Sildenafil
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| Author | : Udo Dunzendorfer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 216 |
| Release | : 2004-10-25 |
| Genre | : Architecture |
| ISBN | : 9783764362553 |
This drug is a landmark discovery, which consequently has become the definitive therapy for the treatment of erectile dysfunction (ED). Following the major breakthrough in the field of nitric oxide (NO)-physiology and pharmacology leading to sildenafil being marketed, the most current information is presented in this reference book, including ongoing research from several disparate groups about NO as endothelium-derived relaxing factor (EDRF) and also as a neurotransmitter for nerves innervating erectile tissue in mammals. The development of sildenafil as an oral phosphodiesterase-5 (PDE5) inhibitor drug for the treatment of ED resulted in one of the first products, which made its way successfully from basic NO research to routine clinical therapy. This volume addresses all fields of sildenafil application in both men and women. In a highly competitive research environment with a critical medical need for drug improvements the reader will learn more about clinical resistance to sildenafil treatment and the modalities to overcome the failure rates. The individual chapters cover clinical use, pharmacokinetics, pharmacodynamics, biochemistry, and cultural aspects. They are written by leading experts in their respective fields. Therefore, readers a?? whether professionals in the pharmaceutical industry, physicians treating ED, biochemists, chemists or pharmacologists a?? will find a detailed and up-to-date knowledge base about current research activities and an excellent overview for further research on this compound class and its cultural impact.
| Author | : Udo Dunzendorfer |
| Publisher | : Birkhäuser |
| Total Pages | : 203 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3034879458 |
Sildenafil, for the treatment of erectile dysfunction, is one of the first products that has made its way successfully from basic NO (nitrous oxide) research, to clinical routine therapy. Sidenafil, part of the Milestones in Drug Therapy series, presents the major breakthroughs in the field of NO physiology and pharmacology that led to the development of the drug, as well as clinical applications in one source guide. Written by leading experts in the field, each chapter covers aspects of clinical use and experience, pharmacokinetics, pharmacodynamics, biochemistry, and cultural science.
| Author | : Larry Katzenstein |
| Publisher | : |
| Total Pages | : 132 |
| Release | : 2001 |
| Genre | : Health & Fitness |
| ISBN | : 9780966371314 |
| Author | : Ruben Vardanyan |
| Publisher | : Academic Press |
| Total Pages | : 870 |
| Release | : 2016-01-07 |
| Genre | : Medical |
| ISBN | : 0124115241 |
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
| Author | : Doctor Herry Blend |
| Publisher | : Lulu.com |
| Total Pages | : 47 |
| Release | : 2019-06-24 |
| Genre | : Science |
| ISBN | : 0359748716 |
Viagra medicine has been a wonderful and effective treatment for erectile dysfunction in over 95%%%% impotent men who are suffering of persistent poor sexual arousal, poor sexual desire or libido, quick ejaculation, weak erection, small size penile muscular tissue and consequently not able to sexually perform perfectly with their lovable spouses in the bed. Viagra pills for men sex has been faked by several unqualified pharmacists and more more available in unaccredited online pharmacies than the original Viagra pills. In this book you will comprehensively learn how to identify fake Viagra Pills from original Viagra, several ways of knowing deceptive Book/Guide written for Viagra and Viagra Banners online, the general existing dangerous active ingredients with their deadly side effects in counterfeit Viagra Pills, Where and How to Securely Buy Original Viagra Pills Online Affordably...and more others. Do not use Viagra Pills for men with Cialis. This Viagra Book contains everything you need to know about Viagra.
| Author | : Charles D. Ciccone |
| Publisher | : F.A. Davis |
| Total Pages | : 1217 |
| Release | : 2013-03-21 |
| Genre | : Medical |
| ISBN | : 0803640048 |
A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!
| Author | : Randall Clint Baselt |
| Publisher | : |
| Total Pages | : 896 |
| Release | : 1989 |
| Genre | : Medical |
| ISBN | : |
Discussions include occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis and bibliographic references.
| Author | : Jaroslav F. Stark |
| Publisher | : John Wiley & Sons |
| Total Pages | : 754 |
| Release | : 2006-11-02 |
| Genre | : Medical |
| ISBN | : 047009317X |
Over 10 years after the publication of the second edition, Wiley now publishes the third edition of the popular volume Surgery for Congenital Heart Defects. Completely updated and expanded, this new edition describes step-by-step the surgical procedures for congenital heart defects and includes detailed illustrations for each operation. New in this edition are chapters on exercise testing, MRI, EP studies and catheter ablation of arrhythmias, extracorporeal circulatory support and paediatric lung transplantation. A greatly expanded ultrasound chapter contains numerous colour Doppler’s of many conditions. Surgery for Congenital Heart Defects, Third Edition: Provides complete coverage of the current issues in paediatric cardiac surgery Offers tips and surgical techniques to master difficult surgical situations Uniquely displays detailed illustrations for each operation, allowing surgeons to follow all operating procedures step-by-step Serves both as reference and training manual
| Author | : Thorsteinn Loftsson |
| Publisher | : Academic Press |
| Total Pages | : 179 |
| Release | : 2015-03-25 |
| Genre | : Medical |
| ISBN | : 0128014911 |
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. - Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products - Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes - Illustrates how to write and evaluate drug registration files
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 625 |
| Release | : 1994-09-05 |
| Genre | : Medical |
| ISBN | : 0080861180 |
Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the AmericanAssociation of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.
