Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 287
Release: 2001-07-02
Genre: Medical
ISBN: 0309132975

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Sexual Differentiation of the Brain

Sexual Differentiation of the Brain
Author: Akira Matsumoto
Publisher: CRC Press
Total Pages: 342
Release: 1999-12-21
Genre: Science
ISBN: 9781439832288

Sexual difference in the brain has long been one of the more intriguing research areas in the field of neuroscience. This thorough and comprehensive text uncovers and explains recent neurobiological and molecular biological studies in the field of neuroscience as they relate to the mechanisms underlying sexual differentiation of the brain. Attempts have been made to clarify sex differences in the human brain using noninvasive techniques such as magnetic resonance imaging. Sexual Differentiation of the Brain thoroughly examines these techniques and findings, providing an up-to-date, comprehensive overview written by leading researchers in the field. Just a few of the topics addressed include genetic contributions to the sexual differentiation of behavior; in-vitro studies of the effects of estrogen on estrogen receptor-transfected neuroblastoma cells; and the evolution of brain mechanisms controlling sexual behavior. Other topics include sexual differentiation of neural circuitry in the hypothalamus; structural sex differences in the mammalian brain; and sexual differentiation of cognitive functions in humans. With its revealing and informative chapters, as well as provocative treatment of the subject matter, Sexual Differentiation of the Brain helps shed new light on one of the most fascinating areas of brain research.

Disorders of Sex Development

Disorders of Sex Development
Author: John M. Hutson
Publisher: Springer Science & Business Media
Total Pages: 311
Release: 2012-01-14
Genre: Medical
ISBN: 3642229646

The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.

Textbook of Clinical Embryology

Textbook of Clinical Embryology
Author: Kevin Coward
Publisher: Cambridge University Press
Total Pages: 408
Release: 2013-10-31
Genre: Medical
ISBN: 110727625X

The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.

Sexual Differentiation of the Brain

Sexual Differentiation of the Brain
Author: Robert W. Goy
Publisher: MIT Press (MA)
Total Pages: 223
Release: 1979-12-01
Genre: Medical
ISBN: 9780262572071

Investigating the relative importance of genes, hormones, and environment in the formation of sexual behavior.

Genetic Sex Differentiation in Fish

Genetic Sex Differentiation in Fish
Author: T. J. Pandian
Publisher: CRC Press
Total Pages: 213
Release: 2012-06-05
Genre: Nature
ISBN: 1466517107

A comprehensive study of sex differentiation gonochoric and hermaphroditic fishes, this book examines sex chromosomes and sex determining genes, emphasizing the need to search for more than one sex-determining gene residing on different chromosomes. It traces the origin of hermaphrodites from secondary gonochores and explains the conservation of ho

Sex Differences in Physiology

Sex Differences in Physiology
Author: Gretchen Neigh
Publisher: Academic Press
Total Pages: 236
Release: 2016-05-10
Genre: Science
ISBN: 0128026081

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Sexual Differentiation of the Brain (2000)

Sexual Differentiation of the Brain (2000)
Author: Akira Matsumoto
Publisher: CRC Press
Total Pages: 673
Release: 2017-11-22
Genre: Science
ISBN: 1351357808

Sexual difference in the brain has long been one of the more intriguing research areas in the field of neuroscience. This thorough and comprehensive text uncovers and explains recent neurobiological and molecular biological studies in the field of neuroscience as they relate to the mechanisms underlying sexual differentiation of the brain. Attempts have been made to clarify sex differences in the human brain using noninvasive techniques such as magnetic resonance imaging. Sexual Differentiation of the Brain thoroughly examines these techniques and findings, providing an up-to-date, comprehensive overview written by leading researchers in the field. Just a few of the topics addressed include genetic contributions to the sexual differentiation of behavior; in-vitro studies of the effects of estrogen on estrogen receptor-transfected neuroblastoma cells; and the evolution of brain mechanisms controlling sexual behavior. Other topics include sexual differentiation of neural circuitry in the hypothalamus; structural sex differences in the mammalian brain; and sexual differentiation of cognitive functions in humans. With its revealing and informative chapters, as well as provocative treatment of the subject matter, Sexual Differentiation of the Brain helps shed new light on one of the most fascinating areas of brain research.

Maternal-Fetal and Neonatal Endocrinology

Maternal-Fetal and Neonatal Endocrinology
Author: Christopher S. Kovacs
Publisher: Academic Press
Total Pages: 1040
Release: 2019-10-12
Genre: Medical
ISBN: 0128148241

Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management systematically examines the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This reference volume expands coverage of specific disorders and diseases beyond the current endocrinology content on the market, which in most cases has a paragraph or no mention at all about pregnancy or aspects of fetal/neonatal development. - Formalized source of maternal/fetal endocrine physiology and pathophysiology - Key reference for fellows and residents for rarer endocrine pathologies - Integrated presentation of new molecular and genetic causes of endocrine disorders - Bridges the experience/knowledge gap of endocrinopathies rarely encountered in pregnancy