Somatostatin and Its Receptors

Somatostatin and Its Receptors
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
Total Pages: 284
Release: 2008-04-30
Genre: Science
ISBN: 0470514744

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical implications. The book will provide a comprehensive summary of the cellular and molecular biology of somatostatin and its recently isolated receptors. The book will review the design and use of specific somatostatin analogues both biochemically to characterize the specific functions of somatostatin and clinically in the treatment of various tumors.

Principles of Bone Biology

Principles of Bone Biology
Author: John P. Bilezikian
Publisher: Academic Press
Total Pages: 2074
Release: 2008-09-29
Genre: Medical
ISBN: 0080568750

Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Handbook of Neuroendocrinology

Handbook of Neuroendocrinology
Author: George Fink
Publisher: Academic Press
Total Pages: 895
Release: 2012
Genre: Medical
ISBN: 0123750970

Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Somatostatin Analogues

Somatostatin Analogues
Author: Alicja Hubalewska-Dydejczyk
Publisher: John Wiley & Sons
Total Pages: 379
Release: 2015-06-11
Genre: Science
ISBN: 111903163X

Featuring chapters from specialists in endocrinology, physiology, pathology, and nuclear medicine, this book provides a multidisciplinary approach to a wide variety of issues concerning somatostatin and its analogues. The book: Provides the most up-to-date coverage of somatostatin analog use in diagnostic and therapy Integrating the specialties of endocrinology, physiology, pathology, and nuclear medicine, providing the multidisciplinary approach to the topic Focuses on future applications, novel compounds, and areas for further research Covers topics by authors who are renowned experts and researchers in the field

Gigantism and Acromegaly

Gigantism and Acromegaly
Author: Constantine A. Stratakis
Publisher: Academic Press
Total Pages: 312
Release: 2021-06-01
Genre: Medical
ISBN: 0128145382

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism

Nuclear Medicine: The Requisites

Nuclear Medicine: The Requisites
Author: Harvey A. Ziessman, MD
Publisher: Elsevier Health Sciences
Total Pages: 466
Release: 2013-03-21
Genre: Medical
ISBN: 0323082998

Get the essential tools you need to make an accurate diagnosis with Nuclear Medicine: The Requisites! The newest edition of his bestselling volume by Drs. Harvey Ziessman, Janis O'Malley, and James Thrall delivers the conceptual, factual, and interpretive information you need for effective clinical practice in nuclear medicine imaging, as well as for certification and recertification review. Prepare for the written board exam and for clinical practice with critical information on nuclear medicine physics, detection and instrumentation, SPECT and PET imaging, and clinical nuclear medicine imaging. Get the best results from today's most technologically advanced approaches, including hybrid imaging, PET/CT, and SPECT/CT, as well as recent developments in instrumentation, radiopharmaceuticals, and molecular imaging. Clearly visualize the findings you're likely to see in practice and on exams with nearly 200 vibrant new full-color images. Access the fully searchable text and downloadable images online at www.expertconsult.com.

Meningiomas E-Book

Meningiomas E-Book
Author: M. Necmettin Pamir
Publisher: Elsevier Health Sciences
Total Pages: 798
Release: 2010-01-25
Genre: Medical
ISBN: 1455708992

Meningiomas, by M. Necmettin Pamir, MD, Peter M. Black, MD, PhD, and Rudolf Fahlbusch, MD, presents current and comprehensive guidance on this most common, yet clinically challenging type of brain tumor. Written and edited by the world’s most prominent brain tumor neurosurgeons, it helps you to not only determine the type and location of the tumor, but also the most ideal surgical approach to provide your patients with the best outcomes. An extensive collection of surgical photographs covers unique and original cases, while discussions of pre-surgical techniques and approaches emphasize decision making with the help of all imaging modalities and analysis of symptoms and patient history. Expert Consult functionality enhances your reference power with convenient online access to the complete text and illustrations from the book, along with videos that depict surgical techniques in real time. Provides access to the complete text online—fully searchable, along with all of the illustrations downloadable for your personal presentations, and real-time surgical videos covering microscopic extended endonasal approach to suprasellar meningioma, and more, at expertconsult.com. Covers today’s full range of management methods, including adjuvant therapies, providing you with the best strategies for obtaining optimal outcomes. Features the work of the world’s most prominent brain tumor neurosurgeons—a completely international authorship—bringing you the best procedures globally. Offers an in-depth section on surgical methods and approaches based upon tumor location, to help you in the decision-making process. Includes coverage of spinal meningiomas including pre-diagnosis symptoms and outcomes.

Canine and Feline Endocrinology - E-Book

Canine and Feline Endocrinology - E-Book
Author: Edward C. Feldman
Publisher: Elsevier Health Sciences
Total Pages: 688
Release: 2014-11-14
Genre: Medical
ISBN: 1455744573

No other title offers such dedication to the depth, experience, and focus of endocrinology as Canine and Feline Endocrinology, 4th Edition. Comprehensive coverage includes virtually every common and uncommon condition in endocrinology, plus the most updated information on nutrition, geriatric care, pathophysiology, testing procedures, and cost-effective and expedient diagnostic protocols. With its logical, step-by-step guidance for decision making, diagnosis, and prescribing, you will be well-equipped to care for the wide spectrum of endocrine and metabolic disorders in dogs and cats. Expert authorship, including the addition of three world-renowned endocrinology experts — Claudia Reusch, Catharine Scott-Moncrieff, and Ellen Behrend — offers unparalleled guidance on the latest advances in the field. Separation of cats and dogs into separate chapters ensures information on each species is covered to its fullest. Focus on diagnosis and treatment with less discussion on anatomy and physiology allows the book to concentrate on practical, current information that today’s clinician most use. Thorough coverage of indications and interpretation of testing procedures in endocrine diseases enables reliable and accurate diagnosis. Detailed discussions of diagnostic strategies and treatment recommendations provide practical, cost-effective, and expedient approaches while ensuring they represent standard of care backed by research and experience. Algorithms on diagnostic and therapeutic approaches provide a practical, logical resource for the busy practitioner needing quick access to information. Logical, step-by-step guidelines aid in accurate decision-making and diagnosis. Comprehensive tables and boxes summarize and clarify key information for quick reference. In-depth discussions from experts in the field include coverage of treatment, monitoring, and management of complications as well as clinical signs, differential diagnoses and diagnostic approaches Extensive reference lists provide readers with sources for additional information on clinical investigative studies Separate chapters devoted to each key topic provide thorough, distinct coverage of all content areas. NEW! Updated content includes the latest information on: thyroid disease; current imaging studies; atypical Addison's disease; atypical Cushing's disease; idiopathic hypercalcemia in cats; insulin therapy in dogs and cats; diagnostics and treatments; and radiotherapy. NEW! Integration of sound nutrition practices into the treatment of endocrine disorders ensures that you have the knowledge you need to efficiently treat these disorders. NEW! Expanded coverage provides more information on geriatric dogs and cats and the latest findings regarding the treatment of diabetes (two factors which are often interrelated).

Growth Hormone in Adults

Growth Hormone in Adults
Author: Anders Juul
Publisher: Cambridge University Press
Total Pages: 536
Release: 2000-04-27
Genre: Medical
ISBN: 9780521641883

This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.

Nitric Oxide Synthase: Characterization and Functional Analysis

Nitric Oxide Synthase: Characterization and Functional Analysis
Author:
Publisher: Academic Press
Total Pages: 375
Release: 1996-09-18
Genre: Science
ISBN: 0080536379

Although the function of nitric oxide in a regulatory capacity in the central and peripheral nervous system is widely recognized, the full scope of its actions and its interrelationships with other classes of regulatory molecules is just beginning to be comprehended. This volume contains a number of sophisticated and advanced methods essential for exploring the activity of nitric oxide in the brain. It will be a valuable tool for the established investigator and for those just entering the field. Comprehensive protocols included for detection of NO and related compounds by chemical, immunohistochemical, and in situ hybridization techniques Newly developed methods for the purification of neuronal and endothelial NO synthase, production of monoclonal antibodies to NO synthase, molecular cloning and expression of NO synthesis, and control of NO synthase gene expression Assessment of NO-mediated functions in neurons, central nervous system, cerebral circulation, synaptic transmission, and vascular tone Calcium imaging by confocal microscopy, evaluation of the effect of NO on iron metabolism, and detection of heme oxygenase-1 and -2 message level and distribution