Specificity In Biological Interactions
Download Specificity In Biological Interactions full books in PDF, epub, and Kindle. Read online free Specificity In Biological Interactions ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Specificity in Biological Interactions
Author | : A. Pullman |
Publisher | : Springer Science & Business Media |
Total Pages | : 344 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9400964579 |
Proceedings of a Working Group at the Pontifical Academy of Sciences, November 9-11, 1983
Essentials of Glycobiology
Author | : Ajit Varki |
Publisher | : CSHL Press |
Total Pages | : 694 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 9780879696818 |
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Protein-protein Recognition
Author | : Colin Kleanthous |
Publisher | : Frontiers in Molecular Biology |
Total Pages | : 370 |
Release | : 2000 |
Genre | : Carrier proteins |
ISBN | : 9780199637607 |
The purpose of Protein-Protein Recognition is to bring together concepts and systems pertaining to protein-protein interactions in a single unifying volume. In the light of the information from the genome sequencing projects and the increase in structural information it is an opportune time totry to make generalizations about how and why proteins form complexes with each other. The emphasis of the book is on heteromeric complexes (complexes in which each of the components can exist in an unbound state) and will use well-studied model systems to explain the processes of formingcomplexes. After an introductory section on the kinetics, thermodynamics, analysis, and classification of protein-protein interactions, weak, intermediate, and high affinity complexes are dealt with in turn. Weak affinity complexes are represented by electron transfer proteins and integrincomplexes. Anti-lysozyme antibodies, the MHC proteins and their interactions with T-cell receptors, and the protein interactions of eukaryotic signal transduction are the systems used to explain complexes with intermediate affinities. Finally, tight binding complexes are represented by theinteraction of protein inhibitors with serine proteases and by nuclease inhibitor complexes. Throughout the chapters common themes are the technologies which have had the greatest impact, how specificity is determined, how complexes are stabilized, and medical and industrial applications.
RNA-protein Interactions
Author | : Kiyoshi Nagai |
Publisher | : Oxford University Press, USA |
Total Pages | : 302 |
Release | : 1994 |
Genre | : Medical |
ISBN | : |
The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.
Biodefense in the Age of Synthetic Biology
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 189 |
Release | : 2019-01-05 |
Genre | : Technology & Engineering |
ISBN | : 0309465184 |
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Protein Engineering
Author | : Peter C. E. Moody |
Publisher | : IRL Press |
Total Pages | : 104 |
Release | : 1990 |
Genre | : Science |
ISBN | : |
The aim of protein engineering is to improve or alter the properties of proteins in a rational, pre-determined way. This requires an understanding of the scope, structure, and function of proteins. The increasing importance of the subject is reflected in the widening range of courses coveringthe topic. This book provides a clear, up-to-date review of the subject and explains the principles and applications. Topics covered include analysis of mutant proteins, understanding of structure-activity relationships, and the application of protein engineering to industrial and medical problems.
Research at the Intersection of the Physical and Life Sciences
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 122 |
Release | : 2010-03-25 |
Genre | : Science |
ISBN | : 0309147514 |
Traditionally, the natural sciences have been divided into two branches: the biological sciences and the physical sciences. Today, an increasing number of scientists are addressing problems lying at the intersection of the two. These problems are most often biological in nature, but examining them through the lens of the physical sciences can yield exciting results and opportunities. For example, one area producing effective cross-discipline research opportunities centers on the dynamics of systems. Equilibrium, multistability, and stochastic behavior-concepts familiar to physicists and chemists-are now being used to tackle issues associated with living systems such as adaptation, feedback, and emergent behavior. Research at the Intersection of the Physical and Life Sciences discusses how some of the most important scientific and societal challenges can be addressed, at least in part, by collaborative research that lies at the intersection of traditional disciplines, including biology, chemistry, and physics. This book describes how some of the mysteries of the biological world are being addressed using tools and techniques developed in the physical sciences, and identifies five areas of potentially transformative research. Work in these areas would have significant impact in both research and society at large by expanding our understanding of the physical world and by revealing new opportunities for advancing public health, technology, and stewardship of the environment. This book recommends several ways to accelerate such cross-discipline research. Many of these recommendations are directed toward those administering the faculties and resources of our great research institutions-and the stewards of our research funders, making this book an excellent resource for academic and research institutions, scientists, universities, and federal and private funding agencies.
The Specificity of Serological Reactions
Author | : Karl Landsteiner |
Publisher | : Courier Corporation |
Total Pages | : 372 |
Release | : 2013-09-25 |
Genre | : Science |
ISBN | : 0486151441 |
Nobel prizewinner's account of experiments he and colleagues carried out on antigens and serological reactions with simple compounds. Exceptionally broad coverage of basic immunology. Extensive bibliography.
Computational Systems Biology
Author | : Andres Kriete |
Publisher | : Academic Press |
Total Pages | : 549 |
Release | : 2013-11-26 |
Genre | : Science |
ISBN | : 0124059384 |
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.