How the Immune System Recognizes Self and Nonself

How the Immune System Recognizes Self and Nonself
Author: Daisuke Kitamura
Publisher: Springer Science & Business Media
Total Pages: 264
Release: 2008-04-08
Genre: Medical
ISBN: 4431738843

How do you discriminate yourself from other people? This question must sound odd to you since you easily recognize others at a glance and, without any effort, would not mistake them for yourself. However, it is not always easy for some people to discriminate themselves from others. For example, patients with schi- phrenia often talk with “others” living inside themselves. Thus it is likely that n- mally your brain actively recognizes and remembers the information belonging to yourself and discriminates it from the information provided by others, although you are not conscious of it. This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self: for example, bacteria, viruses, toxins, pollens, chemicals, transplanted organs, and even tumor cells derived from self-tissue. To this end the immune system recruits different kinds of immune cells, such as B and T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages.

Janeway's Immunobiology

Janeway's Immunobiology
Author: Kenneth Murphy
Publisher: Garland Science
Total Pages:
Release: 2010-06-22
Genre: Medical
ISBN: 9780815344575

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

The Limits of the Self

The Limits of the Self
Author: Thomas Pradeu
Publisher: OUP USA
Total Pages: 313
Release: 2012-02-27
Genre: Medical
ISBN: 0199775281

Immunology asserts that an individual can be defined through self and nonself. Thomas Pradeu argues that this theory is inadequate, because immune responses to self constituents and immune tolerance of foreign entities are the rule, not the exception.

Self and Non-Self in Early Buddhism

Self and Non-Self in Early Buddhism
Author: Joaquín Pérez-Remón
Publisher: Walter de Gruyter
Total Pages: 424
Release: 2012-10-25
Genre: Religion
ISBN: 3110804166

Sinceits founding by Jacques Waardenburg in 1971, Religion and Reason has been a leading forum for contributions on theories, theoretical issues and agendas related to the phenomenon and the study of religion. Topics include (among others) category formation, comparison, ethnophilosophy, hermeneutics, methodology, myth, phenomenology, philosophy of science, scientific atheism, structuralism, and theories of religion. From time to time the series publishes volumes that map the state of the art and the history of the discipline.

The Immune Self

The Immune Self
Author: Alfred I. Tauber
Publisher: Cambridge University Press
Total Pages: 370
Release: 1994
Genre: Medical
ISBN: 9780521574433

The Immune Self is the first extended philosophical critique of immunology.

Self, No Self?

Self, No Self?
Author: Mark Siderits
Publisher: OUP Oxford
Total Pages: 350
Release: 2013-01-31
Genre: Philosophy
ISBN: 0191668303

The nature and reality of self is a subject of increasing prominence among Western philosophers of mind and cognitive scientists. It has also been central to Indian and Tibetan philosophical traditions for over two thousand years. It is time to bring the rich resources of these traditions into the contemporary debate about the nature of self. This volume is the first of its kind. Leading philosophical scholars of the Indian and Tibetan traditions join with leading Western philosophers of mind and phenomenologists to explore issues about consciousness and selfhood from these multiple perspectives. Self, No Self? is not a collection of historical or comparative essays. It takes problem-solving and conceptual and phenomenological analysis as central to philosophy. The essays mobilize the argumentative resources of diverse philosophical traditions to address issues about the self in the context of contemporary philosophy and cognitive science. Self, No Self? will be essential reading for philosophers and cognitive scientists interested in the nature of the self and consciousness, and will offer a valuable way into the subject for students.

Being No One

Being No One
Author: Thomas Metzinger
Publisher: MIT Press
Total Pages: 896
Release: 2004-08-20
Genre: Medical
ISBN: 0262263807

According to Thomas Metzinger, no such things as selves exist in the world: nobody ever had or was a self. All that exists are phenomenal selves, as they appear in conscious experience. The phenomenal self, however, is not a thing but an ongoing process; it is the content of a "transparent self-model." In Being No One, Metzinger, a German philosopher, draws strongly on neuroscientific research to present a representationalist and functional analysis of what a consciously experienced first-person perspective actually is. Building a bridge between the humanities and the empirical sciences of the mind, he develops new conceptual toolkits and metaphors; uses case studies of unusual states of mind such as agnosia, neglect, blindsight, and hallucinations; and offers new sets of multilevel constraints for the concept of consciousness. Metzinger's central question is: How exactly does strong, consciously experienced subjectivity emerge out of objective events in the natural world? His epistemic goal is to determine whether conscious experience, in particular the experience of being someone that results from the emergence of a phenomenal self, can be analyzed on subpersonal levels of description. He also asks if and how our Cartesian intuitions that subjective experiences as such can never be reductively explained are themselves ultimately rooted in the deeper representational structure of our conscious minds.

Self and No-Self

Self and No-Self
Author: Dale Mathers
Publisher: Routledge
Total Pages: 256
Release: 2013-12-16
Genre: Psychology
ISBN: 1317723864

This collection explores the growing interface between Eastern and Western concepts of what it is to be human from analytical psychology, psychoanalytic and Buddhist perspectives. The relationship between these different approaches has been discussed for decades, with each discipline inviting its followers to explore the depths of the psyche and confront the sometimes difficult psychological experiences that can emerge during any in-depth exploration of mental processes. Self and No-Self considers topics discussed at the Self and No-Self conference in Kyoto, Japan in 2006. International experts from practical and theoretical backgrounds compare and contrast Buddhist and psychological traditions, providing a fresh insight on the relationship between the two. Areas covered include: the concept of self Buddhist theory and practice psychotherapeutic theory and practice mysticism and spirituality myth and fairy tale. This book explains how a Buddhist approach can be integrated into the clinical setting and will interest seasoned practitioners and theoreticians from analytical psychology, psychoanalytic and Buddhist backgrounds, as well as novices in these fields.

Attention, Not Self

Attention, Not Self
Author: Jonardon Ganeri
Publisher: Oxford University Press
Total Pages: 403
Release: 2017
Genre: Philosophy
ISBN: 0198757409

Jonardon Ganeri presents an account of mind in which attention, not self, explains the experiential and normative situatedness of human beings in the world. Attention consists in an organisation of awareness and action at the centre of which there is neither a practical will nor a phenomenological witness. Attention performs two roles in experience, a selective role of placing and a focal role of access. Attention improves our epistemic standing, because it is in the nature of attention to settle on what is real and to shun what is not real. When attention is informed by expertise, it is sufficient for knowledge. That gives attention a reach beyond the perceptual: for attention is a determinable whose determinates include the episodic memory from which our narrative identities are made, the empathy for others that situates us in a social world, and the introspection that makes us self-aware. Empathy is other-directed attention, placed on you and focused on your states of mind; it is akin to listening. Empathetic attention is central to a range of experiences that constitutively require a contrast between oneself and others, all of which involve an awareness of oneself as the object of another's attention. An analysis of attention as mental action gainsays authorial conceptions of self, because it is the nature of intending itself, effortful attention in action, to settle on what to do and to shun what not to do. In ethics, a conception of persons as beings with a characteristic capacity for attention offers hope for resolution in the conflict between individualism and impersonalism. Attention, Not Self is a contribution to a growing body of work that studies the nature of mind from a place at the crossroads of three disciplines: philosophy in the analytical and phenomenological traditions, contemporary cognitive science and empirical work in cognitive psychology, and Buddhist theoretical literature.