Somatostatin Analogs In Diagnostics And Therapy
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| Author | : Marek Pawlikowski |
| Publisher | : CRC Press |
| Total Pages | : 114 |
| Release | : 2007-04-03 |
| Genre | : Science |
| ISBN | : 1498713521 |
Somatostatin is a peptide isolated originally from the hypothalamus and considered as an inhibitor of growth hormone secretion. However, further studies have shown that the peptide was ubiquitously distributed and exerts a large spectrum of physiological effects, mostly of an inhibitory nature. The very short half-life of the native peptide limits
| Author | : Alicja Hubalewska-Dydejczyk |
| Publisher | : John Wiley & Sons |
| Total Pages | : 379 |
| Release | : 2015-06-11 |
| Genre | : Science |
| ISBN | : 111903163X |
Featuring chapters from specialists in endocrinology, physiology, pathology, and nuclear medicine, this book provides a multidisciplinary approach to a wide variety of issues concerning somatostatin and its analogues. The book: Provides the most up-to-date coverage of somatostatin analog use in diagnostic and therapy Integrating the specialties of endocrinology, physiology, pathology, and nuclear medicine, providing the multidisciplinary approach to the topic Focuses on future applications, novel compounds, and areas for further research Covers topics by authors who are renowned experts and researchers in the field
| Author | : George Fink |
| Publisher | : Academic Press |
| Total Pages | : 895 |
| Release | : 2012 |
| Genre | : Medical |
| ISBN | : 0123750970 |
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
| Author | : Constantine A. Stratakis |
| Publisher | : Academic Press |
| Total Pages | : 312 |
| Release | : 2021-06-01 |
| Genre | : Science |
| ISBN | : 0128145382 |
Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. - Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism - Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics - Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
| Author | : H. William Strauss |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 873 |
| Release | : 2012-11-27 |
| Genre | : Medical |
| ISBN | : 0387488944 |
This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
| Author | : Andrea Giustina |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 538 |
| Release | : 2000-11-30 |
| Genre | : Medical |
| ISBN | : 9780792372127 |
Growth Hormone and the Heart endeavors to bring together knowledge that has been accumulated in the area of GH and the heart, from basic to clinical studies, by research groups working on this topic throughout the world. Lessons from different experimental models and from several human diseases (acromegaly, adult GH deficiency, heart failure) suggest to endocrinologists and cardiologists that GH may not only have a role in the physiology and pathophysiology of heart function, but that GH itself may have a place in the treatment of primary heart diseases (such as dilated cardiomyopathy) or of cardiac complications of hypopituitarism. Growth Hormone and the Heart will be a useful update of the research produced in the field of cardiovascular endocrinology. The Editors also hope that this book will serve as the primary step in the recognition of the wide physiological and clinical significance of GH and heart interactions.
| Author | : The American Cancer Society |
| Publisher | : John Wiley & Sons |
| Total Pages | : 727 |
| Release | : 2018-05-01 |
| Genre | : Medical |
| ISBN | : 1118517644 |
Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners comprehensively addresses all aspects of clinical management for cancer taking a balanced, authoritative and, -where possible- evidence-based stance and may be used in conjunction with the book, The American Cancer Society's Principles of Oncology: Prevention to Survivorship. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a practical understanding of the field of oncology.
| Author | : Krishan Kumar |
| Publisher | : Mdpi AG |
| Total Pages | : 262 |
| Release | : 2021-12-06 |
| Genre | : |
| ISBN | : 9783036524276 |
Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.
| Author | : Karel Pacak |
| Publisher | : Humana Press |
| Total Pages | : 483 |
| Release | : 2016-12-26 |
| Genre | : Medical |
| ISBN | : 3319460382 |
Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT and PET/CT and PET/MR. Discussing of radionuclide imaging covers the tumors mentioned above, as well as pulmonary and thymic neuroendocrine tumors and medullary thyroid carcinoma. A presentation of radionuclide therapies follows, including 131I-MIBG therapy, somatostatin receptor-based therapy, and alpha radionuclide therapy, as well as the role of nanoparticles. Comprehensive and up-to-date, Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors will assist and guide physicians who encounter patients with these conditions, either from a diagnostic or therapeutic standpoint, and particularly emphasizes the current and emerging medical devices and imaging and therapeutic options.
| Author | : M. Buchfelder |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 166 |
| Release | : 2016-03-21 |
| Genre | : Medical |
| ISBN | : 3318027383 |
Revolutionary changes in medical imaging have enormously improved the ability to detect structural and functional organ alterations early. Imaging is becoming an essential tool - in association with hormonal assays - for the diagnosis and management of endocrine disorders. New contrast media and their application to ultrasounds, as well as the opportunity to merge images acquired by functional/metabolic and traditional techniques, allow characterization of key features of identified lesions. Some radiological techniques such as ultrasonography, CT, and MRI are now available in operating rooms, thus supporting a diagnostic and therapeutic approach to endocrine diseases. In this new book, distinguished experts have contributed concise and well-illustrated chapters to describe pathognomonic features of several benign and malignant diseases affecting endocrine glands. They review the main advantages and disadvantages of each diagnostic technique along with indications for selecting a method. As a special feature, online videos of dynamic diagnostic and therapeutic procedures are available. Imaging in Endocrine Disorders is a must read and valuable reference for all professionals dealing with endocrine disorders, including internists and general practitioners who must manage the essential diagnostic workup.
