise on penalty smoothing under a unified framework. Methods are developed for (i) regression with Gaussian and non-Gaussian responses as well as with censored lifetime data; (ii) density and conditional density estimation under a variety of sampling schemes; and (iii) hazard rate estimation with censored life time data and covariates. The unifying themes are the general penalized likelihood method and the construction of multivariate models with built-in ANOVA decompositions. Extensive discussions are devoted to model construction, smoothing parameter selection, computation, and asymptotic convergence. Most of the computational and data analytical tools discussed in the book are implemented in R, an open-source platform for statistical computing and graphics. Suites of functions are embodied in the R package gss, and are illustrated throughout the book using simulated and real data examples. This monograph will be useful as a reference work for researchers in theoretical and applied statistics as well as for those in other related disciplines. It can also be used as a text for graduate level courses on the subject. Most of the materials are accessible to a second year graduate student with a good training in calculus and linear algebra and working knowledge in basic statistical inferences such as linear models and maximum likelihood estimates.

Nonparametric Regression and Spline Smoothing, Second Edition

Nonparametric Regression and Spline Smoothing, Second Edition
Author: Randall L. Eubank
Publisher: CRC Press
Total Pages: 368
Release: 1999-02-09
Genre: Mathematics
ISBN: 9780824793371

Provides a unified account of the most popular approaches to nonparametric regression smoothing. This edition contains discussions of boundary corrections for trigonometric series estimators; detailed asymptotics for polynomial regression; testing goodness-of-fit; estimation in partially linear models; practical aspects, problems and methods for confidence intervals and bands; local polynomial regression; and form and asymptotic properties of linear smoothing splines.

Spline Regression Models

Spline Regression Models
Author: Lawrence C. Marsh
Publisher: SAGE
Total Pages: 86
Release: 2001-09-14
Genre: Social Science
ISBN: 9780761924203

Spline Regression Models shows how to use dummy variables to formulate and estimate spline regression models both in situations where the number and location of the spline knots are known in advance, and where estimation is required.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide
Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
Total Pages: 236
Release: 2013-02-21
Genre: Medical
ISBN: 1587634236

This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Mixed Effects Models for Complex Data

Mixed Effects Models for Complex Data
Author: Lang Wu
Publisher: CRC Press
Total Pages: 431
Release: 2009-11-11
Genre: Mathematics
ISBN: 9781420074086

Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.

Smoothness Priors Analysis of Time Series

Smoothness Priors Analysis of Time Series
Author: Genshiro Kitagawa
Publisher: Springer Science & Business Media
Total Pages: 265
Release: 2012-12-06
Genre: Mathematics
ISBN: 1461207614

Smoothness Priors Analysis of Time Series addresses some of the problems of modeling stationary and nonstationary time series primarily from a Bayesian stochastic regression "smoothness priors" state space point of view. Prior distributions on model coefficients are parametrized by hyperparameters. Maximizing the likelihood of a small number of hyperparameters permits the robust modeling of a time series with relatively complex structure and a very large number of implicitly inferred parameters. The critical statistical ideas in smoothness priors are the likelihood of the Bayesian model and the use of likelihood as a measure of the goodness of fit of the model. The emphasis is on a general state space approach in which the recursive conditional distributions for prediction, filtering, and smoothing are realized using a variety of nonstandard methods including numerical integration, a Gaussian mixture distribution-two filter smoothing formula, and a Monte Carlo "particle-path tracing" method in which the distributions are approximated by many realizations. The methods are applicable for modeling time series with complex structures.

Bayesian Regression Modeling with INLA

Bayesian Regression Modeling with INLA
Author: Xiaofeng Wang
Publisher: CRC Press
Total Pages: 312
Release: 2018-01-29
Genre: Mathematics
ISBN: 1351165755

INLA stands for Integrated Nested Laplace Approximations, which is a new method for fitting a broad class of Bayesian regression models. No samples of the posterior marginal distributions need to be drawn using INLA, so it is a computationally convenient alternative to Markov chain Monte Carlo (MCMC), the standard tool for Bayesian inference. Bayesian Regression Modeling with INLA covers a wide range of modern regression models and focuses on the INLA technique for building Bayesian models using real-world data and assessing their validity. A key theme throughout the book is that it makes sense to demonstrate the interplay of theory and practice with reproducible studies. Complete R commands are provided for each example, and a supporting website holds all of the data described in the book. An R package including the data and additional functions in the book is available to download. The book is aimed at readers who have a basic knowledge of statistical theory and Bayesian methodology. It gets readers up to date on the latest in Bayesian inference using INLA and prepares them for sophisticated, real-world work. Xiaofeng Wang is Professor of Medicine and Biostatistics at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and a Full Staff in the Department of Quantitative Health Sciences at Cleveland Clinic. Yu Ryan Yue is Associate Professor of Statistics in the Paul H. Chook Department of Information Systems and Statistics at Baruch College, The City University of New York. Julian J. Faraway is Professor of Statistics in the Department of Mathematical Sciences at the University of Bath.