Skin Barrier Function
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| Author | : T. Agner |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 172 |
| Release | : 2016-02-04 |
| Genre | : Medical |
| ISBN | : 3318055867 |
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.
| Author | : Peter M. Elias |
| Publisher | : CRC Press |
| Total Pages | : 634 |
| Release | : 2005-09-22 |
| Genre | : Medical |
| ISBN | : 084936129X |
A must-have reference for any researcher or scientist interested in cutaneous protective mechanisms, this guide provides expertly researched chapters on every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and the role of barrier function in diseases such as atopic dermatiti
| Author | : Hans Schaefer |
| Publisher | : S. Karger AG (Switzerland) |
| Total Pages | : 336 |
| Release | : 1996 |
| Genre | : Medical |
| ISBN | : |
Skin Barrier is the first book to be written exclusively by researchers for researchers as a convenient desktop reference. It focuses on several key aspects of the skin barrier including composition and structure and a description of the properties governing the diffusion of compounds across the skin. Although there has been a large number of laboratories involved in measuring percutaneous absorption over the past 15 to 20 years, it is only recently that there has been a general consensus in the scientific community regarding the development of standard protocols. Recognizing the importance of this, the authors have included two chapters detailing the protocol used in measuring and predicting percutaneous absorption and a discussion on the practical application of these techniques to solve associated problems. In order to provide the researcher and especially the student with access to more detailed information, the book features a comprehensive listing of references published over the past 10 years. Skin Barrier is the only desktop reference for dermatologists, cosmetologists, biochemists, biologists, and those in the pharmaceutics industry, who need detailed and accurate information about the skin barrier on a daily basis. No R & D department should be without a copy.
| Author | : Peter J. Frosch |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1127 |
| Release | : 2006-06-07 |
| Genre | : Medical |
| ISBN | : 354031301X |
It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a large scale in a short time and keep it regularly updated. The greatest danger period. If the data evaluation shows an unacceptably for a textbook is to become outdated – then it stays high rate of sensitization in the exposed population, on the bookshelf and is rarely consulted. The contin- regulatory measures will be undertaken to protect uous flow of new medicaments, the fascinating the consumer. A recent example is the “methyldib- improvements in diagnostic image analysis and ever- mo glutaronitrile story. ” changing operative procedures are the reasons for These and other issues of importance are covered considerable knowledge deficits in old textbooks, in depth in the newest edition of this textbook.
| Author | : Jean Krutmann |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 203 |
| Release | : 2010-11-08 |
| Genre | : Medical |
| ISBN | : 3642122647 |
This extraordinary reference describes the scientific basis, summarizes the existing evidence that functional food for skin really works, and addresses the key questions asked by dermatologists and patients when it comes to practical aspects of nutrition based strategies in clinical and cosmetical dermatology. It is believed that this helpful guide will become the golden standard, the ‘bible’ for this given topic, which will be used by dermatologists, industry people and interested patients.
| Author | : Marie Loden |
| Publisher | : CRC Press |
| Total Pages | : 472 |
| Release | : 1999-12-06 |
| Genre | : Medical |
| ISBN | : 9780849375200 |
Dry Skin and Moisturizers: Chemistry and Function presents new information relating to skin biochemistry and pathological changes seen in various dry skin disorders. The book examines the pharmacology of ingredients in moisturizing preparations, providing a broad overview of formulations as well as detailed information on ingredients. Featuring contributions from leading researchers from around the world, the book also outlines general principles for testing and evaluation of effects on the skin, with particular emphasis on safety assessment. This comprehensive book is divided into five parts. Part I, Dry Skin and Moisturizers, offers an introduction to this fascinating topic, while Part II, Biochemistry and Function of the Skin, explores everything from particle probes and skin physiology to the distribution and function of physiological elements in skin. Part III focuses on dry skin and hyperkeratotic conditions. Physico-chemical considerations, emulsifiers, hydrophilic pastes, lanolins, and other topics are addressed in Part IV, Formulations and Interactions with the Skin; while safety assessments, human in vivo skin irritancy testing, sensitive skin, and more are examined in Part V, Evaluation and Safety.
| Author | : Georg T. Wondrak |
| Publisher | : Springer |
| Total Pages | : 454 |
| Release | : 2016-08-22 |
| Genre | : Medical |
| ISBN | : 3319431579 |
It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit patients in the near future. Coauthored by recognized international leaders in molecular and clinical biomedical sciences, this novel book provides a comprehensive perspective on environmental exposure-induced skin stress response pathways. Focusing on molecular opportunities targeting skin stress response pathways that are involved in cutaneous barrier function and repair, antimicrobial defense, immune regulation, inflammation, and malignant progression, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in skin health and disease with implications for small molecule therapeutic development.
| Author | : R.M. Marks |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 213 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 9400912919 |
| Author | : Aaron Tabor |
| Publisher | : William Andrew |
| Total Pages | : 582 |
| Release | : 2009-07-30 |
| Genre | : Business & Economics |
| ISBN | : 0815520301 |
Nutritional cosmetics is an emerging area of intense research and marketing and encompasses the concept that orally consumed dietary products can support healthier and more beautiful skin. There are numerous dietary ingredients now being marketed for their potential skin health and beauty benefits and many of these are supported by growing scientific evidence. The purpose of this book is to compile the scientific evidence showing the potential benefits of some of the more extensively researched ingredients. As far as possible, information about the benefits of ingredients consumed orally for skin health is presented. The information contained in this book will help provide insights into an emerging research area and provide scientific background for the potential clinical effectiveness for some of the better researched nutricosmetic ingredients. ABOUT THE EDITORS Aaron Tabor, M.D. is the CEO of Physicians Pharmaceuticals and author of The Revival Slim & Beautiful Diet. A graduate of the Johns Hopkins School of Medicine, Dr. Tabor oversees all clinical research on the Revival Slim & Beautiful Diet plan, conducting randomized, double-blinded, placebo-controlled studies at leading hospitals in the U.S. Areas of note include weight loss, skin/hair/nail appearance, energy, menopause, PMS, cholesterol, memory, and diabetic health. He is also responsible for directing new Revival product development based on clinical research results. Robert M. Blair, Ph.D. is the Research Manager for Physicians Pharmaceuticals, Inc. and manages the daily activities of the Research and Nutrition departments. Dr. Blair received his Ph.D. from Oklahoma State University in the field of Reproductive Physiology. Before joining Physicians Pharmaceuticals, Inc., he worked as an Assistant Professor of Comparative Medicine at the Wake Forest University School of Medicine where he examined the effects of dietary soy on cardiovascular health and cognitive function. Reviews the most-popular and most-researched nutricosmetic ingredients Presents information specifically about the benefits of ingredients consumed orally for skin health Considers the benefits of whey protein, rosemary, soy – and green tea and milk thistle, specifically, for protection against sun damage and photocarcinogenesis Provides information on antioxidants, incl: potential benefits of botanical antioxidants; carotenoids; coenzyme Q10; healthy fruits; olive fruit; and natural enzymes
| Author | : Ichiro Katayama |
| Publisher | : Springer |
| Total Pages | : 368 |
| Release | : 2017-12-06 |
| Genre | : Medical |
| ISBN | : 9811055416 |
This comprehensive guide offers a state-of-the-art overview of basic and clinical aspects of atopic dermatitis (AD). The name "atopic dermatitis" was first used in 1933, and Drs. Lewis Webb Hill and Marion B. Sulzberger presented their report "Evolution of atopic dermatitis" in 1935. Their observations accurately forecasted the contemporary issues in the management of the condition, such as the conclusions that should be drawn from our understanding of the pathogenesis of AD, and the use of steroids as the main treatment. Several aggravating factors have recently been identified, and these also need to be addressed. In this context, the expert contributors to this book describe and discuss the evolution of atopic dermatology from Sulzberger’s era to the present day, including clinical manifestations, etiopathology and treatment. In addition, it explores skin care intervention, the role of microbiom and GWAS studies, and presents unique, previously unpublished cohort studies. It provides insights into the dynamic changes in AD since Sulzberger introduced topical steroids for its treatment. It is a valuable resource for dermatologists, medical practitioners and researchers who are interested in atopic dermatology.
