Separation Science
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| Author | : Satinder Ahuja |
| Publisher | : Elsevier |
| Total Pages | : 264 |
| Release | : 2003-01-11 |
| Genre | : Science |
| ISBN | : 0080501125 |
The basic objectives of this book are to: provide basic information on chromatography and separation science; show how simple extraction and partition processes provide the basis for development of chromatography and separation science; describe the role of chromatography and separation science in various fields; discuss the role of chromatography and separation science in development of new methodology; and present new evolving methods and how to select an optimum method. · The book covers the fundamental physical and chemical phenomena involved in separations · Provides a concise overview of the basics of transport phenomena and thermodynamics · Shows the importance of chromatography within separation science
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 332 |
| Release | : 2020-03-20 |
| Genre | : Science |
| ISBN | : 0128137460 |
Basic Multidimensional Gas Chromatography is aimed at the next generation of multidimensional gas chromatography users who will require basic training in the fundamentals of both GC and GCxGC. This book fills the current need for an inexpensive, straightforward guidebook to get new users started. It will help new users determine when to add or purchase a multidimensional system and teach them to optimize and maximize the capability of each system. Readers will also learn to select specific modes for each portion of a multidimensional analysis. This ideal resource is a concise, hard-hitting text that provides the facts needed to get users up and running. Provides a comprehensive and fundamental introduction to multidimensional gas chromatography Assists readers in determining when to add or purchase a multidimensional system Explains how a given system can be used to its maximum capacity and how users should choose specific modes for different portions of multidimensional analysis
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 115 |
| Release | : 2019-10-30 |
| Genre | : Science |
| ISBN | : 0309491703 |
Separation science plays a critical role in maintaining our standard of living and quality of life. Many industrial processes and general necessities such as chemicals, medicines, clean water, safe food, and energy sources rely on chemical separations. However, the process of chemical separations is often overlooked during product development and this has led to inefficiency, unnecessary waste, and lack of consensus among chemists and engineers. A reevaluation of system design, establishment of standards, and an increased focus on the advancement of separation science are imperative in supporting increased efficiency, continued U.S. manufacturing competitiveness, and public welfare. A Research Agenda for Transforming Separation Science explores developments in the industry since the 1987 National Academies report, Separation and Purification: Critical Needs and Opportunities. Many needs stated in the original report remain today, in addition to a variety of new challenges due to improved detection limits, advances in medicine, and a recent emphasis on sustainability and environmental stewardship. This report examines emerging chemical separation technologies, relevant developments in intersecting disciplines, and gaps in existing research, and provides recommendations for the application of improved separation science technologies and processes. This research serves as a foundation for transforming separation science, which could reduce global energy use, improve human and environmental health, and advance more efficient practices in various industries.
| Author | : J. Calvin Giddings |
| Publisher | : Wiley-Interscience |
| Total Pages | : 360 |
| Release | : 1991-01-16 |
| Genre | : Science |
| ISBN | : |
Unifies the complex welter of techniques used for chemical separations by clearly formulating the concepts that are common to them. The mass transport phenomena underlying all separation processes are developed in a simple physical-mathematical form. The limitations and optimum performance of alternative separation techniques and the factors enhancing and limiting separation power can thus be described and explored. Generously illustrated and contains numerous exercises. Long awaited in the scientific community, it breaks new ground in understanding separation processes.
| Author | : Satinder Ahuja |
| Publisher | : Academic Press |
| Total Pages | : 604 |
| Release | : 2010-11-11 |
| Genre | : Medical |
| ISBN | : 0123759811 |
Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS
| Author | : Haleem J. Issaq |
| Publisher | : CRC Press |
| Total Pages | : 782 |
| Release | : 2001-12-19 |
| Genre | : Science |
| ISBN | : 9780824705763 |
A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 881 |
| Release | : 2009-11-11 |
| Genre | : Science |
| ISBN | : 0123757274 |
Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. One-stop source for information on separation methods General overviews for quick orientation Ease of use for finding results fast Expert coverage of major separation methods Coverage of techniques for all sizes of samples, pico-level to kilo-level
| Author | : Satinder Ahuja |
| Publisher | : Elsevier |
| Total Pages | : 533 |
| Release | : 2011-09-21 |
| Genre | : Medical |
| ISBN | : 0080554199 |
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase
| Author | : George Z. Kyzas |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2019-08-27 |
| Genre | : Science |
| ISBN | : 9780128141786 |
Advanced Low-Cost Separation Techniques in Interface Science, Volume 30 helps scientists and researchers in academia and industry gain expert knowledge on how to use separation techniques at minimal cost and energy usage. It handles a broad range of highly relevant topics, including modern flotation techniques, low-cost materials in liquid-and gas-phase adsorption, new trends in molecular imprinting, graphenes in separation, nanobubbles and biopolymers in interface science, the reuse of biomaterials, green techniques for wastewaters, and modeling in environmental interfaces. The book shows that these techniques can be both attractive for both research and industrial purposes. It is intended for chemical engineers working in wastewater treatment industries, membrane industries, pharmaceutical industries, textile or tanneries industries, hybrid-topic industries and energy industries.
| Author | : Satinder Ahuja |
| Publisher | : Elsevier |
| Total Pages | : 740 |
| Release | : 2000-06-23 |
| Genre | : Technology & Engineering |
| ISBN | : 0080507794 |
It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments
