Indole Alkaloids

Indole Alkaloids
Author: Maliha Uroos
Publisher: Elsevier
Total Pages: 236
Release: 2022-01-30
Genre: Science
ISBN: 0323972489

Indole Alkaloids: Spirooxindole details the multistep synthesis of natural products using schematic diagrams, providing a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. As a volume in the Visual Guides to Natural Product Synthesis series, this book presents the schematic total syntheses of natural products containing a “spirooxindole” core structure. It covers spirooxindole molecules through visual diagrams, highlighting key steps involved in total, formal and semi-syntheses. Sections cover Brevianamide A and B, Citrinadin A and B, Coerulescine and Horsfiline, Elacomine and Isoelacomine, Gelsemine, Paraherquamide A and B, Rynchophylline, Isorynchophylline, and more. Visual layouts provide quick-and- easy access to developed synthetic routes towards the targeted spirooxindoles. Outlines synthetic strategies for natural products bearing a spirooxindole core structure Includes schematic diagrams of multistep synthetic routes, highlighting key steps along the way Describes all routes for the formal synthesis, semi-synthesis and total synthesis of spirooxindole alkaloids

Spirooxindole Alkaloids

Spirooxindole Alkaloids
Author: Zachary Poulos
Publisher: LAP Lambert Academic Publishing
Total Pages: 280
Release: 2014-09-12
Genre:
ISBN: 9783659598791

Oxindoles and spirooxindoles are important synthetic targets due to their significant biological activity and intriguing physical properties. The development of methods to access spirooxindoles remains an ongoing synthetic challenge, especially in the context of enantioselective catalytic approaches. A review of oxindole alkaloids and major novel methods applied in the arena of their total synthesis is presented in this text.

Spirooxindole

Spirooxindole
Author: Gautam Patel
Publisher: Elsevier
Total Pages: 660
Release: 2024-06-28
Genre: Technology & Engineering
ISBN: 0443223254

Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield. Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book. Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds Highlights green synthesis and nanocatalysis Describes in-depth various medicinal applications Covers both synthesis and applications

The Alkaloids

The Alkaloids
Author: R. H. F. Manske
Publisher: Elsevier
Total Pages: 878
Release: 2014-05-12
Genre: Medical
ISBN: 1483222004

The Alkaloids: Chemistry and Physiology, Volume VIII: The Indole Alkaloids focuses on the advances in the chemistry of indole alkaloids. This book discusses the tryptamine and its derivatives, postulated biosyntheses of the physostigmine ring system, and source of the alkaloids. The simple lysergic acid amides, mass spectra of mitraphylline and rhynchophylline, and alkaloids of gelsemium species are also elaborated. This text likewise covers the determination of the structure of the alkaloids, stereochemistry of cinchonamine, dimeric alkaloids of calabash curare, and chemistry of the reserpine group. Other topics include the biology of ergot and short history of its active principles up to the discovery of ergotamine. This volume is recommended for chemists and researchers interested in indole alkaloids.

Spiro Compounds

Spiro Compounds
Author: Ramon Rios Torres
Publisher: John Wiley & Sons
Total Pages: 468
Release: 2022-03-02
Genre: Science
ISBN: 1119567637

SPIRO COMPOUNDS A comprehensive treatment of the latest research in, and applications of, spiro compounds Spiro Compounds: Synthesis and Applications combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies. With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as: The history, significance, and unique properties of spiro compounds The most important methodologies for their synthesis The applications of spiro compounds in organic chemistry, biology, drug discovery The most important syntheses of natural products bearing a spiro ring Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.

The Alkaloids

The Alkaloids
Author:
Publisher: Academic Press
Total Pages: 252
Release: 2018-02-15
Genre: Science
ISBN: 0128151471

The Alkaloids, Volume 79 is the latest in a series that has covered the topic for more than 60 years. It is considered to be the leading book series in the field of alkaloid chemistry, with more than 70 volumes that cover all aspects of alkaloids, including their chemistry, biology and pharmacology. Each release includes high-quality, timeless reviews written by renowned experts in the field, with this release focusing on pyrrolizidine alkaloids. Contains the latest information on the study of alkaloids Covers their chemistry, biology, pharmacology and medical applications Presents more than 70 volumes in this interesting field of study

The Isoquinoline Alkaloids

The Isoquinoline Alkaloids
Author: K. W. Bentley
Publisher: Elsevier
Total Pages: 273
Release: 2014-04-24
Genre: Science
ISBN: 1483152235

The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.