Sensory Nerves and Neuropeptides in Gastroenterology

Sensory Nerves and Neuropeptides in Gastroenterology
Author: Marcello Costa
Publisher: Springer Science & Business Media
Total Pages: 304
Release: 2013-11-21
Genre: Medical
ISBN: 1489907440

In the past 15 years much evidence has accumulated which indicates the paramount importance of sensory nerves in reg ulating functions of the gastrointestinal tract. In parallel, the attention of researchers in this field has been increas ingly attracted to the role played by neuropeptides in the normal and diseased gut. Basic research on the peculiar properties of capsaicin, the pungent ingredient from plants of the genus Capsicum, has allowed the gap between these two areas of research to be bridged. Sincethen, the study of gut afferents and neuropeptides has become more and more interconnected and recognized as a major avenue to understand ing the pathophysiology of various human diseases. It is widely recognized that a certain subset of primary afferents synthesize, store and release neuropeptides (such as tachykin nins and calcitonin gene-related peptide) from their central and peripheral endings, the latter being widely distributed in the alimentary canal and related organs (liver, pancreas). The First International Meeting on Sensory Nerves and Neuropeptides in Gastroenterology, held in Florence from December 4-5, 1989, sponsored and organized by Fondazione Internazionale Menarini, aimed to focus the current status of research in this field. The contributions presented at the meeting and in this book delineate a suggestive scenario in which sensory nerves of the gut, and the multiple messages they carry through the release of neuropeptides, are to be considered as a major target for the development of new drugs potentially useful in a number of diseases of the gastro intestinal tract.

Neuropeptide Function in the Gastrointestinal Tract

Neuropeptide Function in the Gastrointestinal Tract
Author: Edwin E. Daniel
Publisher: CRC Press
Total Pages: 521
Release: 2019-08-15
Genre: Science
ISBN: 1000693902

First published in 1991: This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides.

Neurogenic Inflammation in Health and Disease

Neurogenic Inflammation in Health and Disease
Author:
Publisher: Newnes
Total Pages: 371
Release: 2008-11-11
Genre: Medical
ISBN: 0080932622

Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain. Neurogenic inflammation in historical perspective Cardiac protection by nociceptive afferents Molecular mechanisms of nociception Sensory mechanisms in migraine pathophysiology Vagal signaling of visceral inflammation Neurogenic mechanisms in arthritis Therapeutic implications of vanilloid-type compounds

Neuropeptide Function in the Gastrointestinal Tract

Neuropeptide Function in the Gastrointestinal Tract
Author: Taylor & Francis Group
Publisher: CRC Press
Total Pages: 510
Release: 2021-09-30
Genre:
ISBN: 9780367250584

First published in 1991: This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides.

Neuropeptide Function in the Gastrointestinal Tract

Neuropeptide Function in the Gastrointestinal Tract
Author: Edwin E. Daniel
Publisher: CRC Press
Total Pages: 563
Release: 2019-08-15
Genre: Science
ISBN: 1000696987

First published in 1991: This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides.

Principles of Bone Biology

Principles of Bone Biology
Author: John P. Bilezikian
Publisher: Academic Press
Total Pages: 2074
Release: 2008-09-29
Genre: Medical
ISBN: 0080568750

Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Geriatric Gastroenterology

Geriatric Gastroenterology
Author: C. S. Pitchumoni
Publisher: Springer Science & Business Media
Total Pages: 660
Release: 2012-07-26
Genre: Medical
ISBN: 1441916237

As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Translational Pain Research

Translational Pain Research
Author: Lawrence Kruger
Publisher: CRC Press
Total Pages: 458
Release: 2009-11-24
Genre: Health & Fitness
ISBN: 1439812101

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical