Science Of Synthesis Flow Chemistry In Organic Synthesis
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| Author | : T.F. Jamison |
| Publisher | : Thieme |
| Total Pages | : 932 |
| Release | : 2018-12-12 |
| Genre | : Science |
| ISBN | : 3132423343 |
The aim of this work is to convey the practice, power, and potential of flow chemistry to a larger audience. An emerging and strengthening trend is that flow chemistry is much more than the adaption of batch processes to flow systems. Rather, flow chemistry offers a new paradigm in the way we think about chemical synthesis. This volume demonstrates the enabling power of continuous flow to access new reaction types and different chemistry space and, to this end, it has been compiled by a team of pioneers and leaders, who present both the practical and conceptual aspects of this rapidly growing field. Included are the principles of reactor design, automation, and separations/purifications in flow systems, applications in photochemistry, electrochemistry, gaseous systems, immobilized reagents and catalysts, and multistep processes. The synthesis of peptides, carbohydrates, and pharmaceuticals is covered and several chapters give insight into the use of flow in an industrial context.
| Author | : A. B. Beeler |
| Publisher | : |
| Total Pages | : |
| Release | : 2018 |
| Genre | : |
| ISBN | : 9783132423350 |
| Author | : W A Smit |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 500 |
| Release | : 2007-10-31 |
| Genre | : Science |
| ISBN | : 1847551572 |
The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.
| Author | : Ferenc Darvas |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 307 |
| Release | : 2014-08-25 |
| Genre | : Technology & Engineering |
| ISBN | : 3110388758 |
"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.
| Author | : Charlotte Wiles |
| Publisher | : CRC Press |
| Total Pages | : 453 |
| Release | : 2016-04-19 |
| Genre | : Science |
| ISBN | : 143982472X |
While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists c
| Author | : Ferenc Darvas |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 568 |
| Release | : 2021-10-25 |
| Genre | : Technology & Engineering |
| ISBN | : 3110693771 |
The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.
| Author | : F. Serratosa |
| Publisher | : Elsevier |
| Total Pages | : 418 |
| Release | : 2013-10-22 |
| Genre | : Science |
| ISBN | : 1483290921 |
Contrary to all other books in the field of organic synthesis, this volume combines Corey's methodology, which is based on the concept of synthon and retrosynthetic analysis, with Evans' methodology based on the `Lapworth model' of alternating polarities. Using this approach, the formation of carbon-carbon bonds and the manipulation of functional groups are treated together, whereas the stereochemical aspects are considered separately. Emphasis is laid on the importance of rigid structures, whether in the starting materials, the synthetic intermediates or the transition states, as a means of controlling the stereochemistry of the organic compounds. Enclosed with the book is a copy of a miniprogram (CHAOS) for an IBM PC, or fully compatible computers, which is an interactive program, affording the beginner a fast and easy way of learning, exploring and looking for new synthetic schemes of molecules of moderate complexity. As a textbook on organic synthesis, this volume will be of immense value at university level.
| Author | : Upendra K. Sharma |
| Publisher | : Springer |
| Total Pages | : 400 |
| Release | : 2018-06-20 |
| Genre | : Science |
| ISBN | : 3319943286 |
This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions etc and is gradually gaining a lot of attention among organic chemist worldwide. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, this is a well warranted volume and complements the previous volume of Topics in Organometallic Chemistry ‘Organometallic Flow Chemistry’. This volume offers a versatile overview of the topic, besides discussing the recent progress in the flourishing area of flow chemistry in relevance to heterocyclic chemistry; it will also help researchers to better understand the chemistry behind these reactions. This in turn provides a platform for future innovations towards the designing of novel transformations under continuous flow. Thus, this volume will appeal to both the novices in this field as well as to experts in academia and industry.
| Author | : Toma Glasnov |
| Publisher | : Springer |
| Total Pages | : 119 |
| Release | : 2016-06-01 |
| Genre | : Science |
| ISBN | : 331932196X |
This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.
| Author | : Ferenc Darvas |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 448 |
| Release | : 2021-10-25 |
| Genre | : Technology & Engineering |
| ISBN | : 3110693763 |
The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. A strong insight in driving a chemical reaction is crucial for a deeper understanding of new potential technologies. New procedures for warranty of safety and green principles are discussed. Vol. 1: Fundamentals.
