Some Recollections of Gap Jumping

Some Recollections of Gap Jumping
Author: Derek H. R. Barton
Publisher:
Total Pages: 176
Release: 1991
Genre: Biography & Autobiography
ISBN:

Nobel Laureate Sir Derek Barton discusses his scientific career, which embraced tenures as Professor at Imperial College, London for 20 years before becoming Director of Research at the CNRS at Gif-sur-Yvette, France for a decade, and now professor at Texas A&M University. Barton highlights his work in natural products synthesis and structure identification, his development of novel synthetic reactions, and his recent research in radical chemistry. His volume is laced with numerous anecdotes about many famous chemists and contains 49 photographs.

Half a Century of Free Radical Chemistry

Half a Century of Free Radical Chemistry
Author: Derek H. R. Barton
Publisher: Cambridge University Press
Total Pages: 180
Release: 1993-04-15
Genre: Science
ISBN: 9780521445801

This book describes the experience over 25 years of the senior author with the chemistry of organic free radicals. It begins with a mechanistic study of industrial importance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. There follows 20 years of practical work to prove the theory correct, especially in the case of morphine alkaloids. The book then describes the work on nitrile photolysis (Barton reaction) which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. There follows a description of the invention of an important new method for the deoxygenation of biologically important molecules, especially sugars and nucleosides, using radical chemistry applied to thiocarbonyl derivatives. Some years later, in a logical extension to carboxylic acids, another new reaction was invented which provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.

The Bartonian Legacy

The Bartonian Legacy
Author: Pierre Potier
Publisher: World Scientific
Total Pages: 161
Release: 2000-12-18
Genre: Science
ISBN: 1783261595

The Bartonian Legacy is a collection of memoirs, reminiscences and biographical details regarding Sir Derek Barton (1918-1998) who was one of the most influential organic chemists of the 20th Century. The chapters are contributed by some of his many students, coworkers and scientific colleagues, all of whom testify to his fascinating character and true genius. It offers intimate glimpses at Sir Derek's scientific life, his sense of humor and his modus operandi as a teacher of research methods. The volume will serve as a valuable companion work to the more official biographies and obituaries, several of which have already been published./a

Triumph of the Heart

Triumph of the Heart
Author: Jie Jack Li
Publisher: Oxford University Press
Total Pages: 220
Release: 2009-04-03
Genre: Medical
ISBN: 0198043511

Over 25 million people in the U.S. alone have benefited from statins--such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines--in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, Triumph of the Heart offers a compelling view of one of the most important drug discoveries of our time.

Chemical History

Chemical History
Author: Gerrylyn K Roberts
Publisher: Royal Society of Chemistry
Total Pages: 261
Release: 2007-10-31
Genre: Science
ISBN: 1847552633

This book provides an historical overview of the recent developments in the history of diverse fields within chemistry. It follows on from Recent Developments in the History of Chemistry, a volume published in 1985. Covering chiefly the last 20 years, the primary aim of Chemical History: Reviews of the Recent Literature is to familiarise newcomers to the history of chemistry with some of the more important developments in the field. Starting with a general introduction and look at the early history of chemistry, subsequent chapters go on to investigate the traditional areas of chemistry (physical, organic, inorganic) alongside analytical chemistry, physical organic chemistry, medical chemistry and biochemistry, and instruments and apparatus. Topics such as industrial chemistry and chemistry in national contexts, whilst not featuring as separate chapters, are woven throughout the content. Each chapter is written by experts and is extensively referenced to the international chemical literature. Chemical History: Reviews of the Recent Literature is also ideal for chemists who wish to become familiar with historical aspects of their work. In addition, it will appeal to a wider audience interested in the history of chemistry, as it draws together historical materials that are widely scattered throughout the chemical literature.

Name Reactions

Name Reactions
Author: Jie Jack Li
Publisher: Springer Science & Business Media
Total Pages: 483
Release: 2013-11-11
Genre: Science
ISBN: 3662053365

This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.

Robert Burns Woodward

Robert Burns Woodward
Author: Otto Theodor Benfey
Publisher: Chemical Heritage Foundation
Total Pages: 508
Release: 2001
Genre: Biography & Autobiography
ISBN: 9780941901253

Robert Burns Woodward was the star of 20th-century organic chemistry. An MIT graduate by age 19, Woodward's ingenious notions about organic synthesis and his artful methodology were astounding. He is most famed for his synthesis of vitamin B12,which he undertook with Albert Eschenmoser, and for the orbital symmetry rules he developed with Roald Hoffmann. This volume presents Woodward's most celebrated papers and lectures--including the famous Cope lecture. Insightful commentaries and rarely seen photographs are also included.

Organic Conformational Analysis and Stereochemistry from Circular Dichroism Spectroscopy

Organic Conformational Analysis and Stereochemistry from Circular Dichroism Spectroscopy
Author: David A. Lightner
Publisher: John Wiley & Sons
Total Pages: 508
Release: 2000-03-31
Genre: Science
ISBN: 9780471354055

Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten; sie geben beispielsweise Auskunft über die Konformation organischer Verbindungen. Dieses Buch richtet sich an den organischen Chemiker, der mit den Grundprinzipien der Stereochemie vertraut ist, und erläutert die Anwendung der CD-Spektroskopie zur Konformationsanalyse ausführlich und verständlich. (06/00)

Candid Science: Conversations With Famous Chemists

Candid Science: Conversations With Famous Chemists
Author: Istvan Hargittai
Publisher: World Scientific
Total Pages: 530
Release: 2000-01-26
Genre: Science
ISBN: 1783262141

In this book, 36 famous chemists, including 18 Nobel laureates, tell about their lives in science, the beginnings of their careers, their aspirations, and their hardships and triumphs. The reader will learn about their seminal discoveries, and the conversations in the book bring out the humanity of these great scientists. NMR spectroscopy, computational chemistry, the drama of buckminsterfullerene, the story of the Pill, the politics of atmospheric chemistry and the resonance theory, the beginnings of molecular mechanics and modern stereochemistry are examples of the topics discussed first-hand by, in all likelihood, the most appropriate persons.